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2.
Pathol Int ; 66(11): 633-639, 2016 Nov.
Article in English | MEDLINE | ID: mdl-27671838

ABSTRACT

Ciliated muconodular papillary tumor (CMPT) of the lung is a newly defined and extremely rare tumor characterized by a papillary growth pattern, consisting of ciliated columnar cells, mucous cells, and basal cells with abundant mucin production. Tumor definitions and clinicopathological features continue to be debated. Herein, we report five surgical cases of CMPT to characterize its radiographic, gross, and microscopic features. The five cases involved three male patients aged 80, 67, and 66 years, and two female patients aged 73 and 70 years. Three cases were discovered during health care screenings, and two cases were found during follow-up for another synchronous cancer. Histopathological examination revealed that the tumor tissue was composed of ciliated columnar cells, mucous cells, and basal cells with abundant mucin production. Neither nuclear atypia nor mitotic figures were observed. All patients had good prognoses. The benign histological features and clinical courses in these five cases suggest that CMPT is an independent and benign tumor of the lung.


Subject(s)
Carcinoma, Papillary/pathology , Lung Neoplasms/pathology , Aged , Aged, 80 and over , Carcinoma, Papillary/diagnosis , Epithelial Cells/pathology , Female , Goblet Cells/pathology , Humans , Lung Neoplasms/diagnosis , Male , Mucins/metabolism
3.
Nihon Shokakibyo Gakkai Zasshi ; 108(3): 470-7, 2011 Mar.
Article in Japanese | MEDLINE | ID: mdl-21389670

ABSTRACT

A 72-year-old man was admitted to our hospital for further investigation of pancreatic mass. Ultrasonography revealed hypoechoic mass with hyperechoic and aechoic area. Contrast enhanced ultrasonography (CE-US) revealed a vascular image in the lesion. CT showed some enhanced parts of low density mass in the pancreatic body, which was recognized as low-, high- and relatively high-intensity mass on T1-, T2-WI MRI and MRCP, respectively. The final pathological diagnosis showed mucinous carcinoma. CE-US may be useful for diagnosis of mucinous carcinoma.


Subject(s)
Adenocarcinoma, Mucinous/diagnostic imaging , Pancreatic Neoplasms/diagnostic imaging , Aged , Humans , Image Enhancement , Male , Ultrasonography/methods
4.
Gastrointest Endosc ; 57(6): 691-4, 2003 May.
Article in English | MEDLINE | ID: mdl-12709699

ABSTRACT

BACKGROUND: The most common major complication of colonoscopic polypectomy is postpolypectomy hemorrhage. Although several factors have been implicated in the occurrence of hemorrhage, accurate prediction of delayed bleeding remains difficult. This randomized controlled trial evaluated the efficacy of prophylactic clip application for prevention of delayed postpolypectomy bleeding. METHODS: Postpolypectomy ulcers created by colonoscopic removal of polyps (mean size 7.8 [4.0] mm) with the endoscopic mucosal resection technique were randomly assigned to prophylactic clip placement (n = 205) or no clip (n = 208). Baseline characteristics of the patients and polyps excised were comparable between the groups. Delayed bleeding was defined as the postprocedure passage of bloody stool or massive hematochezia. The site of delayed bleeding was identified at emergent colonoscopy. RESULTS: Delayed bleeding was identified from 2 ulcers in each group from 1 to 4 days after resection (mean 2.3 days). Delayed bleeding occurred from 0.98% of ulcers in the clip group and 0.96% in the non-clip group (p > 0.9999). No patient with delayed bleeding required transfusion or surgery. CONCLUSIONS: Prophylactic clip placement did not decrease the occurrence of delayed bleeding after colonoscopic polypectomy.


Subject(s)
Colonic Polyps/surgery , Colonoscopy/adverse effects , Gastrointestinal Hemorrhage/prevention & control , Hemostasis, Surgical , Adenocarcinoma/surgery , Adenoma, Villous/surgery , Adult , Aged , Aged, 80 and over , Female , Gastrointestinal Hemorrhage/etiology , Hemostasis, Surgical/instrumentation , Humans , Male , Middle Aged , Prospective Studies
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