ABSTRACT
PURPOSE: To report the histopathological results of lacrimal gland biopsies over a 21-year period in a tertiary referral centre in the United Kingdom. To the best of our knowledge, this represents the largest series to be published in the United Kingdom. METHODS: A retrospective observational review was carried out for patients who underwent lacrimal gland biopsies in a tertiary referral centre at the University Hospitals of Leicester, United Kingdom between the years of 2000 and 2021. RESULTS: Lacrimal gland biopsies were performed on 248 patients during the specified 21-year period. They comprised 157 (63.3%) females and 91 (36.7%) males. The mean age at presentation was 50.8 years (range 15-94 years). The majority of patients were Caucasian (69.4%, n = 172) followed by Asians (25.0%, n = 62), African/Afro-Caribbean (4.8%, n = 12) and other ethnicities (0.8%, n = 2). The most common histopathological diagnosis was chronic inflammation dacryoadenitis (69.0%, n = 171) followed by lymphomas (15.3%, n = 38). CONCLUSION: Our study shows that chronic inflammation accounts for the majority of histopathological diagnosis followed by lymphoproliferative disorders.
Subject(s)
Dacryocystitis , Lacrimal Apparatus Diseases , Lacrimal Apparatus , Adolescent , Adult , Aged , Aged, 80 and over , Female , Humans , Male , Middle Aged , Young Adult , Biopsy/methods , Dacryocystitis/pathology , Inflammation/pathology , Lacrimal Apparatus/pathology , Lacrimal Apparatus Diseases/diagnosis , Lacrimal Apparatus Diseases/pathology , Retrospective StudiesSubject(s)
Uveal Diseases/diagnosis , Aged , Choroid Diseases/diagnostic imaging , Choroid Diseases/physiopathology , Exudates and Transudates , Follow-Up Studies , Functional Laterality , Humans , Magnetic Resonance Imaging , Male , Ophthalmoscopy , Retinal Detachment/diagnosis , Retinal Detachment/physiopathology , Ultrasonography , Uveal Diseases/physiopathologySubject(s)
Anesthetics, Local/administration & dosage , Anti-Infective Agents/administration & dosage , Conjunctiva/microbiology , Endophthalmitis/prevention & control , Eye Infections, Bacterial/prevention & control , Lidocaine/administration & dosage , Administration, Topical , Anti-Infective Agents/pharmacokinetics , Bacteria/isolation & purification , Colony Count, Microbial , Endophthalmitis/microbiology , Eye Infections, Bacterial/microbiology , Fluoroquinolones/administration & dosage , Fluoroquinolones/pharmacokinetics , Gatifloxacin , Humans , Injections , Ophthalmic Solutions/administration & dosage , Ophthalmic Solutions/pharmacokinetics , Povidone-Iodine/administration & dosage , Povidone-Iodine/pharmacokinetics , Single-Blind Method , Vitreous BodyABSTRACT
Ectropion is a condition in which the lower eyelid turns outwards from the globe. It is commonly due to age related involutional laxity of the lid tissue. Ectropion may also be secondary to scarring or contracture of the periorbital skin and underlying tissues which pulls the eyelids outwards. Jessner's lymphocytic infiltrate is a rare and enigmatic dermatological condition which is uncommon in the elderly. We describe a case of recurrent ectropion following redo lid surgery in which Jessner's lymphocytic infiltrate was fortuitously diagnosed on skin biopsy. We are unaware of any report in the literature describing recurrent cicatrical ectropion due to this condition.
