ABSTRACT
Mycoplasma hominis is a common colonizer of the lower genitourinary tract. Although its clinical relevance for causing urogenital infections in immunocompetent individuals is controversial, this bacterium has been involved in severe invasive infections in allograft recipients. In this report, we describe two cases of M. hominis infection in two young renal transplant recipients within the first month post-transplant. Although at first no epidemiological link between the two cases had been suspected, whole-genome sequencing (WGS) analysis showed that both isolates were identical, highly suggestive of an origin with the common organ donor.
Subject(s)
Kidney Transplantation/adverse effects , Mycoplasma Infections/microbiology , Mycoplasma hominis/genetics , Transplant Recipients , Whole Genome Sequencing , Adult , Anti-Bacterial Agents/therapeutic use , Ethylene Glycols/poisoning , Humans , Male , Nephritis, Interstitial/complications , Renal Insufficiency/etiology , Renal Insufficiency/surgery , Tissue Donors , Young AdultABSTRACT
A 46-year-old immunosuppressed patient presented with a breast implant-associated infection 10 years after breast augmentation in Southeast Asia. No pathogen was identified in the initial conventional microbiological workup. Subsequently, infection with Mycobacterium abscessus-a nontuberculous mycobacteria-was diagnosed using a special culture technique. Increased rates of such infections are reported after cosmetic surgery in foreign countries, presumably due to inoculation with these ubiquitous pathogens. This case highlights the fact that the differential diagnosis and thus the microbiological workup should be extended in cases without initial pathogen detection.
Subject(s)
Breast Implants/adverse effects , Foreign Bodies/microbiology , Mastodynia/etiology , Mycobacterium Infections, Nontuberculous/diagnosis , Nontuberculous Mycobacteria/isolation & purification , Prosthesis-Related Infections/microbiology , Surgical Wound Infection/microbiology , Breast Implants/microbiology , Fever/etiology , Humans , Immunocompromised Host , Middle Aged , Mycobacterium Infections, Nontuberculous/microbiologyABSTRACT
A patient with acute myeloid leukemia developed disseminated tuberculosis with cerebral involvement in the early phase of induction chemotherapy before allogenic stem cell transplantation. He presented with persisting fever of unknown origin, and initially misinterpreted organ lesions in CT scans.
