Lansoprazole as an uncommon cause of anaphylaxis: What to give next?

Proton pump inhibitors (PPIs) are one of the most prescribed drugs worldwide. Anaphylactic reactions of PPIs are rare; however, several cases have been reported. Here, we report a rare case of anaphylaxis that occurred immediately following lansoprazole intake. Following the successful management in the emergency department, skin prick and oral controlled challenge tests were performed to evaluate cross-reactivity. Thereafter, lansoprazole was switched to pantoprazole, which was well tolerated. Skin prick and oral controlled challenge tests can be performed for determining the cross-reactivity of PPIs to prevent adverse reactions.

Comparison of the non-mortal gunshot and handmade explosive blast traumas during a low-intensity conflict on urban terrain.

OBJECTIVES: We aimed to conduct a cross-sectional data analysis involving 60 patients wounded during a low-intensity conflict on urban terrain. MATERIAL AND METHODS: Data of the 60 patients wounded during a low-intensity conflict on urban terrain between September 1st, 2016, and January 15th, 2017, and transferred to our hospital after the initial medical interventions conducted in the regional hospitals were probed retrospectively. Group A consisted of 25 (41.67%) patients suffering gunshot wounds, and Group B consisted of 35 (58.33%) patients with blast trauma injuries. Their Abbreviated Injury Scale scores were compared according to the injured body compartment. RESULTS: In both groups, extremities were the most common site of injury (17 [50%] for Group A, 18 [33.33%] for Group B). The difference between the two groups was statistically significant for only head and neck injuries and facial injuries (p<0.05). In each group, only one body compartment was affected in 19 patients, which represented 55.88% of patients in Group A and 35.18% of patients in Group B. Injuries of three compartments concurrently occurred in 3 (8.82%) patients in Group A and 4 (7.4%) patients in Group B. None of our patients died because of their injuries. CONCLUSION: Contrary to the expected, gunshot casualties were found to be more likely to suffer from extremity injuries than blast casualties did, and it should be noted that blast trauma casualties tend to have multiple compartment injuries that should not be missed. Ocular ruptures are also common, especially with blast injuries, warranting equipping the personnel with protective goggles.

Acute dystonic reaction leading to lingual hematoma mimicking angioedema.

Lingual hematoma is a severe situation, which is rare and endangers the airway. It can develop due to trauma, vascular abnormalities, and coagulopathy. Due to its sudden development, it can be clinically confused with angioedema. In patients who applied to the doctor with complaints of a swollen tongue, lingual hematoma can be confused with angioedema, in particular, at the beginning if the symptoms occurred after drug use. It should especially be considered that dystonia in the jaw can present as drug-induced hyperkinetic movement disorder. Early recognition of this rare clinical condition and taking precautions for providing airway patency are essential. In this case report, we will discuss mimicking angioedema and caused by a bite due to dystonia and separation of the tongue from the base of the mouth developing concurrently with lingual hematoma.

Successful Evaluation of Biphasic T-wave of Wellens Syndrome in the Emergency Department.

INTRODUCTION: Wellens Syndrome (WS) is a condition characterized by typical changes in ECG, which are biphasic T-wave inversions (less common) or symmetric and deeply inverted T waves (including 75%) in lead V2-V3 chest derivations. WS is considered important because it has not only diagnostic value but also prognostic value. CASE REPORT: A 52-year-old male patient without cardiovascular disease or risk factors was admitted to the emergency department (ED) suffering with chest pain and syncope, just after having been involved in a discussion at work. Chest pain was radiating to the left arm and was not precipitated by exertion. Shortness of breath was not accompanied by angina. The patient underwent cardiac catheterization at Department of Cardiology. Stents were positioned in both LADA and a severe lesion in the left main coronary artery. The patient was discharged two days following catheterization, due to no chest pain and hemodynamic instability during the hospitalization. The patient has approved the inform consent for to be used for this case report.