ABSTRACT
Functional dyspepsia is a common gastric disease that can be associated with Helicobacter pylori infection. The aim of this study is to evaluate antral endoscopy of individuals who presented with functional dyspepsia, H. pylori infection status and the effects of eradication therapy on the symptoms. Following the diagnosis of dyspepsia as per Rome III criteria, 260 individuals who were eligible for the study underwent upper gastrointestinal endoscopy and were divided into four groups of 65 according to the endoscopic view, grades I, II, III and IV (negative). Stool antigen test was also performed for all patients to identify H. pylori infection. The early signs of dyspepsia were assessed by a standard questionnaire. In all groups, omeprazole, amoxicillin, clarithromycin and metronidazole were used for eradication treatment, and 1 month after the treatment, a faecal antigen test was repeated to evaluate the eradication of H. pylori. There was no statistically significant difference between the groups in terms of clinical symptoms before treatment. The highest response to eradication treatment was seen in individuals with antral gastropathy grade III (66.2%) and the lowest response was in patients without antral gastropathy Grade IV (32.3%). This difference was statistically significant. There was no statistically significant relationship between the participants in terms of family history, age, gender and response to treatment. Eradicating H. pylori reduces the symptoms of dyspepsia. The response of eradication therapy was greatest among the patients with grade III antral gastropathy.
ABSTRACT
Two experiments were conducted to investigate the effect of supplemental bentonite on performance, blood, and fermentation characteristics in Zandi lambs. In experiment 1, 20 Zandi male lambs (initial BW, 17.5 ± 1.6 kg and 110 ± 5 days old) were randomly assigned into four groups of five animals in each. The experimental treatments were (1) control (no Pb and bentonite), (2) 15 mg/kg DM Pb as Pb acetate and no bentonite, (3) 15 mg/kg DM Pb as Pb acetate and 1.5% bentonite, and (4) 15 mg/kg DM Pb as Pb acetate and 3% bentonite. The dietary treatments had no significant effect on dry matter intake of experimental lambs. Feed required per unit of weight gain was more (P < 0.05) in lead-exposed lambs in group 2 compared to the control and bentonite supplemented groups. Serum glucose, urea nitrogen, cholesterol, HDL, and LDL concentrations was similar among the treatments. In experiment 2, an in vitro gas production technique was used to evaluate the effects of bentonite supplementation on the gas production parameters of lead-polluted diets. The rate and amount of gas production was higher for bentonite supplemented groups (P < 0.01). Asymptotic gas production (b), metabolizable energy, and concentration of short chain fatty acids were lower (P < 0.05) for lead-polluted non-supplemented diet (group 2) as compared to the bentonite supplemented and control groups. It was concluded that bentonite supplementation favorably modified ruminal fermentation pattern and improved feed conversion ratio in growing lead-exposed lambs.
