ABSTRACT
Examination and intervention are always the causes of agitation, anxiety, and fear in children's lives. This study aimed to investigate the effectiveness of promethazine hydrochloride in reducing children's agitation during the ocular examination for trauma. In this interventional-clinical trial study, a total of 62 children referred to Al-Zahra Ophthalmology Hospital in Zahedan, Iran, were evaluated in two matched groups (case (n = 31) and control (n = 31)) for an initial examination of ocular trauma. Finally, the intervention was performed (giving placebo or promethazine hydrochloride cough syrup 20 minutes before the initial ocular examination at 0.5 mg/kg), and the demographic information form and researcher-made questionnaire modeled on the Cohen-Mansfield Agitation Inventory (CMAI) were completed. The obtained results revealed that the mean scores of physical/aggressive behaviors (p Ë 0.001), physical/nonaggressive behaviors (p = 0.013), verbal/aggressive behaviors (p Ë 0.001), and hiding behaviors (p Ë 0.001) were significantly lower in the promethazine hydrochloride-receiving group than the placebo group. These findings demonstrated that promethazine hydrochloride cough syrup facilitated the examination among the pediatric patients who suffered from traumatic ocular injuries. However, further studies in this field need to be carried out through randomized controlled trials.
ABSTRACT
Rheumatoid arthritis (RA) is a multifactorial disease affecting the immune system and many tissues in the body. This study aimed to evaluate the effect of magnesium supplementation on insulin resistance and fasting blood sugar (FBS) of patients with RA. In this prospective uncontrolled before-after study, RA patients referring to Rheumatology clinics of Qom City from January 2020 to January 2021 were evaluated. First, the patients received the routine rheumatoid arthritis treatment including 5 mg Prednisolone and 200mg Hydroxychloroquine daily for 6 months and FBS and insulin levels were measured after. Then, they received the routine arthritis rheumatoid treatment in addition to 300 mg/day oral Magnesium sulfate for 6 months and then, FBS and insulin levels were measured. The Homeostasis Model Assessment of insulin resistance (HOMA-IR) was used for determining insulin resistance. Thirty five patients with RA and the mean age of 49.83±2.58 years were enrolled. Twenty eight cases (80%) were female and 7 cases (20%) were male. The mean HOMA-IR before and after consumption of oral magnesium were 3.04±0.29 and 2.43±0.19, respectively. Statistically significant differences were found between FBS, insulin and HOMA-IR before and after consumption of oral magnesium (p<0.05). Our data suggested that magnesium supplementation reduces FBS, insulin and HOMA-IR in patients with rheumatoid arthritis. Thus, magnesium supplements may be an alternative method for prevention of type 2 diabetes in RA patients.
ABSTRACT
Acinetobacter baumannii is a rare but dangerous gram-negative bacteria causing nosocomial infections, especially in intensive care units. The increased use of antibiotics in the treatment of bacterial infections leads to drug resistance, delays, or failures in treatment. The patient is a 48-year-old man with coronavirus disease (COVID-19) being treated in the intensive care unit. After contracting Acinetobacter baumannii, the patient's condition deteriorated, and he developed severe pulmonary problems. Due to the unknown presence of Acinetobacter baumannii in the patient, this bacterium transmitted to six other patients in the ward, which resulted in their deaths. In this report, we describe the causes and risk factors of the disease, and the results of laboratory tests and therapeutic processes.
ABSTRACT
Background and objectives:As blind women have usually been known as a group at risk, they should be necessarily considered to a larger extent in health consulting programs. Therefore, the present survey was aimed to investigate blind women empowerment toward sexual and reproductive health care. MaterialsA quasi-experimental study was conducted on all 26 blind women covered by the Blind Society in the Azerbaijan province. A researcher-made questionnaire was run to collect data using an interview that included knowledge, attitude and behavior items. Intervention was done in two days, and all participants were followed-up for two weeks after intervention. Results:Subjects had a mean age of 36.84±9.8 years. Overall, 42.3% of them were blind women and 57.7% had low vision. Women knowledge score about menstrual health, healthy fertility, sexually transmitted diseases and pregnancy was 2.7±1.03, 1.2±0.9, 2.4±0.81 and 3.6±1.2, respectively before intervention, and it has increased significantly to 3.7± 0.51, 2.±0.7, 3.7±0.45 and 4.8±0.32, respectively after intervention (p<0.0001). In brief, results revealed that, on average, subjects' attitude was also remarkably better, as the score rose from 21.07±3.17 before intervention to 25.26±3.24 after interventions (p<0.0001). Conclusion:It seems that participants were poorly aware of reproductive health, but providing education on reproductive and sexual health was likely to be useful for this group; moreover, it should be prioritized in joint programs of medical universities and welfare institutions.