[Amyloid goiter]. / Az amyloid golyváról.

Amyloid goitre is at an extremely rare occurrence. Authors review the origin of disease and its symptoms, diagnostic and therapeutic tools. The disease may be due to either primary or secondary systemic or local amyloidosis. Diagnosis may be made even before surgery on anamnestic data, on very rapid growth of thyroid glands, on diffuse appearance, on other symptoms of systemic amyloidosis, on findings of iconographic procedures and on detection of amyloid in aspirates. Final diagnosis is based on histology. Surgical therapy is aiming at avoidance of the existing and the threatening consequences of expanding mass. The outcome is independent from thyroid surgery, it is related to other manifestations of amyloidosis. Concerning with the present case the chronic superior vena cava syndrome and chylous pleural effusion as first described symptoms and asymptomatic hyperthyroxinaemia is emphasised. Neither other organ involvement, nor primary amyloidogenous molecula was found during the 18 months follow up, so patient has secondary and localised amyloidosis.

Clinico-bacteriological examination of Betadine skin disinfectant fluid and liquid soap in hospitalized patients and hospital employees.

The effectivity of Betadine skin and mucosa disinfectant solution and Betadine hand disinfectant soap (MUNDIPHARMA A. G. and EGIS Pharmaceuticals has been examined in hospitalized patients and hospital employees. The history of the production of polyvynilpyrrolidone-iodine (PVP-Iodine) the mechanism of actions and the biological effects of these products have been discussed. Bacteriological samples were collected from the skin of four regions most frequently used for injection (fossa cubitalis, right and left hands and gluteal region, right and left sides) of 10 hospitalized patients before and after washing these regions with Betadine. The average of 68 microorganisms Colony Forming Unit (CFU) recorded before disinfection decreased below 1 CFU on average in the samples taken after disinfection. From both hands of 6 hospital employees 190 CFUs could be demonstrated following washing hands with the commonly used soap. After washing hands with Betadine soap a total of 1 CFU could be demonstrated. The hands of 44 hospital employees were infected with E. coli of non-pathogenous reference strain whereafter samples were collected. After the disinfection of the hands with Betadine liquid soap samples were taken again. In the samples taken before disinfection an average of 745 CFUs, in samples taken after disinfection an average total of 11 CFUs were found. The results prove the outstanding disinfectant action of the two examined Betadine products.