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1.
Arch Environ Occup Health ; 79(2): 107-111, 2024.
Article in English | MEDLINE | ID: mdl-38439586

ABSTRACT

Neurofibromatosis (NF) is a neurocutaneous syndrome characterized by the development of central or peripheral nervous system tumors. The most common form, known as NF1 or Von Recklinghausen's disease, presents with distinct clinical features, including cutaneous and ocular manifestations, along with various other organ and systemic symptoms. While the lung findings associated with neurofibromatosis lack specificity, they can include parenchymal cysts and bullae formation, primarily in the upper-apical regions. Additionally, progressive fibrotic changes, such as ground-glass areas, consolidations, and paving stone patterns, may manifest in the basal parts of the lungs. In this case report, a case of NF1 diagnosed in adulthood and accompanying pneumoconiosis was discussed as a coincidence.


Subject(s)
Neurofibromatosis 1 , Pneumoconiosis , Humans , Neurofibromatosis 1/complications , Male , Pneumoconiosis/etiology , Adult , Middle Aged
2.
Malawi Med J ; 35(4): 220-223, 2023 Dec.
Article in English | MEDLINE | ID: mdl-38362566

ABSTRACT

Background: Tracheobronchial variations (TBVs) are more common than previously believed due to the increasing use of multi-detector computed tomography (MDCT). This study aimed to assess TBVs in cases of pneumoconiosis, one of the oldest occupational diseases that still poses a threat to public health. Methods: This was a descriptive study that involved reviewing chest MDCT images of 34 cases of pneumoconiosis and 34 control cases retrospectively from January 2020 to April 2022. Variations in the trachea, right main bronchus, left main bronchus, lobar and segmental branches of the cases in the patient and control groups were evaluated according to Boyden's nomenclature. Results: The frequency of TBV was 32.4% in pneumoconiosis cases. Although the frequency of TBV was higher in the patient group than in the control group, the difference was not statistically significant (p=0.086). Furthermore, there was no significant difference in terms of TBV classification between the patient and control groups (p=0.407). Additionally, the presence of TBV did not affect the distribution of International Labour Organization categories in pneumoconiosis cases (p=0.360). Conclusions: Although our study provides initial insights into the occurrence of TBVs in pneumoconiosis cases, further research is needed to clarify the relationship between these variations and the disease.


Subject(s)
Occupational Diseases , Pneumoconiosis , Humans , Multidetector Computed Tomography , Retrospective Studies , Pneumoconiosis/diagnostic imaging , Pneumoconiosis/epidemiology , Occupational Diseases/epidemiology , Bronchi
3.
Rev Assoc Med Bras (1992) ; 68(3): 413-416, 2022 Mar.
Article in English | MEDLINE | ID: mdl-35442373

ABSTRACT

OBJECTIVE: The aim of this study was to investigate the frequency of aortic arch anomaly in COVID-19 patients and to determine whether it will be included in the risk classification. METHODS: The study was retrospectively conducted in a third-level hospital by scanning the contrast-enhanced thoracic computed tomography and thoracic computed tomography angiography examinations of patients who received PCR (+), hospitalization, and known COVID pneumonia between March 2020 and July 2021. The study consists of 88 cases and 88 control groups. RESULTS: The study found that the frequency of aortic arch anomaly was higher in patients with COVID-19 pneumonia and in male patients with bovine-type anomaly. CONCLUSIONS: The higher prevalence of bovine arch anomaly in COVID patients may be considered a risk factor for COVID-19 in individuals with this type of vascular anomaly.


Subject(s)
Aorta, Thoracic , COVID-19 , Angiography , Aorta, Thoracic/diagnostic imaging , COVID-19/epidemiology , Humans , Male , Retrospective Studies , Tomography, X-Ray Computed
4.
Rev. Assoc. Med. Bras. (1992, Impr.) ; 68(3): 413-416, Mar. 2022. tab
Article in English | LILACS-Express | LILACS | ID: biblio-1376122

ABSTRACT

SUMMARY OBJECTIVE: The aim of this study was to investigate the frequency of aortic arch anomaly in COVID-19 patients and to determine whether it will be included in the risk classification. METHODS: The study was retrospectively conducted in a third-level hospital by scanning the contrast-enhanced thoracic computed tomography and thoracic computed tomography angiography examinations of patients who received PCR (+), hospitalization, and known COVID pneumonia between March 2020 and July 2021. The study consists of 88 cases and 88 control groups. RESULTS: The study found that the frequency of aortic arch anomaly was higher in patients with COVID-19 pneumonia and in male patients with bovine-type anomaly. CONCLUSIONS: The higher prevalence of bovine arch anomaly in COVID patients may be considered a risk factor for COVID-19 in individuals with this type of vascular anomaly.

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