[Controlling effect of T lymphocyte suppressors on the proliferation of cells in various tissues]. / Kontroliruiushchee vliianie T-limfotsitov-supressorov na proliferatsiiu kletok v razlichnykh tkaniiakh.

The changes in mitotic index of mouse bone marrow, spleen, liver, kidneys, small intestine, cornea were studied during alterations in the number of T-suppressors. It was found that mitotic activity in all tissues investigated enhanced significantly after a decrease in the number of T-suppressors caused by single injection of an antiserum against T-suppressors. On the contrary, the mitotic index diminished significantly after the transfer of tolerant spleen lymphoid cell suspension enriched by T-suppressors to normal syngeneic mice. These data indicate that T-suppressors are responsible for the control over cell proliferation in nonlymphoid tissues.