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1.
Acta Derm Venereol ; 102: adv00717, 2022 May 19.
Article in English | MEDLINE | ID: mdl-35470404

ABSTRACT

An improved understanding of the impact of skin cancer on patients' daily life may optimize disease management. This questionnaire survey of adult patients in real-world settings aimed to assess patient perception of the diagnosis announcement, and the impact of the diagnosis on the patients' professional and personal life. Data from 355 patients with melanoma and 320 patients with basal cell carcinoma (BCC) were analysed. Melanoma significantly impacted the couple, and sexual relationships, as well as family and social life, and reduced the patient's libido more significantly than did BCC (all p < 0.05). Melanoma and BCC significantly impacted the patients' professional and personal lives. The word "cancer" used for a BCC announcement has a high anxiety-producing meaning for the patient. The announcement of each skin cancer should be made during a dedicated consultation, with more time devoted to the patient and with specific empathy, in order to improve reassurance of the patient.


Subject(s)
Carcinoma, Basal Cell , Carcinoma, Squamous Cell , Melanoma , Skin Neoplasms , Adult , Carcinoma, Basal Cell/diagnosis , Carcinoma, Basal Cell/pathology , Carcinoma, Squamous Cell/pathology , Humans , Melanoma/diagnosis , Melanoma/pathology , Perception , Quality of Life , Skin Neoplasms/diagnosis , Skin Neoplasms/pathology
3.
Anticancer Drugs ; 29(5): 477-481, 2018 06.
Article in English | MEDLINE | ID: mdl-29561309

ABSTRACT

Docetaxel is an antimicrotubules cytotoxic agent prescribed widely by medical oncologists in multiple tumor types (breast, lung, prostate, stomach, head, and neck). However, the side effects of docetaxel are numerous (cytopenia, peripheral edema, myalgia, arthralgia, alopecia, and sensitive neuropathy) and recent concerns have been raised about neutropenic enterocolitis in France. Here, we report the case of a 57-year-old patient with metastatic prostatic cancer, who developed a severe myositis and fasciitis grade IV 1 week after his second docetaxel infusion. We reviewed the five cases of docetaxel-related myositis described in the literature, and found that most of them occurred in patients with diabetes (n=5/5) or hypertension (n=4/5). A vascular toxicity may explain this severe complication, and patients with diabetes or hypertension should be monitored closely in the context of a docetaxel chemotherapy.


Subject(s)
Antineoplastic Agents/adverse effects , Bone Neoplasms/drug therapy , Docetaxel/adverse effects , Myositis/chemically induced , Prostatic Neoplasms, Castration-Resistant/pathology , Bone Neoplasms/secondary , Humans , Male , Middle Aged , Myositis/pathology , Prostatic Neoplasms, Castration-Resistant/therapy
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