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Anesteziol Reanimatol ; 61(4): 296-300, 2016 Jul.
Article in Russian | MEDLINE | ID: mdl-29470901

ABSTRACT

At patients with the verfied diagnosis have a cholelithiasis, transferred a laparoscopic holetsistektomy against the combined general anesthesia with muscle relaxants and artificial lung ventilation with use ofvarious anesthetics, the intraerythrocyte intensifi- cation of processes of peroxidation of lipids is established, and in a membrane of erythrocytes essential change of the contents and a ratio of the proteins and lipids responsible for structure, stabilization of a membrane and function of erythrocytes is revealed. Application of a sevoflurane, in comparison with propofol and, especially, a halothane, to a lesser extent influences structurally functional properties of erythrocytes that demands profile development ofpharmacological correction of the revealed violations.


Subject(s)
Anesthesia, General/methods , Anesthetics, Inhalation/adverse effects , Anesthetics, Intravenous/adverse effects , Cholecystectomy, Laparoscopic/methods , Cholelithiasis/surgery , Erythrocytes/drug effects , Erythrocytes/metabolism , Female , Humans , Lipid Peroxidation/drug effects , Membrane Lipids/metabolism , Membrane Proteins/metabolism , Middle Aged , Respiration, Artificial
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