[Combined extract of Sabal palm and nettle in the treatment of patients with lower urinary tract symptoms in double blind, placebo-controlled trial].

A multicenter, prospective clinical trial was performed to study efficacy and tolerance of a compound drug PRO 160/120 in the elderly men with lower urinary tract symptoms (LUTS) due to benign prostatic hyperplasia (BPH). A total of 257 patients were randomized into two groups. Group 1 of 129 patients received PRO 160/120; group 2 of 128 patients received placebo. In 2-week induction blind phase of placebo the patients received for 24 weeks 1 capsule of the drug or placebo twice a day in conditions of double blind study. The double blind phase was followed by an open control period for 24 weeks when all the patients received PRO 160/120. Treatment efficacy evaluation was based on I-PSS, quality of life index, urodynamic and ultrasonography evidence. PRO 160/120 was superior to placebo by attenuating LUTS assessed by I-PSS, improved obstructive and irritative symptoms, was effective in patients with moderate and severe symptoms. Tolerance of the plant extract was good.

[Distant pulse-wave lithotripsy in the Central Clinical Air Force Hospital ]. / Prioritetnaia distantsionnaia udarno-volnovaia litotripsiia v tsentral'nom voennom klinicheskom aviatsionnom gospitale.

With participation of the specialists from the 7th Central Military Clinical Aviation Hospital 4 pulse-wave complexes "Urat-P", "Urat-P2", "Ulitho", "Cholelithotriptor" were developed and introduced into clinical practice of the hospital. Distant pulse-wave lithotripsy was conducted 3035 patients (358 persons from flying staff). It is the main method of urolithiasis treatment, especially in the flying staff. Its efficiency is more than 96%. The modern models of lithotriptors are effective in destruction of biliary and urinary calculi and the applied parameters of wave impulses don't impact on the organs and tissues. The sphere of use of pulse-wave effect in the clinical practice was extended.

[Diagnosis and treatment of nephroptosis in flying personnel]. / Diagnostika i lechenie nefroptoza u letnogo sostava.

Fifty human subjects of flying personnel and 25 human subjects of ground personnel suffered from nephroptosis mean age of which was 28.7 +/- 0.9 years have been under study. Dynamics observation of flying personnel for a period of 1-8 years revealed that the persons suffered from nephroptosis of the 1st stage are capable of performing the flying activity without limitations and need such observation and performance of the appropriate treatment- and--prophylactic measures. With the nephroptosis of stage II (27 pilots), the early operative treatment for eliminating the nephroptosis is indicated. The post-operative supervision of such patients is mastered. The nephropexy has been performed in 24 pilots; more recently, 23 persons were allowed to perform flying activities without restrictions, there were no nephroptosis recurrences. In the patients group of ground servicing personnel (26 persons) there have effectively been performed 20 nephropexies. Thus, it has been possible to overcome the nephroptosis and to improve the functional state of the kidneys. The operative treatment results allow one to recommend the early operative treatment of the stage II nephroptosis in the flying personnel even in the absence of the complicated nephroptosis and pronounced disorder of the kidney function.

[The work experience of the Central Military Aviation Research Hospital in the occupational rehabilitation of flight personnel after lithotripsy]. / Opyt raboty TsVNIAG po professional'noi reabilitatsii letnogo sostava posle litotripsii.

The evolution of the domestic-certified lithotriptors has made a complete professional rehabilitation of all pilots (100%) suffered from urolithiasis without operative intervention possible. Of 156 pilots who have been exposed to remote shock-wave lithotripsy (RSWL) in recent three years 120 individuals (93%) had the urate stones in the renal calyces. Before introducing the RSWL in clinical practice such concrement were recognized as inoperable and the urolithic pilots have no prospects for continuation of their flying activities. After the RSWL application there was a decrease in the secretory-excretory renal function due to the disturbed urodynamics by the migratory fragments of crushed stones in the renal system. The recovery of renal function occurred after complete passage of the crushed stone fragments. Depending on the composition of a crushed concrement, severity of inflammatory process taking place in the kidneys and urinary tracts, the special program of countermeasures to prevent relapsed lithogenesis was recommended for use by the patients. The relapse of renal stone formation after RSWL application was noted in 4 (3.2%) pilots. In these pilots, the concrements were recrushed by the mentioned method and professional qualification of above individuals was retained. Until recently, the treatment of cholelithic disease was recognized as a purely surgical problem--with the introduction of RSWL of renal stone into clinical practice there appeared real possibility to apply the similar approach to crushing the gallstones. To attain these ends, the experimental studies with the use of lithotriptor "URAT-P" have been performed. 140 gallstones of 0.5 to 2.0 cm in size were crushed. The parameters of shock waves are determined.(ABSTRACT TRUNCATED AT 250 WORDS)

[The characteristics or urolithiasis in flight personnel and the treatment results using a method of extracorporeal shockwave lithotripsy on the Russian lithotripter Urat-P2]. / Nekotorye osobennosti mochekamennoi bolezni u letnogo sostava i rezul'taty lecheniia ee metodom distantsionnoi udarno-volnovoi litotripsii na otechestvennom litotriptere "Urat-P2".

Urolithiasis occurs more frequently in the pilots than in the ground-service personnel. To decrease a damaging effect of the focused shock waves on the renal tissue while using remote lithotripsy technique, a new domestic-certified lithotriptor "URAT-P2" which shows a significantly low energy of shock wave with sufficient effectiveness of crushing the renal stones, is devised. Urolithiasis in the pilots is apparent at the early stages of its development and its complicated forms are less common than in the subjects of other professions. The stones are predominantly located in the renal calyces (73,3% of cases), in the left kidney and urethra in 63,3% of cases and there were urate stones in 40% of cases. The clinical use of the URAT-P2 complex in 30 pilots indicated that it holds advantages over the production domestic-certified lithotriptor. The stones are crushed in all the patients but the complications associated with a negative effect of the focused shock waves on the renal tissue are absent. The use of the new lithotriptor for treating urolithiasis in the pilots will allow one to improve the treatment response and to maintain professional worthiness of the pilots for a long time.

[Ultrasonographic control of the renal state after remote shock- wave nephroureterolithotripsy]. / Ul'trazvukovoi kontrol' za sostoianiem pochki posle distantsionnoi udarnovolnovoi nefroureterolitotripsii.

The paper is concerned with the problems of ultrasound diagnosis of nephrolithiasis during distant shock-wave nephroureterolithotripsy. A scheme of ultrasound investigation of patients was developed. The morpho-functional state of the kidney was assessed during lithotripsy of calculi of different localization. A skialogical picture of the most spread concrements was described. USI was shown to be a highly effective diagnostic method permitting one to determine a degree of renal regeneration during therapy.