Brain damage evaluation via arterial spin labeling perfusion imaging for patients with aneurysmal subarachnoid hemorrhage.

OBJECTIVE: Subarachnoid hemorrhage (SAH) is a neurological condition with an annual incidence of 6-22 per 100,000. Despite many advances in diagnosis, the rates of mortality and morbidity in patients remain high. The most important reason for this is complications accompanied by perfusion changes. The aim of our study was to show the perfusion changes with arterial spin labelling (ASL) after SAH. MATERIALS AND METHODS: In this prospective study, 23 patients diagnosed with aneurysmal SAH were evaluated by ASL perfusion imaging between days 1-3 and 8-10. The mean signal intensities (SI) of both hemispheres from the anterior cerebral artery, middle cerebral artery, and basal ganglia were measured manually according to the region of interest. The relationship between the SI values calculated for both cerebral hemispheres, complications, and grading scales of the side with more intense (ipsilateral) and less (contralateral) bleeding were evaluated. RESULTS: There was a significant difference in the ipsilateral/contralateral SI ratio (SIIps/ConBGin) (p = 0.015) among all ASL values, including the basal ganglia between days 0-3 and 8-10. There was a significant negative correlation between ASL parameters and rating scale scores. Additionally, when the SIIps/ConBGinDay0-3 ratio cut-off value was ≤ 0.72, the sensitivity and specificity were 57.1% and 100.0%, respectively, in predicting non-fatal complications, and the sensitivity and specificity in predicting all complications, including death, were 55.6% and 100.0%, respectively. CONCLUSION: Global or regional perfusion decrease can be shown using ASL, with or without the development of vasospasm, without the need for exogenous contrast agent use.

Evaluation of the height of the corpus callosum body region in fetal meningomyelocele malformation.

PURPOSE: To investigate height of the corpus callosum (CC) in order to describe the corpus callosum anomalies in fetuses with meningomyelocele (MMC) and compare these findings with the corpus callosum of healthy fetuses. METHODS: In this study, fetal MRI examinations were performed on 44 fetal MMC malformation cases. As the control group, 34 fetal MRI examinations, which were anatomically normal, were evaluated retrospectively. In the study group, lateral ventricle diameter, the level and diameter of the MMC defect, and CC height were measured. In the control group, CC height and lateral ventricular diameter were measured. RESULTS: The mean CC body height was 1.36 mm in the study group, and 2.48 mm in the control group. The height of the CC body region of the study population was inclined to be thinner compared with the control population (p<0.001). CONCLUSIONS: The fact that the height of the CC body region was found to be thinner in fetal MRI in cases of MMC compared with normal fetuses suggests that various callosal anomalies are uncertain, investigation of additional callosal anomalies may be beneficial in the decision for the continuation of pregnancy, and termination or intrauterine surgery in cases with MMC. Further large case group studies are needed.

Diagnostic performance of multiparametric magnetic resonance imaging in the differentiation of clear cell renal cell cancer.

PURPOSE: This study aimed to evaluate the diagnostic performance of multiparametric magnetic resonance imaging (mpMRI) in the differentiation of renal cell carcinoma (RCC) subtypes. METHODS: This is a retrospective diagnostic performance study, in which the diagnostic performances of mpMRI features were evaluated to differentiate clear cell RCC (ccRCC) from non-clear cell RCC (non-ccRCC). Adult patients who were evaluated using a 3-Tesla dynamic contrast-enhanced mpMRI before undergoing partial or radical nephrectomy for possible malignant renal tumors were included in the study. Signal intensity change percentages (SICP) between contrast-enhanced phases and pre-administration period for both the tumor and normal renal cortex, and tumor-to-cortex enhancement index (TCEI); tumor apparent diffusion coefficient (ADC) values; tumor-to-cortex ADC ratio; and a scale which was developed according to the tumor signal intensities on the axial fat-suppressed T2-weighted Half-Fourier Acquisition Single-shot Turbo spin Echo (HASTE) images were used in ROC analysis to estimate the presence of ccRCC in the patients. The reference test positivity was the histopathologic examination of the surgical specimens. RESULTS: Ninety-eight tumors from 91 patients were included in the study, and 59 of them were ccRCC, 29 were pRCC, and 10 were chRCC. The mpMRI features that had the three highest sensitivity rates were excretory phase SICP, T2-weighted HASTE scale score, and corticomedullary phase TCEI (93.2%, 91.5%, and 86.4%, respectively). However, those with the three highest specificity rates were nephrographic phase TCEI, excretory phase TCEI, and tumor ADC value (94.9%, 94.9%, and 89.7%, respectively). CONCLUSION: Several parameters on mpMRI showed an acceptable performance to differentiate ccRCC from non-ccRCC.

Determination of selected elements in two commercially available edible aquatic insects (Coleoptera) and their worldwide updated list.

Many nations and ethnic groups from underdeveloped and developed countries have used insects as human food since ancient times, a practice that has continued into modern times. In many traditionally entomophagous countries, insects are not a "famine food," and demand for edible insects is clearly a "food of choice" rather than a necessity. From a nutritional point of view, depending on the insect species, gender, insect's diet, and seasons, some species of edible insects have significant amounts of fat, protein, carbohydrates, and vitamins, as well as minerals required for human health, thus representing an alternative food source. In addition to their nutritious content, they may also accumulate pesticide residues, microplastics, and heavy metals from their ecosystems. Therefore, this study analyses some mineral (Ca, Fe, Cu, Zn, Se, Co, Cr, As, and Pb) contents of two selected commercialized aquatic edible beetles, Dytiscus marginalis and Cybister tripunctatus (Dytiscidae), via inductively coupled plasma-mass spectrometry (ICP-MS) and reviews the contemporary list of aquatic edible beetles of the world, summarizing the nutritional characteristics of water beetles with a synthesis of the risks and benefits of edible aquatic beetles in recent literature. The mineral composition of the aquatic beetles is briefly discussed. Antinutritional elements (Pb and As) were detected in aquatic insects, but their contents are below toxic levels for humans. A list of 92 edible aquatic beetle species from Dytiscidae, Gyrinidae, Elmidae, Histeridae, Hydrophilidae, Haliplidae, and Noteridae (Coleoptera) was compiled and updated.

Anthropo-entomophagy: quantitatively chemical assessment of some edible arthropods, bought from an e-shop.

Eating edible arthropods is not associated with rural life anymore. The emerging industry of edible arthropods is trying to change that. The best shopping spot to buy well-known edible arthropods is online today. Consumers can find numerous outlet options to buy edible arthropods from the Internet. With worldwide growing threats to food security, today, gastronomy, especially in western countries, is trying to develop a more positive view to arthropods' nutritional value. In this paper, non-crustacean arthropods (armor tail scorpion, black scorpion, black ant, flying termites, giant waterbug, June beetle, diving beetles, rhino beetles, silkworm pupae, sago worm, bamboo worm), bought from online edible insect market, were evaluated in terms of availability of some hazardous chemical. Energy Dispersive X-Ray Fluorescence (EDXRF) spectroscopy was used for determining the concentrations of heavy metals/metalloids in the total body of the arthropods. Concentration of the elements (Ca, Ti, V, Cr, Mn, Fe, Co, Ni, Cu, Zn, As, Se, Br, Rb, Sr, Pb) were measured quantitatively in all samples. The results showed that the chemicals like Ti, V, Cr, Mn, Fe, Co, Ni, Cu, Zn, As, Se, Br, Rb, Sr, and Pb have highly been measured in the black scorpion, black ant, flying termites, giant waterbug, June beetle, sago worm, and bamboo worm.

Heavy metal accumulation in some aquatic insects (Coleoptera: Hydrophilidae) and tissues of Chondrostoma regium (Heckel, 1843) relevant to their concentration in water and sediments from Karasu River, Erzurum, Turkey.

The objectives of this research were to determine and compare the heavy element concentrations in two study areas in Erzurum, Turkey (Askale and Dumlu sites). Assessment of some heavy elements in sediment, water, fish (Chondrostoma regium) tissues, and some aquatic insects (Coleoptera: Hydrophilidae) were carried out in June to August 2014. Heavy element levels in aquatic insect samples and their associated water and sediment were analyzed by energy dispersive X-ray fluorescence (EDXRF) spectrometer. Fish tissues, from the same habitat, were measured by inductively coupled plasma mass spectrometry (ICP-MS). Eleven elements (Al, Cr, Mn, Fe, Ni, Cu, Zn, As, Cd, Hg, Pb) were measured in fish tissues, and 14 elements (Ti, V, Cr, Mn, Fe, Co, Ni, Cu, Zn, As, Se, Sr, Br, Pb) were measured in insects. According to the results, it can be said that insects were contaminated by water and sediment, thus accumulated higher concentration of some elements than their environment. The fish, which was caught from Askale station, accumulates significantly higher level of heavy metals than Dumlu station's fish. The results were compared with national and international standards. The values of some heavy elements were found at higher concentration than the acceptable limits. The possible consequences of these results are briefly discussed from the point of potential hazards to ecology and human health. Element concentrations in fish tissue are below the limits, which are proposed by Turkish Food Codex, FAO/WHO, and EC, and safe for human consumption in the edible parts of fish species in the regions.

The investigation of heavy element accumulation in some Hydrophilidae (Coleoptera) species.

First of all, this study aimed to find out the measures of some heavy elements (Ti, V, Cr, Mn, Fe, Co, Ni, Cu, Zn, As, Se, Br, Sr, Pb) as heavy element pollution in Erzurum Province, and secondly to observe whether some hydrophilidae (Coleoptera) species can be used as a biomonitor. Insect samples were collected from five different localities of Erzurum in June, July, and August 2014. Heavy element levels in sediment, water, and insect samples were analyzed by energy-dispersive X-ray fluorescence (EDXRF) spectrometer device. According to the results of analysis derived through EDXRF spectrometry, heavy element concentrations display differences between stations and also species. The results pointed out that the insects were contaminated by the sediment and water; therefore, some hydrophilidae species accumulate higher concentration of elements than their environment. Results for levels in water were compared to national water quality guidelines. The values of some heavy elements found at higher concentration than acceptable limits.