ABSTRACT
Cellulose and its forms are widely used in biomedical applications due to their biocompatibility, biodegradability and lack of cytotoxicity. It provides ample opportunities for the functionalization of supported magnetic nanohybrids (CSMNs). Because of the abundance of surface hydroxyl groups, they are surface tunable in either homogeneous or heterogeneous solvents and thus act as a substrate or template for the CSMNs' development. The present review emphasizes on the synthesis of various CSMNs, their physicomagnetic properties, and potential applications such as stimuli-responsive drug delivery systems, MRI, enzyme encapsulation, nucleic acid extraction, wound healing and tissue engineering. The impact of CSMNs on cytotoxicity, magnetic hyperthermia, and folate-conjugates is highlighted in particular, based on their structures, cell viability, and stability. Finally, the review also discussed the challenges and prospects of CSMNs' development. This review is expected to provide CSMNs' development roadmap in the context of 21st-century demands for biomedical therapeutics.
Subject(s)
Cellulose/chemistry , Magnetite Nanoparticles/chemistry , Animals , Drug Carriers/chemistry , Enzymes, Immobilized/chemistry , Humans , Magnetic Phenomena , Magnetic Resonance Imaging , Nucleic Acids/isolation & purification , Smart Materials/chemistry , Solid Phase Extraction/methods , Tissue Engineering/methods , Tissue Scaffolds/chemistry , Wound HealingABSTRACT
This work demonstrates a broadband polarization filter based on copper-filled photonic crystal fiber (CFPCF). The proposed fiber is fabricated using the conventional stack-and-draw method. The polarization filter properties of the proposed CFPCF are investigated numerically by considering the cross-sectional scanning electron microscopy image of the fabricated CFPCF. It is observed that the magnitude of cross talk reached up to -206 dB over 0.8 mm length with a broad bandwidth of 282 nm at a central wavelength of 1790 nm. In addition, the polarization characteristics of the CFPCF including cross talk, central wavelength, and bandwidth can be adjusted by varying the diameter of the copper wire. It is shown that the resonance wavelength of the proposed filter can be tuned over the wide range of wavelengths from 1390 to 1890 nm. We have shown that by adjusting the copper wire diameter to 0.32Λ and 0.48Λ µm (Λ is pitch size), the proposed filter can operate at communication bands of 1310 and 1550 nm, respectively. The results suggest high-potential of the proposed fiber for polarization filtering and other sensing applications.
