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1.
Obes Res Clin Pract ; 18(3): 195-200, 2024.
Article in English | MEDLINE | ID: mdl-38955573

ABSTRACT

INTRODUCTION: Revisional bariatric surgery (RBS) for insufficient weight loss/weight regain or metabolic relapse is increasing worldwide. There is currently no large multinational, prospective data on 30-day morbidity and mortality of RBS. In this study, we aimed to evaluate the 30-day morbidity and mortality of RBS at participating centres. METHODS: An international steering group was formed to oversee the study. The steering group members invited bariatric surgeons worldwide to participate in this study. Ethical approval was obtained at the lead centre. Data were collected prospectively on all consecutive RBS patients operated between 15th May 2021 to 31st December 2021. Revisions for complications were excluded. RESULTS: A total of 65 global centres submitted data on 750 patients. Sleeve gastrectomy (n = 369, 49.2 %) was the most common primary surgery for which revision was performed. Revisional procedures performed included Roux-en-Y gastric bypass (RYGB) in 41.1 % (n = 308) patients, One anastomosis gastric bypass (OAGB) in 19.3 % (n = 145), Sleeve Gastrectomy (SG) in 16.7 % (n = 125) and other procedures in 22.9 % (n = 172) patients. Indications for revision included weight regain in 615(81.8 %) patients, inadequate weight loss in 127(16.9 %), inadequate diabetes control in 47(6.3 %) and diabetes relapse in 27(3.6 %). 30-day complications were seen in 80(10.7 %) patients. Forty-nine (6.5 %) complications were Clavien Dindo grade 3 or higher. Two patients (0.3 %) died within 30 days of RBS. CONCLUSION: RBS for insufficient weight loss/weight regain or metabolic relapse is associated with 10.7 % morbidity and 0.3 % mortality. Sleeve gastrectomy is the most common primary procedure to undergo revisional bariatric surgery, while Roux-en-Y gastric bypass is the most commonly performed revision.


Subject(s)
Bariatric Surgery , Reoperation , Weight Loss , Humans , Female , Male , Reoperation/statistics & numerical data , Bariatric Surgery/methods , Bariatric Surgery/mortality , Bariatric Surgery/adverse effects , Middle Aged , Adult , Prospective Studies , Postoperative Complications/mortality , Postoperative Complications/etiology , Postoperative Complications/epidemiology , Obesity, Morbid/surgery , Obesity, Morbid/mortality , Gastric Bypass/methods , Gastric Bypass/mortality , Gastric Bypass/adverse effects , Gastrectomy/methods , Gastrectomy/adverse effects , Weight Gain , Morbidity
4.
Langenbecks Arch Surg ; 408(1): 302, 2023 Aug 09.
Article in English | MEDLINE | ID: mdl-37555850

ABSTRACT

BACKGROUND: Comparative data on D2-robotic gastrectomy (RG) vs D2-open gastrectomy (OG) are lacking in the Literature. Aim of this paper is to compare RG to OG with a focus on D2-lymphadenectomy. STUDY DESIGN: Data of patients undergoing D2-OG or RG for gastric cancer were retrieved from the international IMIGASTRIC prospective database and compared. RESULTS: A total of 1469 patients were selected for inclusion in the study. After 1:1 propensity score matching, a total of 580 patients were matched and included in the final analysis, 290 in each group, RG vs OG. RG had longer operation time (210 vs 330 min, p < 0.0001), reduced intraoperative blood loss (155 vs 119.7 ml, p < 0.0001), time to liquid diet (4.4 vs 3 days, p < 0.0001) and to peristalsis (2.4 vs 2 days, p < 0.0001), and length of postoperative stay (11 vs 8 days, p < 0.0001). Morbidity rate was higher in OG (24.1% vs 16.2%, p = 0.017). CONCLUSION: RG significantly expedites recovery and reduces the risk of complications compared to OG. However, long-term survival is similar.


Subject(s)
Laparoscopy , Robotic Surgical Procedures , Stomach Neoplasms , Humans , Propensity Score , Gastrectomy , Lymph Node Excision , Stomach Neoplasms/surgery , Treatment Outcome , Retrospective Studies , Postoperative Complications/epidemiology , Postoperative Complications/surgery
7.
Ann Surg Oncol ; 30(3): 1500-1503, 2023 Mar.
Article in English | MEDLINE | ID: mdl-36335270

ABSTRACT

INTRODUCTION: In the past decade, minimally invasive pancreaticoduodenectomy has been gaining interest. However, minimally invasive pancreaticoduodenectomy remains technically challenging and is associated with a steep learning curve. Additionally, the operating surgeon should be cognizant of replicating the same oncological steps as observed in the typical open approach. In view of this, there exist various maneuvers that are designed to achieve negative margins and a safer mesopancreatic dissection. One of these techniques is the superior mesenteric artery first approach, which is garnering interest among pancreatic surgeons. MATERIAL AND METHODS: According to existing literature, there are several superior mesenteric artery dissections approaches. We describes 5 different minimally invasive approaches. RESULTS: This multimedia manuscript provide, for the first time in literature, a comprehensive step-by-step overview of the superior mesenteric artery first approach for minimally invasive pancreaticoduodenectomy by a team of expert surgeons from various international institutions. CONCLUSIONS: Through the tips and indications presented in this article, we aim to guide the choice of this approach according to tumor location, type of minimally invasive approach and the operating surgeon's experience and increase familiarity with such a complex procedure.


Subject(s)
Laparoscopy , Pancreatic Neoplasms , Humans , Anastomosis, Surgical , Laparoscopy/methods , Mesenteric Artery, Superior/surgery , Pancreatectomy , Pancreatic Neoplasms/surgery , Pancreaticoduodenectomy/methods
10.
Updates Surg ; 75(1): 255-259, 2023 Jan.
Article in English | MEDLINE | ID: mdl-36371550

ABSTRACT

Minimally invasive pancreaticoduodenectomy (PD) is attracting increased interest in the pancreatic surgical community with more and more teams reporting their experience worldwide. The pancreatic anastomosis (PA) is one of the key steps and challenging manoeuvre of this procedure. Since the introduction of the minimally invasive approach for PD, several PA types have been proposed, ranging from high to low complexity, but none of them have been proven unequivocally superior to the others. Therefore, definitive consensus has not been reached yet. In the present multimedia manuscript, we report the most commonly adopted minimally invasive PA and we propose a "complexity classification" to guide the choice accordingly to different characteristics of the pancreatic stump. We describe five possible different PA that might be tailored to each different case, depending mainly on texture of pancreatic stump (soft/hard, lean/fatty) and the size and visibility of main duct. This manuscript presents a step-by-step portfolio of the most commonly used mini-invasive PA. This technique requires experience in pancreatic surgery and advanced minimally invasive skills. Knowledge of and proficiency in different types of PA could help reducing the incidence of postoperative pancreatic fistula.


Subject(s)
Pancreas , Pancreaticoduodenectomy , Humans , Pancreaticoduodenectomy/methods , Pancreas/surgery , Pancreatectomy , Pancreatic Fistula/etiology , Pancreatic Fistula/prevention & control , Anastomosis, Surgical/methods , Postoperative Complications/epidemiology
12.
Cancers (Basel) ; 13(18)2021 Sep 08.
Article in English | MEDLINE | ID: mdl-34572753

ABSTRACT

BACKGROUND: The laparoscopic approach in gastric cancer surgery is being increasingly adopted worldwide. However, studies focusing specifically on laparoscopic gastrectomy with D2 lymphadenectomy are still lacking in the literature. This retrospective study aimed to compare the short-term and long-term outcomes of laparoscopic versus open gastrectomy with D2 lymphadenectomy for gastric cancer. METHODS: The protocol-based, international IMIGASTRIC (International study group on Minimally Invasive surgery for Gastric Cancer) registry was queried to retrieve data on patients undergoing laparoscopic or open gastrectomy with D2 lymphadenectomy for gastric cancer with curative intent from January 2000 to December 2014. Eleven predefined, demographical, clinical, and pathological variables were used to conduct a 1:1 propensity score matching (PSM) analysis to investigate intraoperative and recovery outcomes, complications, pathological findings, and survival data between the two groups. Predictive factors of long-term survival were also assessed. RESULTS: A total of 3033 patients from 14 participating institutions were selected from the IMIGASTRIC database. After 1:1 PSM, a total of 1248 patients, 624 in the laparoscopic group and 624 in the open group, were matched and included in the final analysis. The total operative time (median 180 versus 240 min, p < 0.0001) and the length of the postoperative hospital stay (median 10 versus 14.8 days, p < 0.0001) were longer in the open group than in the laparoscopic group. The conversion to open rate was 1.9%. The proportion of patients with in-hospital complications was higher in the open group (21.3% versus 15.1%, p = 0.004). The median number of harvested lymph nodes was higher in the laparoscopic approach (median 32 versus 28, p < 0.0001), and the proportion of positive resection margins was higher (p = 0.021) in the open group (5.9%) than in the laparoscopic group (3.2%). There was no significant difference between the groups in five-year overall survival rates (77.4% laparoscopic versus 75.2% open, p = 0.229). CONCLUSION: The adoption of the laparoscopic approach for gastric resection with D2 lymphadenectomy shortened the length of hospital stay and reduced postoperative complications with respect to the open approach. The five-year overall survival rate after laparoscopy was comparable to that for patients who underwent open D2 resection. The types of surgical approaches are not independent predictive factors for five-year overall survival.

15.
Int J Med Robot ; 17(4): e2259, 2021 Aug.
Article in English | MEDLINE | ID: mdl-33825351

ABSTRACT

BACKGROUND: Pancreaticoduodenectomy (PD) is one of the most demanding interventions for digestive surgeons. R0 resection is a key point for the overall survival and disease-free survival. Total mesopancreas excision (TMpE) has been described by laparotomy but laparoscopy did not provide good results probably because of the technical difficulties of the approach. We propose a standardised total robotic approach. METHODS: In this step-by-step technical description, we propose as example, a case of a 53-year-old man with a pancreatic head adenocarcinoma with doubts about the invasion of the mesopancreas surrounding superior mesenteric artery. The mesopancreas hanging manoeuver allows us to perform a TMpE. RESULTS: The surgery performed was a robotic artery first pancreaticoduodenectomy with TMpE. The pathological result was pancreatic ductal adenocarcinoma pT2, N1 (1/23), M0, V0, L0, Pn0, R0. CONCLUSIONS: Robotic approach is safe, effective and reproductible. Through a standardised technique, it may overcome some of the technical difficulties of laparoscopic PD.


Subject(s)
Laparoscopy , Pancreatic Neoplasms , Robotic Surgical Procedures , Humans , Male , Middle Aged , Pancreas/surgery , Pancreatectomy , Pancreatic Neoplasms/surgery , Pancreaticoduodenectomy
17.
Chirurgia (Bucur) ; 115(1): 80-88, 2020.
Article in English | MEDLINE | ID: mdl-32155402

ABSTRACT

Adrenalectomy is nowadays a procedure routinely performed by minimally invasive surgery. In this article we aim to describe in depth our technique for laparoscopic and robotic left and right adrenalectomies, by using four cases and discussing the advantages and disadvantages of each technique.


Subject(s)
Adrenal Gland Neoplasms/surgery , Adrenalectomy/methods , Laparoscopy/methods , Robotic Surgical Procedures/methods , Adrenal Gland Neoplasms/pathology , Female , Humans , Male , Middle Aged , Minimally Invasive Surgical Procedures/methods , Treatment Outcome
19.
Surg Radiol Anat ; 41(3): 343-345, 2019 Mar.
Article in English | MEDLINE | ID: mdl-30547210

ABSTRACT

PURPOSE: Our aim is to present a rare case of anatomic variation of the arterial blood supply to the liver because preoperative knowledge of hepatic vascular variations is mandatory in hepatic surgery and liver transplantation. METHODS: We present a case of unusual arterial blood supply to the liver, a right hepatic artery coming from the splenic artery, associated to a classical common hepatic artery and a left hepatic artery from the left gastric artery. Preoperative diagnosis was made using CT-scan and 3D reconstruction. RESULTS: The right hepatic artery was found behind the portal vein and its diameter showed its importance in the vascularisation of the liver. To our knowledge this type of variation has only twice been described before. The accuracy of the 3D reconstruction allowed us to adopt the best surgical strategy to avoid lesions of the two accessory arteries which proved important sources of blood supply. CONCLUSIONS: Precise preoperative evaluation of liver blood supply has great importance on surgical, transplantation strategy and outcome and rare anatomic variations have to be known to avoid lesions of potentially important arteries. New techniques of 3D reconstruction can ease the preoperative recognition of such difficult anatomic variations.


Subject(s)
Gastric Artery/anatomy & histology , Hepatic Artery/anatomy & histology , Splenic Artery/anatomy & histology , Anatomic Variation , Cadaver , Dissection , Humans , Imaging, Three-Dimensional , Tomography, X-Ray Computed
20.
Cir. Esp. (Ed. impr.) ; 96(10): 634-639, dic. 2018. tab, ilus
Article in Spanish | IBECS | ID: ibc-176531

ABSTRACT

INTRODUCCIÓN: La gastrectomía total es una cirugía con importante morbimortalidad perioperatoria que es considerada el tratamiento de elección en el cáncer gástrico proximal. Descrita por primera vez en 1980, nuestro grupo describió y estandarizó la gastrectomía 95% totalmente laparoscópica en 2014. Esta técnica pretende disminuir las complicaciones de la gastrectomía total sin descuidar la radicalidad oncológica de la misma. Se presentan los primeros resultados de una cohorte de casos consecutivos tras 4 años realizando la técnica en 2 centros hospitalarios. MÉTODOS: Se ha llevado a cabo un estudio prospectivo observacional en 67 pacientes con gastrectomía 95% laparoscópica realizadas entre 2014 y 2017. El objetivo principal ha sido la detección de complicaciones (Clavien Dindo > IIIa), centrándose en la fuga anastomótica como la más importante. Objetivo secundario fue valorar la calidad de la cirugía oncológica. RESULTADOS: Se incluyeron 67 pacientes consecutivos en los que se realizó gastrectomía 95% totalmente laparoscópica. No existió ningún caso de fuga anastomótica, 2 pacientes (2,98%) presentaron una o más complicaciones Clavien Dindo ≥ IIIa. La estancia total fue de 6 (3-13) días. Se realizó resección radical R0 en todos los pacientes. CONCLUSIONES: La gastrectomía 95% permite en pacientes seleccionados cumplir los estándares oncológicos de resección en el cáncer gástrico proximal de manera reproductible y segura, disminuyendo los riesgos perioperatorios como la fuga anastomótica. Se trata de un estudio prospectivo observacional no comparativo, por lo que son necesarios más estudios para valorar la estandarización de la técnica


INTRODUCTION: Total gastrectomy is a surgery with significant perioperative morbidity and mortality, being considered the treatment of choice in proximal gastric cancer. First described in 1980, our group reported and standardized totally laparoscopic 95% gastrectomy in 2014. This technique aims to reduce the complications of total gastrectomy while maintaining oncological radicality. We present the initial results from a cohort of consecutive cases after performing the technique for 4 years at 2 hospital centers. METHODS: A prospective observational study was carried out in 67 patients with laparoscopic 95% gastrectomy between 2014 and 2017. The main objective has been to detect complications (Clavien Dindo> IIIa), focusing on anastomotic leaks as the most important. The secondary objective was to assess the quality of oncological surgery. RESULTS: Sixty-seven consecutive patients were included, in whom 95% totally laparoscopic gastrectomy was performed. There was no case of anastomotic leak. Two patients (2.98%) had one or more Clavien Dindo complications equal to or greater than IIIa. The total hospital stay was 6 (3-13) days. R0 radical resection was performed in all patients. CONCLUSIONS: 95% gastrectomy allows selected patients to meet the oncological standards of resection in proximal gastric cancer in a reproducible and safe manner, reducing perioperative risks such as anastomotic leakage. It is a non-comparative observational prospective study, so more studies are needed to assess the standardization of the technique


Subject(s)
Humans , Male , Female , Adult , Middle Aged , Aged , Aged, 80 and over , Gastrectomy/methods , Gastrectomy/adverse effects , Anastomotic Leak/diagnosis , Endoscopy , Prospective Studies , Observational Study , Anastomotic Leak/surgery , Stomach Neoplasms/therapy , Neoadjuvant Therapy/methods
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