[The effect of stimulators of immunoglobulin biosynthesis on the phenomenon of lymphocyte transformation by macrophages]. / Vliianie stimuliatorov biosinteza immunoglobulinov na fenomen makrofagal'noi transformatsii limfotsitov

The effect of pyrogenal and of the adjuvant of Freund's type on transformation of blood lymphocytes into macrophagal cells was studied. Experiments were conducted on rabbits with the use of the method of lymphocyte culture in vitro. These stimulants of immunogenesis increased the intensity of the process of lymphocyte transformation in a culture. It was also noted that action of pyrogenal and of complete adjuvant of Freund's type was expressed as soon as the first day after the administration. As supposed, there existed an interrelationship between the capacity of lymphocytes to transform into cells of macrophagal type and formation of immunological response of the organism.