ABSTRACT
OBJECTIVE: To determine the common factors that affect the diagnostic quality of radiographs in radiodiagnostic centers in Lagos state, Nigeria. METHODS: Self-administered questionnaires containing both open- and close-ended questions were distributed to the supervising radiographers in radiodiagnostic centers within the Lagos metropolis. The questions asked included the film/reject ratio in each center and reasons why each film was rejected. RESULTS: Faulty x-ray machines, movement on the part of the patient, poor darkroom film processing, and suboptimal radiographic techniques were the main reasons respondents identified as factors commonly responsible for the production of faulty films. In some cases, more than one of these factors was responsible. CONCLUSION: There is a need to routinely ensure that x-ray machines are properly calibrated in order to reduce the rate of film rejects in our x-ray facilities. In addition, equipment that is old and cannot be properly calibrated should be replaced. This would guarantee optimum performance and reduce radiation dose to patients and personnel. Younger radiographers should also be open to mentoring by older colleagues so they can acquire useful tips on how to reduce the production of films with unacceptable diagnostic quality. They should be encouraged to attend continuing education programs for improved expertise. Also, quality control and maintenance programs such as the reject film analysis or regular equipment maintenance should be enforced in radiodiagnostic centers.
ABSTRACT
BACKGROUND: Hyperhomocysteinemia is a potentially modifiable risk factor for stroke, and may have a negative impact on the course of ischaemic stroke. The role of hyperhomocysteinemia as it relates to stroke in Africans is still uncertain. The objective of this study was to determine the prevalence and short-term impact of hyperhomocysteinemia in Nigerians with acute ischaemic stroke. We hypothesized that Hcy levels are significantly higher than in normal controls, worsen stroke severity, and increase short-term case fatality rates following acute ischaemic stroke. METHODS: The study employed both a case-control and prospective follow-up design to study hospitalized adults with first - ever acute ischaemic stroke presenting within 48 hours of onset. Clinical histories, neurological evaluation (including National Institutes of Health Stroke Scale (NIHSS) scores on admission) were documented. Total plasma Hcy was determined on fasting samples drawn from controls and stroke cases (within 24 hours of hospitalization). Outcome at 4 weeks was assessed in stroke patients using the Glasgow Outcome Scale (GOS). RESULTS: We evaluated 155 persons (69 acute ischaemic stroke and 86 healthy controls). The mean age +/- SD of the cases was 58.8 +/- 9.8 years, comparable to that of controls which was 58.3 +/- 9.9 years (T = 0.32; P = 0.75). The mean duration of stroke (SD) prior to hospitalization was 43.5 +/- 38.8 hours, and mean admission NIHSS score was 10.1 +/- 7.7. Total fasting Hcy in stroke patients was 10.2 +/- 4.6 umol/L and did not differ significantly from controls (10.1 +/- 3.6 umol/L; P = 0.88). Hyperhomocysteinemia, defined by plasma Hcy levels > 90th percentile of controls (>14.2 umol/L in women and >14.6 umol/L in men), was present in 7 (10.1%) stroke cases and 11 (12.8%) controls (odds ratio 0.86, 95% confidence interval 0.31 - 2.39; P > 0.05). In multiple regression analysis admission NIHSS score (but not plasma Hcy) was a significant determinant of 4 week outcome measured by GOS score (P < 0.0001). CONCLUSION: This exploratory study found that homocysteine levels are not significantly elevated in Nigerians with acute ischaemic stroke, and admission Hcy level is not a determinant of short-term (4 week) stroke outcome.
