Riesgo de enfermedad neumocócica en pacientes ancianos con y sin vacunación previa / Risk of pneumococcal disease in elderly patients with and without previous vaccination

Objetivos: Conocer la cobertura vacunal antineumocócica en pacientes ≥ 65 años, así como el riesgo de enfermedad neumocócica según hayan o no recibido dicha vacunación. Diseño: Estudio transversal, seguido de cohorte histórica. Emplazamiento: Ámbito urbano. Participantes: Se seleccionaron por muestreo sistemático 2.805 personas ≥ 65 años de la ciudad de Albacete. Mediciones principales: Variable dependiente: diagnóstico de enfermedad neumocócica y fecha. Variables independientes: edad, sexo, enfermedades crónicas, medicación, vacunación antineumocócica y fecha. Se revisaron las historias clínicas informatizadas, de 1-1-2009 a octubre-diciembre de 2015. Se ha realizado un análisis descriptivo, se ha calculado el riesgo relativo de aparición de enfermedad neumocócica según la vacunación y se ha realizado un análisis de supervivencia con el programa estadístico SPSS 17.0. Resultados: La mediana de edad era de 71 años; el 57,2% eran mujeres. Recibieron vacuna polisacárida el 46,0% (IC 95% 44,1-47,8). Solo 10 recibieron la conjugada. Fueron diagnosticadas de enfermedad neumocócica invasiva 22 personas, y de no invasiva, 153. El riesgo relativo de enfermedad neumocócica en vacunados frente a no vacunados, respectivamente para invasiva y no invasiva, era 1,59 (IC 95% 0,69-3,68) y 1,84 (IC 95% 1,33-2,54). Por regresión de Cox se demostró un mayor riesgo de enfermedad no invasiva para EPOC (1,95; IC 95% 1,32-2,89), tabaquismo (1,87; IC 95% 1,28-2,73), corticoterapia (1,73; IC 95% 1,08-2,79), vacunación polisacárida (141,41; IC 95% 5,92-3.378,49) y edad (1,11; IC 95% 1,08-1,14), con interacción entre estas 2 (0,94; IC 95% 0,91-0,98). Conclusiones: Existe un mayor riesgo de presentar enfermedad neumocócica en pacientes ≥ 65 años vacunados con la polisacárida, si bien habría que considerar un efecto protector en los vacunados de mayor edad

Objectives: To know the pneumococcal vaccination coverage in patients ≥ 65 years old, as well as the risk of pneumococcal disease according to whether or not they received such vaccination. Design: Cross-sectional study, followed by historical cohort. Location: Urban area. Participants: By systematic sampling, 2,805 people ≥ 65 years from the city of Albacete were selected. Main measurements: Dependent variable: diagnosis of pneumococcal disease and date. Independent variables: age, sex, chronic pathologies, medication, pneumococcal vaccination and date. The computerized medical records were reviewed, from 1-1-2009 to October-December 2015. A descriptive analysis was carried out, the relative risk of the onset of pneumococcal disease according to vaccination has been calculated, and survival analysis has been carried out, with the statistical program SPSS 17.0. Results: Median age 71 years; 57.2% were women; 46% received polysaccharide vaccine (95% CI 44.1-47.8). Only 10 people received conjugated vaccine. Twenty-two people were diagnosed with invasive pneumococcal disease and 153 non-invasive. The relative risk of pneumococcal disease in vaccinated versus unvaccinated, respectively for invasive and non-invasive, was 1.59 (95% CI 0.69-3.68) and 1.84 (95% CI 1.33-2.54). Cox regression showed a higher risk of non-invasive disease for COPD (1.95; 95% CI 1.32-2.89), smoking (1.87; 95% CI 1.28-2.73), corticoid-therapy (1.73; 95% CI 1.08-2.79), polysaccharide vaccination (141.41; 95% CI 5.92-3,378.49) and age (1.11; 95% CI 1.08-1.14), with interaction between these 2 (0.94, 95% CI 0.91-0.98). Conclusions: There is an increased risk of pneumococcal disease in patients ≥ 65 years vaccinated with polysaccharide, although with a protective effect in vaccinated older

Adherencia a la vacunación antigripal de personas mayores tras participar en talleres específicos / Adherence to influenza vaccination among elderly people after participating in specific workshops

Objetivo: Conocer el seguimiento de la vacunación antigripal por ancianos que habían participado en talleres específicos. Diseño: Estudio cuasiexperimental. Emplazamiento: Atención Primaria. Participantes: Se incluyeron 76 personas participantes en talleres sobre gripe y, como controles, 116 que no lo habían hecho. Mediciones Principales: Se comparó el porcentaje de vacunación entre los años 2009 y 2013, según el registro en la historia clínica informatizada. Por análisis de supervivencia se determinó el tiempo de adherencia, considerando "falta de cumplimiento" la primera vez sin vacunar. Resultados: La proporción de vacunados era más alta en los participantes en los talleres: 68,6 % (IC 95 %: 54,9-82,3) vs 61,2 % (IC 95 %: 51,9-70,5) en los que no habían participado, pero sin diferencias estadísticamente significativas (NS). La vacunación se interrumpió en el 45,1 % (IC 95 %: 30,5-59,7) y 42,2 % (IC 95 %: 32,8-51,7), respectivamente, con un cumplimiento medio de 2 años en ambos grupos (NS). Se encontraron diferencias significativas entre ambos grupos para quienes no habiéndose vacunado el año anterior a su inclusión en el estudio, sí lo hacían al año siguiente: 14,9 % vs 5 %, respectivamente para participantes y no participantes en talleres (p < 0,05). Conclusiones: Aunque la asistencia de personas mayores a talleres específicos sobre gripe puede estimular la vacunación inicialmente, no existe una mejora significativa a largo plazo

Objective: To know the adherence to influenza vaccination in elderly people who attended specific workshops. Design: Quasi-experimental study. Location: Primary Care Teams. Participants: 76 people who participated in workshops on influenza, and 116 who did not participate in these workshops used as controls. Main measurements: We compared vaccination percentages between 2009 and 2013, according to data from computerized medical records. A survival analysis was carried out to know how long the patients maintained their vaccination adherence, considering as "non adherence" the first time they were not vaccinated. Results: The proportion of vaccinated patients was higher in those who had participated in the workshops: 68.6 % (95% CI: 54.9-82.3) vs 61.2 % (95% CI: 51.9-70.5), than in those who had not participated, but the differences were not statistically significant (NS). The vaccination was discontinued in 45.1 % (95% CI: 30.5-59.7) and in 42.2 % (95% CI: 32.8-51.7), respectively, with a mean adherence of 2 years in both groups (NS). We found significant differences between both groups in relation to those unvaccinated the year prior to their inclusion in the study who did vaccinate the year after: 14.9 % vs. 5 %, respectively in those who had participated in the workshops and in those who had not participated (p < 0.05). Conclusion: Even though older people's participation in specific workshops on influenza can stimulate influenza vaccination initially, there is no significant long-term improvement

[Risk of pneumococcal disease in elderly patients with and without previous vaccination]. / Riesgo de enfermedad neumocócica en pacientes ancianos con y sin vacunación previa.

OBJECTIVES: To know the pneumococcal vaccination coverage in patients≥65 years old, as well as the risk of pneumococcal disease according to whether or not they received such vaccination. DESIGN: Cross-sectional study, followed by historical cohort. LOCATION: Urban area. PARTICIPANTS: By systematic sampling, 2,805 people≥65 years from the city of Albacete were selected. MAIN MEASUREMENTS: Dependent variable: diagnosis of pneumococcal disease and date. INDEPENDENT VARIABLES: age, sex, chronic pathologies, medication, pneumococcal vaccination and date. The computerized medical records were reviewed, from 1-1-2009 to October-December 2015. A descriptive analysis was carried out, the relative risk of the onset of pneumococcal disease according to vaccination has been calculated, and survival analysis has been carried out, with the statistical program SPSS 17.0. RESULTS: Median age 71 years; 57.2% were women; 46% received polysaccharide vaccine (95% CI 44.1-47.8). Only 10 people received conjugated vaccine. Twenty-two people were diagnosed with invasive pneumococcal disease and 153 non-invasive. The relative risk of pneumococcal disease in vaccinated versus unvaccinated, respectively for invasive and non-invasive, was 1.59 (95% CI 0.69-3.68) and 1.84 (95% CI 1.33-2.54). Cox regression showed a higher risk of non-invasive disease for COPD (1.95; 95% CI 1.32-2.89), smoking (1.87; 95% CI 1.28-2.73), corticoid-therapy (1.73; 95% CI 1.08-2.79), polysaccharide vaccination (141.41; 95% CI 5.92-3,378.49) and age (1.11; 95% CI 1.08-1.14), with interaction between these 2 (0.94, 95% CI 0.91-0.98). CONCLUSIONS: There is an increased risk of pneumococcal disease in patients≥65 years vaccinated with polysaccharide, although with a protective effect in vaccinated older.

Eficacia de una estrategia combinada para mejorar el control del colesterol unido a lipoproteínas de baja densidad en pacientes con hipercolesterolemia. Ensayo clínico aleatorizado / Efficacy of a combined strategy to improve low-density lipoprotein cholesterol control among patients with hypercholesterolemia: a randomized clinical trial

Introducción y objetivos: Intervenciones diferentes pueden mejorar el control del colesterol unido a lipoproteínas de baja densidad (cLDL). El objetivo principal era evaluar la eficacia de una intervención combinada para mejorar el control del cLDL de pacientes con hipercolesterolemia. También se evaluó su eficacia para mejorar el cumplimiento (farmacológico, dieta y ejercicio). Métodos: Ensayo clínico aleatorizado, de grupos paralelos y multicéntrico (atención primaria) que incluyó a 358 adultos diagnosticados de hipercolesterolemia con tratamiento previo farmacológico o no. Se comparó a 178 sujetos que recibieron intervención combinada (material escrito, tarjetas autocumplimentadas y mensajes al móvil) frente a 178 controles. La variable principal de resultado fue la proporción de sujetos con adecuado control del cLDL (valores recomendados en las guías europeas de dislipemias y riesgo cardiovascular) a los 24 meses. Resultados: El grupo de intervención mostró una reducción media del cLDL significativamente superior a los 24 meses respecto al control, 23,8 mg/dl (IC95%, 17,5-30,1) y 14,6 mg/dl (IC95%, 8,9-20,4), respectivamente (p = 0,034). El promedio de la reducción del cLDL fue del 13,1 ± 28,6%. La proporción de sujetos con adecuado control al año fue significativamente superior en el grupo de intervención (43,7 frente a 30,1%; p = 0,011; RR = 1,46). En el grupo de intervención, el cumplimiento farmacológico fue significativamente superior (77,2 frente a 64,1%; p = 0,029) y de la práctica de ejercicio (64,9 frente a 35,8%; p < 0,001), aunque no de la dieta. Conclusiones: La intervención combinada consigue una reducción significativa de las cifras de cLDL (superior al 13% al cabo de 2 años) y mejora el grado de control de pacientes con hipercolesterolemia al año (AU)

Introduction and objectives: Several interventions can improve low-density lipoprotein cholesterol (LDL-C) control. Our main objective was to evaluate the efficacy of a combined intervention to improve LDL-C control in patients with hypercholesterolemia. The study also assessed the efficacy of the intervention in improving adherence (pharmacological, diet, and exercise). Methods: A multicenter, parallel group, randomized clinical trial (primary care) was conducted in 358 adults diagnosed with hypercholesterolemia, whether receiving prior drug therapy or not. We compared 178 participants who received the combined intervention (written material, self-completed registration cards, and messages to mobile telephones) with 178 controls. The main outcome variable was the proportion of participants with adequate LDL-C control (target levels of the European guidelines on dyslipidemia and cardiovascular risk) at 24 months. Results: At 24 months, the mean reduction in LDL-C was significantly higher in the intervention group (23.8 mg/dL [95%CI, 17.5-30.1]) than in the control group (14.6 mg/dL [95%CI, 8.9-20.4]; P = .034). The mean LDL-C decrease was 13.1% ± 28.6%. At 1 year, the proportion of participants with adequate control was significantly higher in the intervention group than in the control group (43.7% vs 30.1%; P = .011; RR, 1.46). Adherence was significantly higher in the intervention group, both to drug therapy (77.2% vs 64.1%; P = .029) and exercise (64.9% vs 35.8; P < .001), but not to diet. Conclusions: The combined intervention significantly reduced LDL-C (by more than 13% at 2 years) and improved the degree of LDL-C control in patients with hypercholesterolemia at 1 year (AU)

Efficacy of a Combined Strategy to Improve Low-density Lipoprotein Cholesterol Control Among Patients With Hypercholesterolemia: A Randomized Clinical Trial.

INTRODUCTION AND OBJECTIVES: Several interventions can improve low-density lipoprotein cholesterol (LDL-C) control. Our main objective was to evaluate the efficacy of a combined intervention to improve LDL-C control in patients with hypercholesterolemia. The study also assessed the efficacy of the intervention in improving adherence (pharmacological, diet, and exercise). METHODS: A multicenter, parallel group, randomized clinical trial (primary care) was conducted in 358 adults diagnosed with hypercholesterolemia, whether receiving prior drug therapy or not. We compared 178 participants who received the combined intervention (written material, self-completed registration cards, and messages to mobile telephones) with 178 controls. The main outcome variable was the proportion of participants with adequate LDL-C control (target levels of the European guidelines on dyslipidemia and cardiovascular risk) at 24 months. RESULTS: At 24 months, the mean reduction in LDL-C was significantly higher in the intervention group (23.8mg/dL [95%CI, 17.5-30.1]) than in the control group (14.6mg/dL [95%CI, 8.9-20.4]; P=.034). The mean LDL-C decrease was 13.1%±28.6%. At 1 year, the proportion of participants with adequate control was significantly higher in the intervention group than in the control group (43.7% vs 30.1%; P=.011; RR, 1.46). Adherence was significantly higher in the intervention group, both to drug therapy (77.2% vs 64.1%; P=.029) and exercise (64.9% vs 35.8; P<.001), but not to diet. CONCLUSIONS: The combined intervention significantly reduced LDL-C (by more than 13% at 2 years) and improved the degree of LDL-C control in patients with hypercholesterolemia at 1 year.

Frecuencia y características de uso de Internet por adolescentes espanoles: Un estudio transversal / Frequency and characteristics of Internet use by Spanish teenagers: A cross-sectional study

Introducción: Internet ha transformado la comunicación entre las personas en el mundo actual, especialmente en el caso de los más jóvenes. El objetivo de este estudio es determinar la frecuencia de uso de Internet por adolescentes, así como las aplicaciones utilizadas. Población y métodos: Se trata de un estudio transversal. En noviembre de 2013, los estudiantes de la escuela secundaria obligatoria de dos institutos de Albacete fueron invitados a responder un cuestionario autoadministrable, con preguntas de respuesta abierta y cerrada. Contestaron en las aulas, "on line" o con "lápiz y papel". Las respuestas fueron introducidas en una base de datos informatizada, con el programa SPSS 17.0. El análisis estadístico ha incluido comparación de proporciones (chi cuadrado) y de medias/medianas (t de Student/pruebas no paramétricas). Resultados: Participaron 967 estudiantes, con media de edad de 13,8 años (rango: 11-20); 53,5% de mujeres. La mayoría (70,9%) vivían en la ciudad. La clase social era mayoritariamente media (51,3%) y alta (34,8%). La mayoría se conectaba a Internet a diario (73,4%); solo 0,9% decía no conectarse nunca. Las aplicaciones más utilizadas eran WhatsApp (77,1%), redes sociales (70,1%) y relacionadas con música (66,6%). Se ha encontrado una mayor frecuencia de utilización por las mujeres de redes sociales (p= 0,004), WhatsApp (p <0,0001), Instagram (p <0,0001) y escuchar música (p= 0,004). Los varones navegaban más (p <0,0001), utilizaban Skype (p= 0,001), jugaban (p <0,0001) y veían películas o series (p= 0,035). Conclusiones: Internet ocupa una gran parte del tiempo de los adolescentes, especialmente como medio de comunicación, y WhatsApp y las redes sociales son las aplicaciones que utilizan con más frecuencia.

Introduction. Internet has completely changed communication among people in today's world, especially among young users. The objective of this study is to establish the frequency of Internet use by teenagers, and most used apps. Population and methods. This was a crosssectional study. In November 2013, students attending two mandatory secondary schools in Albacete were invited to complete a self-administered questionnaire with close-ended and open questions. Questionnaires were completed in the classroom, either "online" or "with pen and paper". Answers were entered in a computer database using the SPSS 17.0 software. Statistical analysis included a comparison of proportions (χ2 test) and mean/median values (Student's t test/non-parametric tests). Results. Nine hundred and sixty-seven students participated; their mean age was 13.8 years old (range: 11-20); 53.5% were girls. Most students (70.9%) lived in the city. Most belonged to a middle (51.3%) and high (34.8%) socioeconomic status. Also most students went online on a daily basis (73.4%); only 0.9% indicated that they never did. The most frequently used apps included WhatsApp (77.1%), social networks (70.1%) and music apps (66.6%). Among girls, the most common Internet use was social networks (p= 0.004), WhatsApp (p < 0.0001), Instagram (p < 0.0001) and listening to music (p= 0.004). Boys most commonly used the Internet to browse the web (p < 0.0001), Skype (p=0.001), play (p < 0.0001) andwatchmovies or TV shows (p= 0.035). Conclusions. Internet takes up a large part of the time in adolescents' lives, especially as a means of communications, being WhatsApp and social networks the most commonly used apps.

Talleres sobre problemas de salud prevalentes con personas integradas en grupos de trabajo en centros de mayores / Workshops on prevalent health issues with people involved in working groups in centres for the elderly

Objetivo: Evaluar cambios en conocimientos de personas mayores que participan en talleres sobre temas de salud. Diseño del estudio: Estudio “antes-después”. Emplazamiento: Comunitario. Participantes: Personas integradas en grupos de trabajo en dos centros de mayores. Intervención: Se programaron intervenciones educativas sobre gripe, osteoporosis y riesgo cardiovascular (RCV). Previo consentimiento informado, los participantes contestaron un cuestionario de conocimientos, datos sociodemográficos y estado general de salud. A continuación se exponía el tema por uno de los miembros del grupo investigador. Se terminaba con un cuestionario postest. Mediciones principales: Variables sociodemográficas, de conocimientos sobre los temas tratados y estado general de salud. Resultados: En el taller sobre gripe participaron 24 personas. Antes del taller 45,8 % conocían los síntomas, 25 % decía que conocía la prevención; después el 58,3 % (NS) y el 70,8 % (p=0,001), respectivamente. En el de osteoporosis participaron 37. Antes del taller, 59,5 % decía conocer algo sobre osteoporosis, y 89,2 % sabían que afecta a los huesos. Conocían la importancia de consumir lácteos 75,7 %. Tras el taller se planteaban cambios: alimentación (13,5 %), ejercicio (18,9 %), visitas a su médico (27 %), varios aspectos (13,5 %). En el de RCV participaron 19. Antes del taller, 57,9 % había oído sobre factores de RCV, aunque 84,2 % no sabía nombrarlos. Tras el taller se redujo en un 50 % las personas que no sabían dar el nombre de algún factor de RCV (p=0,021). Conclusiones: Los conocimientos de las personas participantes en los talleres mejoraban después de los mismos, para los diferentes temas tratados (AU)

Objective: To evaluate changes in knowledge of elderly people who take part in workshops on health issues. Study Design: Before and after study. Participants: People involved in working groups in two centres for the elderly. Procedure: Educational interventions about influenza, osteoporosis, and cardiovascular risk were programmed. Subject to prior informed consent, the participants answered a questionnaire about previous knowledge, sociodemographic data, and overall health. Then, one of the members of the research group explained a subject. To conclude, a post-test questionnaire was completed. Main measurements: Variables related to sociodemographic features, knowledge of the topics discussed, and overall health. Results: 24 people took part in the workshop on influenza. Before the workshop, 45,8% knew the symptoms, 25% said they knew about its prevention. After the workshop, 58,3% (NS) and 70,8% (p=0,001), respectively. Conclusions: People participating in the workshops improved their knowledge of the topics Discussed (AU)

[Variability in the control of oral anticoagulant therapy between primary care and hospital in Albacete (2009)]. / Variabilidad en los controles de la terapia anticoagulante oral entre atención primaria y hospital en Albacete (2009).

BACKGROUND: After taking control of oral anticoagulant therapy in our health center it became necessary to detect possible differences with regard to hospital monitoring. The aim of our study was to determine the variability in the International Normalized Ratio (INR) values of patients on oral anticoagulant therapy (OAT), and the possible relation to control in primary care or hospital. METHODS: We analyzed the last 6 controls of 291 patients in an urban health centre in routine control by OAT. In order to analyze the variability, we calculated the standard deviation (SD) of natural logarithm (ln) of INR values, comparing by Student t test their mean between patients whose treatment had been scheduled in primary care and those on some occasions ruled by them and others in hospital. We compared also the proportion of controls within range in each group (chi2). RESULTS: 153 (52.6%) patients were women, and the mean age was 73.8 years (SD: 11.3). We analyzed a total of 1710 INR controls, of which 1412 have been validated by family physicians and 298 by haematologists; there were no significant differences in INR values. Patients whose treatment had been scheduled by professionals of the health centre had mean values of the SD of the ln of the INR of 6 controls analyzed significantly lower (p <0.0001) than in those who had taken a mixed control. Also, a higher proportion of controls within range (68.0% vs 38.6%, p <0.0001). CONCLUSIONS: Patients who are followed only by professionals in the health centre have less variability and more appropriate INR control than those with a mixed control health centre / hospital.

Variabilidad en los controles de la terapia anticoagulante oral entre Atención Primaria y Hospital en Albacete (2009) / Variability in the control of oral anticoagulant therapy between primary care and Hospital in Albacete (2009)

Fundamento: Tras asumir el control de la terapia anticoagulante oral en nuestro centro de salud surgió la necesidad de detectar posibles diferencias con respecto al seguimiento hospitalario. El objetivo de nuestro trabajo fue conocer la variabilidad en los valores del Cociente Normalizado Internacional (INR) de los pacientes en tratamiento anticoagulante oral (TAO), y su posible relación con el control en centro de salud u hospital. Métodos: Se analizaron los 6 últimos controles de 291 pacientes de un centro de salud urbano en control rutinario por TAO. A fin de analizar su variabilidad, se ha calculado la desviación estándar (DE) de los logaritmos neperianos (ln) de los valores de INR, comparando por medio del test t de Student la media de las mismas entre aquellos pacientes cuyo tratamiento había sido pautado por profesionales del centro de salud y aquellos pautados en unas ocasiones por éstos y en otras en hospital. Se comparó asimismo la proporción de controles dentro de rango en cada grupo (chi2). Resultados: Eran mujeres 153 (52,6%) de los pacientes, y la media de edad era 73,8 años (DE: 11,3). Se han analizado un total de 1.710 controles de INR, de los que 1.412 han sido validados por médicos de familia y 298 por hematólogos, sin que existieran diferencias significativas en los valores de INR analizados por unos y otros. Los pacientes cuyo tratamiento había sido pautado siempre por profesionales del centro de salud presentaron unos valores medios de DE de los ln de los INR de los 6 controles analizados significativamente inferior (p<0,0001) al de aquellos que habían llevado un control mixto. Asimismo, presentaban una mayor proporción de controles dentro de rango (un 68,0% vs 38,6%; p<0,0001). Conclusiones: Los pacientes que son seguidos exclusivamente por los profesionales del centro de salud presentan una menor variabilidad y más adecuados controles de INR que aquellos con un control mixto centro de salud/hospital(AU)

Background: After taking control of oral anticoagulant therapy in our health center it became necessary to detect possible differences with regard to hospital monitoring. The aim of our study was to determine the variability in the International Normalized Ratio (INR) values of patients on oral anticoagulant therapy (OAT), and the possible relation to control in primary care or hospital. Methods: We analyzed the last 6 controls of 291 patients in an urban health centre in routine control by OAT. In order to analyze the variability, we calculated the standard deviation (SD) of natural logarithm (ln) of INR values, comparing by Student t test their mean between patients whose treatment had been scheduled in primary care and those on some occasions ruled by them and others in hospital. We compared also the proportion of controls within range in each group (chi2). Results: 153 (52.6%) patients were women, and the mean age was 73.8 years (SD: 11.3). We analyzed a total of 1710 INR controls, of which 1412 have been validated by family physicians and 298 by haematologists; there were no significant differences in INR values. Patients whose treatment had been scheduled by professionals of the health centre had mean values of the SD of the ln of the INR of 6 controls analyzed significantly lower (p <0.0001) than in those who had taken a mixed control. Also, a higher proportion of controls within range (68.0% vs 38.6%, p <0.0001). Conclusions: Patients who are followed only by professionals in the health centre have less variability and more appropriate INR control than those with a mixed control health centre / hospital(AU)

Cinco preguntas clave en la gripe: una revisión de guías / Five key questions on flu: a review of the guidelines

La gripe es una enfermedad infecciosa aguda provocada por el virus de la influenza A, B y C, que afecta principalmente al aparato respiratorio, se transmite con gran facilidad por secreciones y objetos contaminados, presenta riesgo potencial de complicaciones, especialmente en grupos susceptibles, y es una de las causas más frecuentes de absentismo laboral. Con el objetivo de actualizar el abordaje del síndrome gripal y recopilar información que ayude al clínico en la toma de decisiones, revisamos las recomendaciones presentadas en diferentes guías de práctica clínica. Realizamos una búsqueda en las bases bibliográficas habitualmente utilizadas en el ámbito internacional seleccionando las que sustentan sus recomendaciones en niveles de evidencia y han sido actualizadas en los tres últimos años. Decidimos incluir otras guías que no mencionan niveles de evidencia pero están avaladas por sociedades científicas o instituciones de prestigio internacional. Comparamos las recomendaciones presentadas en cinco aspectos clave: diagnóstico, manejo en los centros sanitarios, tratamiento, consejos e información a la población y vacunación (AU)

Flu is an acute infectious disease caused by the viruses A, B and C. It mainly affects the respiratory system and is easily transmitted by secretions and contaminated objects. It has a potential risk of complications, especially in susceptible groups, and is one of the most common causes of work absenteeism. With the aim of updating flu management and collecting information that will help the doctor in decision making, we reviewed the recommendations given in different clinical practice guidelines. We searched the bibliographical databases commonly used internationally and chose those guidelines that based their recommendations on levels of evidence and that had been updated in the last three years. We decided to include other guidelines that do not mention levels of evidence but that are endorsed by internationally renowned scientific societies or institutions. We compared the recommendations given according to five key elements: diagnosis, management in health centres, treatment, advice and information to the general public and vaccination (AU)

“Si llevas el Anillo conéctate a la Web”: Análisis de las opiniones encontradas en foros de Internet sobre el uso del Anillo Anticonceptivo Vaginal / “If you use the Ring get on line”: Analysis of the opinions on the use of the Vaginal Contraceptive Ring found on Internet forums

Objetivos. Conocer las opiniones acerca del uso del anillo anticonceptivo vaginal expresadas en foros de Internet. Diseño del estudio. Estudio cualitativo. Emplazamiento. Atención comunitaria. Participantes. Participantes en foros de Internet relacionados con el uso del anillo vaginal. Mediciones y Resultados. Por medio de una búsqueda en Google se identificaron foros en los que sehiciera referencia al uso del anillo vaginal. Se han revisado 85 foros, seleccionando opiniones de 246participantes. Seguidamente se clasificó y sintetizó la información recogida. Como ventajas más relevantes se han destacado: comodidad de administración, no suele haberolvidos, regula el ciclo menstrual, no produce aumento de peso, su eficacia no se afecta por vómitoso diarreas, y se evita el primer paso de metabolismo hepático. Entre los inconvenientes habría que resaltar: sensación de que se va a salir, precio, algunas mujeres se quejan de irregularidad menstrual ,irritación vaginal, sensibilidad mamaria, aumento de peso, cambios de humor, cefalea, menos flujovaginal, náuseas, cansancio, e interacciones medicamentosas. Se subrayan también inconvenientes en relación con la aplicación del dispositivo, el modo de conservación o cuándo empieza a ser efectivo. Las opiniones sobre cómo afecta a las relaciones sexuales oscilan entre quienes consideran que aumenta la libido y quienes refieren una disminución del deseo sexual, o bien molestias en las relaciones, debido a que la pareja o las usuarias lo notan. Conclusiones. El anillo vaginal es un método anticonceptivo fácil de utilizar, cómodo de aplicar y seguro, sin embargo, presenta frecuentes efectos adversos sobre todo a nivel local (AU)

“If you use the Ring get on line”: Analysis of the opinions on the use of the Vaginal Contraceptive Ring found on Internet forums Objectives. To learn the opinions on the use of the vaginal contraceptive ring expressed on Internet forums. Study design. Qualitative study Setting. Community healthcare. Participants. Participants on internet forums related to the use of vaginal rings. Measurements and Results. A search on Google identified forums that referred to the use of the vaginal ring. A total of 85 forums were reviewed, and opinions from 246 participants were selected. The information was then classified and summarised. The most significant advantages pointed out were: easy to use, not easily forgotten, regulates menstrual cycle, doesn’t cause weight gain, its effi cacy is not affected by vomiting or diarrhea, it avoids first pass hepatic metabolism. Amongst the disadvantages pointed out were: feeling that it is going to slip out, some women complained of irregular periods, vaginal irritation, breast tenderness, weight gain, nausea, mood swings, headache, vaginal dryness, nausea, tiredness and drug interactions. Other drawbacks related to the insertion of the ring, how to store it or when it becomes effective, were emphasised. Opinions on how it affected sexual relations ranged from increased libido to a decrease in sexual desire, or the user or user’s partner can feel it during sexual intercourse. Conclusions. The vaginal ring is an easy to use contraceptive method, easy to insert and safe. However there are frequent adverse effects especially local effects (AU)

Cefalea Cardiaca / Cardiac headache

El diagnóstico diferencial entre cefalea primaria y secundaria y sus diferentes subtipos se basa en lahistoria clínica y en la exploración física. Éstos permiten detectar si la cefalea presenta síntomas dealarma y cuáles son sus características para establecer un diagnóstico apropiado de acuerdo con los criterios diagnósticos de la IHSII (The Internacional Clasifi cation of Headache Disorders, segunda edición). La entrevista clínica es nuestra principal herramienta para la detección, diagnóstico y atención acerca de las quejas somáticas relatadas por nuestros pacientes. Presentamos el caso de una paciente diagnosticada de cefalea cardiaca

The differential diagnosis between primary and secondary headache and its different subtypes is based on the clinical history and the physical exploration. These can detect whether the headache presents warning signs and which characteristics can establish an appropriate diagnosis according to the diagnostic criteria of the IHSII (The International Classifi cation of Headache Disorders, second edition). The clinical interview is our main tool to detect, diagnose and treat the somatic complaints reported by our patients. We present the case of a patient diagnosed with cardiac headache