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6.
Farmakol Toksikol ; 39(4): 436-40, 1976.
Article in Russian | MEDLINE | ID: mdl-1027569

ABSTRACT

The effect of prostaglandin E1 in a concentration of 0.1 gamma/ml on the aggregation and disaggregation of thrombocytes and erythrocytes in vitro was studied. Prostaglandin E1 was found to materially reduce the aggregation and to produce disaggregation of thrombocytes. A somewhat diminished aggregation of erythrocytes was also noted. Prostaglandin E1 failed to cause disaggregation of erythrocytes.


Subject(s)
Erythrocyte Aggregation/drug effects , Platelet Aggregation/drug effects , Prostaglandins E/pharmacology , Adenosine Diphosphate/antagonists & inhibitors , Adenosine Diphosphate/pharmacology , Animals , Drug Antagonism , Female , In Vitro Techniques , Male , Rabbits
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