Large vessel stroke in six patients following SARS-CoV-2 infection: a retrospective case study series of acute thrombotic complications on stable underlying atherosclerotic disease.

BACKGROUND AND PURPOSE: Ischaemic stroke has been described in association with COVID-19. Several pathophysiological mechanisms have been suggested, i.e. prothrombotic state, cardiac injury etc. It was sought to assess the potential association between ischaemic stroke associated with SARS-CoV-2 infection and underlying atherosclerotic lesions. METHODS: A retrospective analysis of stroke related to large vessel occlusion was conducted amongst patients with SARS-CoV-2 infection and underlying mild atherosclerotic disease, between 19 March and 19 April 2020 in six different stroke centers in the Île-de France area, France. RESULTS: The median age was 52 years, median body mass index was 29.5 kg/m2 . All patients displayed previous vascular risk factors such as high blood pressure, diabetes, dyslipidemia or body mass index > 25. The delay between the first respiratory symptoms of COVID-19 and stroke was 11.5 days. At baseline, all had tandem occlusions, i.e. intracerebral and extracerebral thrombus assessed with computed tomography or magnetic resonance imaging. Cases displayed a large thrombus in the cervical carotid artery with underlying mild non-stenosing atheroma, after an etiological workup based on angio-computed tomography or magnetic resonance imaging and/or cervical echography. CONCLUSION: Our study should alert clinicians to scrutinize any new onset of ischaemic stroke during COVID-19 infection, mainly in patients with vascular risk factors or underlying atherosclerotic lesions.

Surveying colloid sedimentation by coplanar waveguides.

By using coplanar waveguides, direct access to the dielectric properties of aqueous solutions of polystyrene beads with different diameters from 330 nm to 10 µm is provided. The relative variation of the transmission parameter with respect to water is monitored, ranging from [Formula: see text] obtained for a 9.5% solution with 330 nm diameter beads to ∼22% for 10 µm diameter particles at the same concentration. To highlight its applicability in biosensing, the technique was further employed to survey the clustering between biotin and streptavidin-coated beads. The transmission parameter displays a ∼50% increase for mixtures containing nine volumes of biotin and one volume of streptavidin-modified beads (4.5 ng µl(-1) of streptavidin) and reaches ∼400% higher values when equal volumes of biotin and streptavidin-coated beads (22.5 ng µl(-1) of streptavidin) were mixed.

[Subfascial endoscopic perforating veins section]. / Ligatura endoscopica subfasciala a venelor perforante insuficiente.

AIM: Subfascial endoscopic perforating veins section (SEPS) is a modern surgical method used in the treatment of chronic venous insufficiency. The paper presents the postoperative results using SEPS technique at the patients with chronic venous insufficiency of the inferior limbs of different etiologies. MATERIAL AND METHOD: We followed 26 patients, 16 women and 10 men, with ages between 16-75 years, with chronic venous insufficiency at the inferior legs. 20 patients had only one inferior limb affected by the disease and 6 patients had both limbs involved. They were, after CEAP clinical criterion, in C4, C5 and C6 classes and they had three different etiologies as primary varices with an evolutive period of 20 years, postthrombotic syndrome and congenital varices. We performed 32 SEPS operations in the 1-rst Clinic of Surgery, University of Medicine and Pharmacy "Victor Babes" Timisoara. RESULTS: The time of healing and postoperative complications were reduced after SEPS procedures. The healing is 100% at three months after surgery. The check up after 12 months showed a rate of 87.5% of healing. We recorded 4 unilateral relapses at patients that had postthrombotic syndrome. DISCUSSIONS: The study realized in our clinic comparing with other studies from the literature, shows that our results are similar to that recorded in medical centers from other countries demonstrating the superiority of SEPS methods comparing with the classical Linton or Felder methods of perforating veins ligation.

Epidemiological investigations on viral hepatitis in preschool and school communities. Note III. Sources of infection for HBsAg carriers and former viral hepatitis patients.

HBsAg carriers and viral hepatitis B patients detected in preschool and school communities as well as members of their families were subjected to thorough epidemiological investigations. The source of infection was represented by the community in 33.3% of the preschool children and in 26.5% of the schoolchildren and by the family in 10% of the former and 29.4% of the latter.