ABSTRACT
Reports of an association between epilepsy and coeliac disease (CD) are not new. Chapmann reported a prevalence of epilepsy in CD of 5.5% and accepted a figure of 0.5% for the community. Prevalence of coeliac disease among epileptic patients is not well established. The aim of this study is to determine the prevalence of CD in epileptic patients for this 49 epileptic patients (31 male and 28 female) were selected between January 96 et June 99 to underwent fibroscopy with intestinal biopsy. Anti body to gluten were measured in most patients. The patients with villous atrophy underwent cranial computed tomography. 4 of 49 patients (8.1%) were identified as having coeliac disease on the basis of a flat intestinal mucosa with increasing of LIE. 2 among this 4 patients had recurrent diarrhea. Any patient showed cerebral calcification associated with epilepsy and CD. Only one patient among 4, followed a gluten free-diet with a significant reduction in seizure frequency. This suggest that CD should be ruled out in all case of epilepsy of unexplained origin.
Subject(s)
Celiac Disease/complications , Epilepsy/complications , Intestinal Mucosa/pathology , Microvilli/pathology , Adolescent , Adult , Aged , Autoantibodies/blood , Female , Glutens/administration & dosage , Humans , Male , Middle AgedABSTRACT
Pancreatic involvement in sarcoïdosis is exceptional. We report a case of pancreatic sarcoïdosis diagnosed during the etiologic work-up done for a pancreatic mass associated to a polyadenopathy. Under corticotherapy evolution is favorable with regression of the pancreatic lesions.
Subject(s)
Pancreatic Diseases/pathology , Sarcoidosis/pathology , Adrenal Cortex Hormones/therapeutic use , Aged , Female , Humans , Pancreatic Diseases/drug therapy , Sarcoidosis/drug therapyABSTRACT
Pulmonary arterial hypertension PAH is one of the rare expressions of cirrhosis and defined by a pressure more than 30 mmHg. We report our results in a Tunisian Seria results: 21 cirrhotic patients (19M/12F) with a median age of 60 years (22 to 85) explored by cardiac echographic with measures of PAH. We observe an elevated PAH in 31% of cases. Conclusion elevated PAH is relatively frequent during the evolution of cirrhosis. This symptom needs to be systematically explored in patients proposed for liver graft because increased PAH is a contraindication for liver transplantation.
