1.
J Clin Pharm Ther
; 31(2): 193-6, 2006 Apr.
Article
in English
| MEDLINE
| ID: mdl-16635055
ABSTRACT
We report on a woman with borderline personality disorder and a history of childhood trauma that showed significant clinical response with low dosage of topiramate. We propose that topiramate changed some of the main features of this disorder, such as catastrophic reaction to real or imaginary abandonment or rejection, improving adaptive functioning. We hypothesize that topiramate might facilitate memory extinction, therefore decreasing emotional and behavioural reactivity.