ABSTRACT
Partial deficiency of distal radial and volar cartilage plate growth is the main pathology in Madelung's deformity. Surgical treatment can use a Taylor Spatial Frame (TSF) external fixator, which provides simultaneous multiplanar correction and lengthening after radial osteotomy, sparing Vickers' ligament and the ulna. We sought to evaluate the radiological and functional results of Madelung's deformity correction by TSF, by retrospectively analyzing eight Madelung's deformities in seven patients between August 2011 and May 2015. Mean age was 14.8 years (range, 11-26), and mean follow-up 35.1 months (24-78). We evaluated demographic data and pre- and post-operative radiological and functional results. Mean preoperative visual analog pain scale score improved from 7.7 to 1.6. Mean preoperative DASH score improved from 19.1 (9.5-46.6) to 3.7 (2.3-6.8). Mean preoperative radial length improved from 184 mm (138-209) to 196 mm (142-213). We think that software-based correction using a TSF is a safe solution in Madelung's deformity, with minimal margin of error and risk of postoperative stiffness and infection. LEVEL OF EVIDENCE: IV.
Subject(s)
Radius , Wrist Joint , Adolescent , External Fixators , Growth Disorders , Humans , Osteochondrodysplasias , Osteotomy/methods , Radius/abnormalities , Radius/surgery , Retrospective Studies , Wrist Joint/surgeryABSTRACT
Allergic rhinitis is still a commonly investigated disease all over the world. Allergens are usually in the nature of glycoprotein or protein which interact with antibodies resulting in the formation of specific Ig E in the body 1. It is presumed that some environmental factors play an important role in their clinics. In allergic rhinitis, symptoms usually occur after the interaction of nasal mucosa with allergens. Allergens may be indoors, outdoors or in both environments. House-dust contains most of the indoor allergens. Mites are the most egregious allergen in house dust. D. pteronyssinus is commonly seen in European countries, D. farinae is mostly seen in North America. House-dust mites play an important role in allergic sensitization of individuals in Turkey. Perennial allergic rhinitis is a common chronic disorder that results most frequently from sensitivity to house-dust mites. National and international guidelines for the management of allergic rhinitis recommend that house and dust mite avoidance measures be considered for all patients with house-dust mite provoked rhinitis. Symptoms of allergic rhinitis are related to the environmental mite level in which patients live. The aim of this study is to show the relationship between mite levels and symptoms of allergic rhinitis diagnosed patients and the change of mite levels in the environment after appropriate education.
Subject(s)
Antigens, Dermatophagoides , Environmental Exposure/prevention & control , Mites , Patient Education as Topic , Rhinitis, Allergic, Perennial/prevention & control , Animals , Follow-Up Studies , Humans , Preventive Health Services/methods , Rhinitis, Allergic, Perennial/epidemiology , TurkeyABSTRACT
Allergic rhinitis is still a commonly investigated disease all over the world. Allergens are usually in the nature of glycoprotein or protein which interact with antibodies resulting in the formation of specific Ig E in the body 1. It is presumed that some environmental factors play an important role in their clinics. In allergic rhinitis, symptoms usually occur after the interaction of nasal mucosa with allergens. Allergens may be indoors, outdoors or in both environments. House-dust contains most of the indoor allergens. Mites are the most egregious allergen in house dust. D. pteronyssinus is commonly seen in European countries, D. farinae is mostly seen in North America. House-dust mites play an important role in allergic sensitization of individuals in Turkey. Perennial allergic rhinitis is a common chronic disorder that results most frequently from sensitivity to house-dust mites. National and international guidelines for the management of allergic rhinitis recommend that house and dust mite avoidance measures be considered for all patients with house-dust mite provoked rhinitis. Symptoms of allergic rhinitis are related to the environmental mite level in which patients live. The aim of this study is to show the relationship between mite levels and symptoms of allergic rhinitis diagnosed patients and the change of mite levels in the environment after appropriate education
La rinitis alérgica es una enfermedad sobre la que todavía se investiga en todo el mundo. Los alergenos por lo común son de naturaleza glicoproteica o proteica, que interactúan con anticuerpos IgE específicos producidos por el paciente. Se supone que los factores ambientales juegan un papel importante en la clínica. Los síntomas de rinitis alérgica por lo general tienen lugar tras la interacción de la mucosa nasal con los alergenos. Los alergenos pueden ser domiciliarios, del exterior o de ambos ambientes. El polvo de casa contiene muchos de los alergenos domiciliarios. Los ácaros son los alergenos más destacados del polvo doméstico. El D. pteronyssinus es el más común en los países europeos, mientras que el D. farinae es el más abundante en Norte- américa. En Turquía los ácaros del polvo juegan un papel destacado en la sensibilización alérgica. La rinitis alérgica perenne es una enfermedad crónica común debida con más frecuencia a la sensibilización a los ácaros del polvo doméstico. Las guías nacional e internacionales para el tratamiento de la rinitis alérgica recomiendan establecer medidas para evitar los ácaros del polvo doméstico a todos los pacientes con rinitis causada por los ácaros. Los síntomas de rinitis alérgica están relacionados con el nivel de ácaros del ambiente en que vive el paciente. El objetivo de este estudio es mostrar la relación entre el nivel de ácaros y los síntomas en los pacientes diagnosticados de rinitis alérgica y el cambio de la concentración de ácaros en el ambiente después de una educación apropiada
Subject(s)
Male , Female , Humans , Rhinitis/epidemiology , Rhinitis/prevention & control , Acaridae/immunology , Allergens/immunology , Allergens/therapeutic use , Desensitization, Immunologic/methods , Desensitization, Immunologic , Mites , Mites/immunology , Mites/pathogenicity , Environment , Preventive Medicine/education , Preventive Medicine/methods , Preventive Medicine/trendsABSTRACT
We aimed to investigate the incidence and density of Demodex folliculorum in adults with leukaemia or lymphoma. Fifty patients with haematological malignancy and 50 healthy controls were studied. Patients had been diagnosed with acute lymphocytic leukaemia (12%), acute myelocytic leukaemia (32%), chronic lymphocytic leukaemia (4%), chronic myelocytic leukaemia (10%), Hodgkin's lymphoma (4%) or non-Hodgkin's lymphoma (38%). Standardized skin surface biopsies were taken and > or = 5 living parasites/cm2 of skin was defined as an infestation. The difference in infestation rates between patients and controls was statistically significant. The highest incidences of D. folliculorum were found in patients with acute myelocytic leukaemia (10%), non-Hodgkin's lymphoma (6%), acute lymphocytic leukaemia (4%), chronic lymphocytic leukaemia (4%) and chronic myelocytic leukaemia (4%). Demodicidosis should be included in the differential diagnosis of facial eruptions in patients with haematological malignancies who are receiving chemotherapy, and a standardized skin surface biopsy should be performed.
