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Intern Med ; 59(24): 3177-3181, 2020 Dec 15.
Article in English | MEDLINE | ID: mdl-32788545

ABSTRACT

Although cardiovascular involvement is a well-known complication correlated with a poor prognosis in patients with systemic sclerosis, there are few reports on valvular heart disease. Forty patients with systemic sclerosis were retrospectively analyzed. Valvular heart disease was found in six patients, five of whom had severe tri-leaflet aortic stenosis. Three of these 5 patients were ≤71 years old. Two frail elderly patients who underwent transcatheter aortic valve replacement died within two years. Premature-onset aortic stenosis is not uncommon in patients with systemic sclerosis. When considering mechanical intervention, the evaluation of frailty is important.


Subject(s)
Aortic Valve Stenosis , Scleroderma, Systemic , Transcatheter Aortic Valve Replacement , Aged , Aortic Valve/surgery , Aortic Valve Stenosis/diagnostic imaging , Aortic Valve Stenosis/surgery , Frail Elderly , Humans , Retrospective Studies , Risk Factors , Scleroderma, Systemic/complications , Transcatheter Aortic Valve Replacement/adverse effects , Treatment Outcome
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