[Lipid peroxidation in patients with hypertension and renal hypertension against a background of diabetes mellitus]. / Perekisnoe okislenie lipidov u bol'nykh gipertonicheskoi bolezn'iu i pochechnoi gipertenziei na fone sakharnogo diabeta.

Time course of changes was studied in parameters characterizing lipid peroxidation (LPO) and the total lipids counts in red cell membranes (RCM) and blood plasma (BP) of patients with hypertensive disease (HD) and arterial hypertension in chronic pyelonephritis against the background of diabetes mellitus (DM). The study groups were DM patients (group I), those with coexistent HDDM (group II), and those with arterial hypertension caused by chronic pyelonephritis in the presence of DM (group III). All three groups of patients demonstrated intensification of the cellular membrane- and blood plasma LPO as well as increase in the total lipids counts. HDDM results in much higher levels of the RCM and BP LPO products. Relatively higher RCM and BP LPO in group II patients as compared with III one, permits differentiating the above pathologic mixes. The results obtained allow us to recommend that antioxidants be incorporated into a complex therapy to be adopted for treating the above conditions.

[Eosinophilic reactions in bronchial asthma patients and the possibilities to neutralize them under sanatorium treatment]. / Eozinofil'nye reaktsii u bol'nykh bronkhial'noi astmoi i vozmozhnosti ikh neitralizatsii v usloviiakh sanatornogo lecheniia.

Patients with eosinophilic variant of bronchial asthma demonstrate high levels of fibrinolytic activity in their bronchial secretion along with low content in same of Ig A, as evidenced by findings obtained in the course of sanatorium treatment. There is usually no correlation between the above changes and routine methods of health resort treatment. The judicious employment in a complex of therapeutic measures of aerosols of hydrocarbonate of sodium and heparin promotes neutralization of cationic proteins and large major protein of eosinophiles in the bronchial lumen whereby there occurs normalization of Ig A levels in the sputum along with lowering of its fibrinolytic activity.

[A comparative evaluation of the efficacy of immunocorrection in children with bronchial asthma living in ecologically contrasted regions]. / Sravnitel'naia otsenka éffektivnosti immunokorrektsii u detei, bol'nykh bronkhial'noi astmoi, prozhivaiushchikh v ékologicheski kontrastnykh regionakh.

Overall 50 children suffering from infectious-allergic bronchial asthma who live in ecologically contrasting regions were examined. Those children residing in unfavourable, in terms of ecological conditions, regions demonstrated diminution of the peripheral blood T-lymphocytes together with a decrease in their functional activity as well as in the activity of interleukin 2. It is in this group of children that immunomodulating effect of thymalin is less apparent. It is suggested that the relevant immune correction in such cases might be achieved through repeated courses of treatment with immunomodulating agents and rehabilitation of patients in favourable ecological conditions together with prescribing of other immunostimulators of selective action in respect of the T-link of the immunity system.

[The structural-functional characteristics of the erythrocyte membrane and the atherosclerotic process]. / Strukturno-funktsional'nye osobennosti membrany éritrotsitov i ateroskleroticheskii protsess.

The content of glycoproteids in erythrocytic membranes and the membrane permeability was studied in 155 patients with atherosclerosis. It is recommended to use values of reduction of the content of glycoproteids in erythrocytic membrane and indices of membrane possibility in the clinical practice with the purpose of a more objective characterization of clinical variants of atherosclerosis, evaluation of the severity of its course and diagnosis of complications.