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Eur Urol ; 18(4): 299-301, 1990.
Article in English | MEDLINE | ID: mdl-2127019

ABSTRACT

Changes in testicular morphology are quantified in patients with metastatic prostatic cancer, treated with LHRH agonist Buserelin and compared with testes of young transsexuals and patients with metastatic prostatic cancer treated with orchidectomy only. No significant changes within 18 months were seen, suggesting reversibility of LHRH agonist effects on testicular morphology in this time period. Histomorphometrics of the testis are useful to quantify these changes.


Subject(s)
Buserelin/adverse effects , Prostatic Neoplasms/drug therapy , Testis/drug effects , Adult , Aged , Aged, 80 and over , Buserelin/therapeutic use , Humans , Leydig Cells/drug effects , Male , Middle Aged , Spermatogenesis/drug effects , Testis/pathology
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