ABSTRACT
The antibacterial activity of different extracts of Quercus ilex bark (Fagaceae) was studied in vitro against seven reference strains of bacteria by using a disc-diffusion method and agar-dilution method. The ethyl acetate extract (QE), n-butanol extract (QB) and final aqueous layer (QA) were effective against all bacterial strains tested at MICs ranging from 128 to 512 microg/ml. The n-hexane extract (QH) and dichloromethane extract (QD) showed no activity.
Subject(s)
Anti-Bacterial Agents/pharmacology , Plant Bark/chemistry , Plant Extracts/pharmacology , Quercus/chemistry , Anti-Bacterial Agents/chemistry , Anti-Bacterial Agents/isolation & purification , Bacillus subtilis/drug effects , Bacillus subtilis/growth & development , Disk Diffusion Antimicrobial Tests/methods , Escherichia coli/drug effects , Escherichia coli/growth & development , Klebsiella pneumoniae/drug effects , Klebsiella pneumoniae/growth & development , Morocco , Plant Extracts/chemistry , Plant Extracts/isolation & purification , Proteus mirabilis/drug effects , Proteus mirabilis/growth & development , Pseudomonas aeruginosa/drug effects , Pseudomonas aeruginosa/growth & development , Salmonella typhimurium/drug effects , Salmonella typhimurium/growth & development , Staphylococcus aureus/drug effects , Staphylococcus aureus/growth & development , Staphylococcus epidermidis/drug effects , Staphylococcus epidermidis/growth & development , Streptococcus agalactiae/drug effects , Streptococcus agalactiae/growth & development , Streptococcus pneumoniae/drug effects , Streptococcus pneumoniae/growth & development , Vibrio cholerae/drug effects , Vibrio cholerae/growth & developmentABSTRACT
The stereochemistries of the title compounds, both C(16)H(24)Cl(2)O, have been established by X-ray diffraction. In both structures, the seven-membered ring adopts the same conformation, whereas the six-membered ring shows an envelope conformation in the epoxydodecane structure and a boat conformation in the dodecan-9-one structure.
