ABSTRACT
Results of 45 cluster sample surveys to evaluate the immunization coverage in Iran during 1986 is reported. Overall, 55% of children between the ages of 12-23 months have complete immunization. Apart from mothers' knowledge and motivations, residence in the rural areas and utilization of antenatal care show positive association with immunization coverage. On the other hand, maternal tetanus immunization, hospital delivery and education of birth attendants for deliveries outside hospital, and the sex of the child do not seem to be associated with the child's immunization status. These and other results are discussed.
Subject(s)
Health Knowledge, Attitudes, Practice , Immunization , Mothers/psychology , Preventive Health Services , Female , Humans , Infant , Iran , Male , Patient Compliance , Risk Factors , Rural PopulationABSTRACT
During the period 1986-1988, the expression of anti-HDV in different high-risk groups and its clinical impact on patients with HBV-related chronic liver disease and hepatocellular carcinoma was investigated in Iran. Using the ELISA technique, we observed a 2.5% anti-HDV positivity in asymptomatic chronic HBsAg carriers (3 of 120); in hemophiliacs, two of six HBsAg carriers were positive for anti-HDV and zero of 50 anti-HBs positives. Anti-HBs positive dialysis patients were positive for anti-HDV in 2.0% of the cases (1 of 50), whereas the rate of anti-HDV positivity was 44.5% in hemodialysis patients positive for HBsAg (16 of 36). The figures were comparable in HBsAg positive patients with chronic active hepatitis and cirrhosis (49.2%; 31 of 63). Moreover, anti-HDV was detected in five of eight patients with hepatocellular carcinoma. These data indicate the endemicity of delta infection in Iran. The increased incidence among hepatocellular carcinoma patients is an interesting finding to be further investigated with larger groups of patients in this region.
Subject(s)
Carcinoma, Hepatocellular/epidemiology , Hepatitis D/epidemiology , Liver Neoplasms/epidemiology , Adolescent , Adult , Carcinoma, Hepatocellular/etiology , Chronic Disease , Hepatitis Antibodies/analysis , Hepatitis B/complications , Hepatitis B Surface Antigens/analysis , Hepatitis B e Antigens/analysis , Hepatitis B e Antigens/immunology , Hepatitis D/complications , Hepatitis Delta Virus/immunology , Humans , Iran/epidemiology , Liver Diseases/epidemiology , Liver Neoplasms/etiology , Male , Middle Aged , Prevalence , Risk FactorsABSTRACT
The results are presented of a case-control study conducted in the north of Iran. The main aim was to study factors identified in a previous study as potentially causally related to cancer of the oesophagus. Other tumours (lung, stomach, breast, large bowel, larynx and pharynx) were included to distinguish findings specific for oesophageal cancer from general characteristics of cancer patients, due for example to ascertainment bias, and to verify that expected associations, such as between lung cancer and cigarette smoking, would emerge under the prevailing field conditions. Two controls were chosen per case, matched for village of residence, age, sex and language group, Reinterviewing was performed to a limited extent to assess the accuracy of replies to questionnaires. The following were found not to be associated with oesophageal cancer: consumption of sheep's milk and yoghurt, sesame oil, chewing of nass, making of carpets, use of pregnancy diets, salting and sun-drying of meat and use of wild spinach. The use of opium, bread and tea could not be assessed in the retrospective framework. Strongly associated with risk of oesophageal cancer were low socio-economic status and low intake of fresh fruit and vegetables. The two factors each had an independent effect, and were more marked for oesophageal cancer than for the other tumours.
