ABSTRACT
Chromophobe renal cell carcinoma is an unusual variant of renal carcinoma that has less aggressive behavior than clear cell carcinomas. There are few documented cases of metastases, none of which occurred in the thyroid gland. A case is presented of chromophobe renal cell carcinoma metastatic to the thyroid eight years after right nephrectomy, suspected by FNA-biopsy and confirmed histologically. Although metastases of chromophobe renal cell carcinoma are rare, they may also present in thyroid, even many years after primary tumor diagnosis, just like clear cell carcinomas. Even though the FNA cytology of chromophobe renal cell carcinoma has distinctive features, in the context of the thyroid, it can be mistaken for a primary tumor of that organ. In our case, the history of a previous renal tumor was essential in suggesting a metastatic lesion, and histologic and ultrastructural features allowed its precise identification.
Subject(s)
Carcinoma, Renal Cell/pathology , Carcinoma, Renal Cell/secondary , Kidney Neoplasms/pathology , Thyroid Neoplasms/pathology , Thyroid Neoplasms/secondary , Aged , Biopsy, Needle , Female , HumansABSTRACT
We report a case of a gastric carcinoid tumor in an anemic woman with chronic atrophic gastritis and hypergastrinemia. An antrectomy with excision of a carcinoid tumor was performed; afterwards, gastrinemia was normal. Gastric carcinoids were considered uncommon gastric cancers; however, in recent years they have been studied with increasing interest because, as in chronic atrophic gastritis, it has been suggested that they might be produced by prolonged hypergastrinemia associated with therapeutic use of gastric acid supressors. We discuss the gastrin hypothesis, the different clinical types of gastric carcinoids and its therapeutical management.
Subject(s)
Carcinoid Tumor/complications , Gastrins/blood , Gastritis/etiology , Stomach Neoplasms/complications , Adult , Carcinoid Tumor/blood , Female , Humans , Stomach Neoplasms/bloodABSTRACT
A case of acute non-lymphoblastic leukaemia is reported which appeared as granulocytic sarcoma (GS) with no leukaemic expression in peripheral blood. Aside of the patient's advanced age, the rarity of this entity at the onset of ANLL and the location of the tumour, on the back of the patient's left upper thigh are outstanding features. The difficult diagnosis of such non-leukaemic cases is also stressed here, with regard to the differential diagnosis with non-Hodgkin's lymphoma (NHL). It is concluded that the incidence of GS as a tumour of soft tissues in the extremities is more common in patients over 75 years of age, its frequency being 17-fold that of NHL for the same age and location.
Subject(s)
Leukemia, Myeloid/diagnosis , Soft Tissue Neoplasms/diagnosis , Acute Disease , Aged , Aged, 80 and over , Diagnosis, Differential , Fatal Outcome , Female , Humans , Leukemia, Myeloid/pathology , Lymphoma, Non-Hodgkin/diagnosis , Soft Tissue Neoplasms/pathology , ThighABSTRACT
We report five patients with necrotizing vasculitis with predominant renal involvement; the diagnostic and therapeutics was effected completely at regional hospital. We detach: a) the clinical presentation's forms with rapidly progressive renal failure with microscopic hematuria and minimal proteinuria; b) the biopsy of kidney with necrotizing vasculitis or necrotizing glomerulonephritis (microscopic polyarteritis). We review the necrotizing vasculitis with predominant renal involvement in its pathogenic, clinical and histological aspects, and we insist that the diagnostic and early treatment are fundamental for prognostic's improvement of these patients. We conclude that this diagnostic and treatment can be made in regional hospitals with sensible physicians by the theme.
Subject(s)
Kidney Diseases/classification , Vasculitis/classification , Aged , Female , Glomerulonephritis/classification , Glomerulonephritis/diagnosis , Glomerulonephritis/pathology , Humans , Kidney/pathology , Kidney Diseases/diagnosis , Kidney Diseases/pathology , Male , Middle Aged , Necrosis/classification , Necrosis/diagnosis , Necrosis/pathology , Polyarteritis Nodosa/classification , Polyarteritis Nodosa/diagnosis , Polyarteritis Nodosa/pathology , Vasculitis/diagnosis , Vasculitis/pathologySubject(s)
Amyloidosis/complications , Cholecystitis/etiology , Acute Disease , Aged , Cholecystitis/pathology , Female , Gallbladder/pathology , HumansSubject(s)
Granuloma/complications , Hepatitis/complications , Nephritis, Interstitial/complications , Nephritis/complications , Uveitis, Anterior/complications , Diagnosis, Differential , Female , Granuloma/pathology , Hepatitis/pathology , Humans , Middle Aged , Nephritis/pathology , Nephritis, Interstitial/diagnosis , Nephritis, Interstitial/pathology , Prognosis , Sarcoidosis/diagnosis , Syndrome , Uveitis, Anterior/diagnosisABSTRACT
Two cases of papillary-cystic neoplasm of the pancreas are reported in women aged 22 and 23 years. The patient in the first case presented with acute abdominal pain and hemoperitoneum. This form of presentation has not been previously reported. This type of pancreatic tumor is very rare, exclusively affecting young women, and has a good prognosis despite its various histologic features, which suggest a malignant appearance. The authors consider this neoplasm as having an acinar origin because in the cells of one of the patients we observed ultrastructurally the presence of abundant rough endoplasmatic reticulum with formation of annulate lamellae and a few prezymogen granules.
