Late-onset occult cerebrospinal fluid leakage after orbital exenteration.

Orbital exenteration can be complicated by cerebrospinal fluid leakage, mostly during surgery. Late-onset cerebrospinal fluid leakage that occurs years after the initial orbital exenteration is rare. The authors report a case of cerebrospinal fluid leakage that occurred 4 years after orbital exenteration that was not due to tumor recurrence. The leakage was managed successfully by the application of cyanoacrylate tissue glue. No complication was encountered.