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1.
An Med Interna ; 16(5): 247-8, 1999 May.
Article in Spanish | MEDLINE | ID: mdl-10389311

ABSTRACT

The objective of this clinical case is to suggest that Cytomegalovirus (CMV) should be taken into consideration when dealing with infections produced by opportunistic microorganisms in immunocompromised patients who have fever of unknown origin and especially when accompanied by symptoms and signs of interstitial pneumonia. In the case we report of CMV active infection in a patient with acute myeloid leukemia, the anti-CMV specific treatment (ganciclovir) was iniciated following a positive polymerase chain reaction (PCR) result for CMV. The patient initially experienced an improvement but later worsened and expired. At present there are sensitive and specific techniques such as PCR which make it possible to start specific treatment as soon as the diagnosis of CMV active infection is made.


Subject(s)
Cytomegalovirus Infections/diagnosis , Leukemia, Myeloid/complications , Opportunistic Infections/diagnosis , Pneumonia, Viral/diagnosis , Cytomegalovirus Infections/complications , Cytomegalovirus Infections/drug therapy , Fatal Outcome , Female , Humans , Leukemia, Myeloid/immunology , Middle Aged , Opportunistic Infections/complications , Opportunistic Infections/drug therapy , Pneumonia, Viral/complications , Pneumonia, Viral/drug therapy
2.
An. med. interna (Madr., 1983) ; 16(5): 247-248, mayo 1999.
Article in Es | IBECS | ID: ibc-49

ABSTRACT

El objetivo del presente trabajo ha sido poner de manifiesto que ante un enfermo inmunodeprimido que presenta fiebre de origen desconocido y un cuadro de neumonía intersticial hay que descartar una infección producida por microorganismos oportunistas y sobre todo por Citomeglovirus (CMV). Presentamos un caso de infección activa por CMV en una paciente con leucemia aguda mieloide a la que se administró un tratamiento anti-CMV específico (ganciclovir) al obtenerse un resultado positivo para CMV por la técnica de reacción en cadena de la polimerasa (PCR). La paciente mejoró inicialmente pero más tarde empeoró y falleció. Actualmente disponemos de técnicas sensibles y específicas como la PCR que hace posible empezar el tratamiento tan pronto como se hace el diagnóstico de la infección activa por CMV (AU)


Subject(s)
Female , Middle Aged , Humans , Fatal Outcome , Leukemia, Myeloid , Opportunistic Infections/complications , Pneumonia, Viral/complications , Cytomegalovirus Infections/complications , Leukemia, Myeloid/complications , Leukemia, Myeloid/immunology , Opportunistic Infections/diagnosis , Opportunistic Infections/drug therapy , Pneumonia, Viral/diagnosis , Pneumonia, Viral/drug therapy , Cytomegalovirus Infections/diagnosis , Cytomegalovirus Infections/drug therapy
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