1.
Farmaco
; 55(5): 406-9, 2000 May.
Article
in English
| MEDLINE
| ID: mdl-10983288
ABSTRACT
The alpha-beta-unsaturated ketones of 3-arylsydnones (Ia-y) were treated with 1,2-phenylenediamine to obtain the 3-aryl-4-[2'-aryl- 2',4',6',7'-tetrahydro-(1'H)-1',5'-benzodiazepine-4'-yl]sydnones (IIa-y) in high yield. All the new compounds synthesised were screened for antibacterial and antifungal activities.
Subject(s)
Anti-Infective Agents/chemical synthesis , Anti-Infective Agents/pharmacology , Benzodiazepines/chemistry , Sydnones/chemical synthesis , Sydnones/pharmacology , Anti-Bacterial Agents , Anti-Infective Agents/chemistry , Bacteria/drug effects , Fungi/drug effects , Microbial Sensitivity Tests , Sydnones/chemistry , United States
2.
Farmaco
; 55(1): 65-7, 2000 Jan.
Article
in English
| MEDLINE
| ID: mdl-10755234
ABSTRACT
3-Arylsydnones (Ia-u) have been converted into the corresponding 3-aryl-5-methyl-1,3,4-oxadiazolin-2-ones (IIIa-u) by a single-step reaction with bromine in acetic anhydride. In the preliminary screening of all these compounds, the halogen-substituted derivatives have shown antimicrobial activities equal to those of the standard drugs used.
Subject(s)
Anti-Infective Agents/chemical synthesis , Anti-Infective Agents/pharmacology , Oxadiazoles/chemical synthesis , Oxadiazoles/pharmacology , Sydnones/chemistry , Anti-Infective Agents/chemistry , Microbial Sensitivity Tests , Oxadiazoles/chemistry
3.
Arch Pharm (Weinheim)
; 317(1): 59-63, 1984 Jan.
Article
in English
| MEDLINE
| ID: mdl-6703866
4.
Arch Pharm (Weinheim)
; 316(4): 334-9, 1983 Apr.
Article
in English
| MEDLINE
| ID: mdl-6870496
5.
Arch Pharm (Weinheim)
; 314(6): 503-7, 1981 Jun.
Article
in English
| MEDLINE
| ID: mdl-7283680
6.
Arch Pharm (Weinheim)
; 314(5): 470-5, 1981 May.
Article
in English
| MEDLINE
| ID: mdl-7247654
7.
Arch Pharm (Weinheim)
; 313(8): 684-8, 1980 Aug.
Article
in English
| MEDLINE
| ID: mdl-7416926
8.
Arch Pharm (Weinheim)
; 311(2): 109-14, 1978 Feb.
Article
in English
| MEDLINE
| ID: mdl-646585