ABSTRACT
Bacille Calmete-Guerin vaccine is widely administered to reduce the risk of severe tuberculosis disease in children. Recent global vaccine supply issues have led to the use of alternative products, which may vary in side effect profile. We report on the safety of the Polish (Moreau strain) "Bacille Calmete-Guerin-10" vaccine in an Australian cohort. Using active surveillance, we identified an adverse event rate of 54.6 per 10,000 doses (95% confidence interval: 38.5-75.2), which was comparable to that reported with the Danish Sanofi-Pasteur and Connaught strains.
Subject(s)
BCG Vaccine/adverse effects , BCG Vaccine/supply & distribution , Mycobacterium bovis/classification , Tuberculosis/prevention & control , Vaccination/adverse effects , Australia , BCG Vaccine/administration & dosage , BCG Vaccine/classification , Child, Preschool , Cohort Studies , Humans , Infant , Mycobacterium bovis/immunology , Risk FactorsABSTRACT
We describe 2 preterm neonates with transient hepatitis B surface (HBs) antigenemia detected after Hepatitis B vaccination. Repeat serology in both cases tested negative for hepatitis B surface antigen, confirming transient HBs antigenemia. The duration of transient HBs antigenemia affirms current literature in the pediatric population.
