ABSTRACT
Long-term studies of spread of rhabdoviruses which indicated their harmfulness in different plant species under conditions of environmental factors were first discussed. Their harmfulness to different plant species under environmental conditions was shown. A comparative description of rhabdoviruses with similar pathogens of the mushrooms is carried out. Thus the main focus was on the morphology and structure of the pathogens. These data are extremely important in the study of distribution of the rhabdovirus on crops in different regions.
Subject(s)
Agaricales/virology , Edible Grain/virology , Plant Diseases/virology , Rhabdoviridae/ultrastructure , Animals , Carps/virology , Fish Diseases/virology , Host Specificity , Rhabdoviridae/pathogenicity , Species SpecificityABSTRACT
The influence of probiotic strains of Lactobacillus casei IMV B-7280, Lactobacillus acidophilus IMV B-7279, Bifidobacterium animalis VKL, Lactobacillus delbrueckii subsp. bulgaricus IMV B-7281 and Bifidobacterium animalis VKB, each strain separately, to the range of the urogenital tract microflora in physiological norm and in cases of experimental intravaginal staphylococcosis of mice induced by Staphylococcus aureus 8325-4. It was found that all these strains had different efficiency in Staphylococcus aureus 8325-4 growth suppression in the vagina of infected mice and affect the spectrum of microorganisms. Lactobacillus casei IMV B-7280 strain had effective antistaphylococcal effect and reduced the number of coliform bacteria and fungi in the vagina in cases of intravaginal staphylococcosis of mice. Lactobacillus casei IMV B-7280 strain is promising to create probiotic drugs effective in treating intravaginal staphylococcosis.
Subject(s)
Probiotics/therapeutic use , Staphylococcal Infections/drug therapy , Vagina/microbiology , Vaginosis, Bacterial/drug therapy , Administration, Intravaginal , Animals , Antibiosis , Colony Count, Microbial , Disease Models, Animal , Female , Mice , Mice, Inbred BALB C , Probiotics/administration & dosage , Probiotics/pharmacology , Staphylococcal Infections/microbiology , Vagina/drug effects , Vaginosis, Bacterial/microbiologyABSTRACT
The results of research on changes in the level of apoptosis among the spleen cells during the development of intravaginal staphylococcal infection in experimental models of different genetic mice lines are given in the paper. Intravaginal injection of Staphylococcus aureus resulted in an increased number of cells with morphological characteristics of apoptosis in underbred and line BALB/c mice, while it decreased in the ICR line mice. The level of the apoptotic cells in the underbred and line BALB/c mice was accompanied by some level of microorganisms that were seeded out of kidneys--the higher was the number of microorganisms, the more apoptotic cells were indicated.
