Improving Understanding of Visual Snow by Quantifying its Appearance and Effect on Vision.

Purpose: Visual snow is the hallmark of the neurological condition visual snow syndrome (VSS) but the characteristics of the visual snow percept remain poorly defined. This study aimed to quantify its appearance, interobserver variability, and effect on measured visual performance and self-reported visual quality. Methods: Twenty-three participants with VSS estimated their visual snow dot size, separation, luminance, and flicker rate by matching to a simulation. To assess whether visual snow masks vision, we compared pattern discrimination thresholds for textures that were similar in spatial scale to visual snow as well as more coarse than visual snow, in participants with VSS, and with and without external noise simulating visual snow in 23 controls. Results: Mean and 95% confidence intervals for visual snow appearance were: size (6.0, 5.8-6.3 arcseconds), separation (2.0, 1.7-2.3 arcmin), luminance (72.4, 58.1-86.8 cd/m2), and flicker rate (25.8, 18.9-32.8 frames per image at 120 hertz [Hz]). Participants with finer dot spacing estimates also reported greater visibility of their visual snow (τb = -0.41, 95% confidence interval [CI] = -0.62 to -0.13, P = 0.01). In controls, adding simulated fine-scale visual snow to textures increased thresholds for fine but not coarse textures (F(1, 22) = 4.98, P = 0.036, ηp2 = 0.19). In VSS, thresholds for fine and coarse textures were similar (t(22) = 0.54, P = 0.60), suggesting that inherent visual snow does not act like external noise in controls. Conclusions: Our quantitative estimates of visual snow constrain its likely neural origins, may aid differential diagnosis, and inform future investigations of how it affects vision. Methods to quantify visual snow are needed for evaluation of potential treatments.

Selectivity for local orientation information in visual mirror symmetry perception.

Mirror symmetry is a global percept formed from specific arrangements of matching local information. It has been shown that some features of this local information can interact with the global percept, interfering with symmetry perception. One such feature is orientation; it is well established that the orientation of the symmetry axis has a significant impact on symmetry perception, but the role of local orientation of individual elements is still equivocal. Some studies have argued for no role of local orientation in symmetry perception, while other studies have shown a detrimental effect of certain local orientation combinations. Using dynamic stimuli composed of oriented Gabor elements with increasing temporal delay (SOA) between the onset of the first and second element in a symmetric pair, we systematically map how orientation variation within and between symmetric pairs affected the temporal integration of symmetric patterns in five observers. This method allows consideration of both sensitivity to symmetry (threshold, or T0) as well as the duration of visible persistence of each condition through the visual system (P). Our results show a clear role for local orientation in symmetry perception and highlight the importance of local orientation in symmetry perception. Our findings reinforce the need for more nuanced perceptual models incorporating local element orientation, which is currently unaccounted for.

Contribution of higher-order structure to perception of mirror symmetry: Role of shapes and corners.

Visual mirror symmetry is a global feature that is dependent on specific low-level relationships between component elements. Initially conceptualized as virtual lines between paired elements, it has been suggested that higher-order structure between pairs of symmetric elements forming virtual four cornered shapes may also be important for strengthening the percept of mirror symmetry. We utilize corner elements, formed by joining two Gabor elements along a central midline creating vertices with variable internal angles, in a temporal integration paradigm. This allows us to specifically manipulate the presence and type of higher-order versus lower-order structure in patterns with symmetrically placed elements. We show a significant contribution of higher-order structure to the salience of visual symmetries compared with patterns with only lower-order structures. We also find that although we are more sensitive to patterns with higher-order structure, there is no difference in the temporal processing of higher-order versus lower-order patterns. These findings have important implications for existing spatial filter models of symmetry perception that rely on lower-order structures alone and reinforces the need for elaborated models that can more readily capture the complexities of real-world symmetries.

Target motion misjudgments reflect a misperception of the background; revealed using continuous psychophysics.

Determining the velocities of target objects as we navigate complex environments is made more difficult by the fact that our own motion adds systematic motion signals to the visual scene. The flow-parsing hypothesis asserts that the background motion is subtracted from visual scenes in such cases as a way for the visual system to determine target motions relative to the scene. Here, we address the question of why backgrounds are only partially subtracted in lab settings. At the same time, we probe a much-neglected aspect of scene perception in flow-parsing studies, that is, the perception of the background itself. Here, we present results from three experienced psychophysical participants and one inexperienced participant who took part in three continuous psychophysics experiments. We show that, when the background optic flow pattern is composed of local elements whose motions are congruent with the global optic flow pattern, the incompleteness of the background subtraction can be entirely accounted for by a misperception of the background. When the local velocities comprising the background are randomly dispersed around the average global velocity, an additional factor is needed to explain the subtraction incompleteness. We show that a model where background perception is a result of the brain attempting to infer scene motion due to self-motion can account for these results.

Continuous psychophysics for two-variable experiments; A new "Bayesian participant" approach.

Interest in continuous psychophysical approaches as a means of collecting data quickly under natural conditions is growing. Such approaches require stimuli to be changed randomly on a continuous basis so that participants can not guess future stimulus states. Participants are generally tasked with responding continuously using a continuum of response options. These features introduce variability in the data that is not present in traditional trial-based experiments. Given the unique weaknesses and strengths of continuous psychophysical approaches, we propose that they are well suited to quickly mapping out relationships between above-threshold stimulus variables such as the perceived direction of a moving target as a function of the direction of the background against which the target is moving. We show that modelling the participant in such a two-variable experiment using a novel "Bayesian Participant" model facilitates the conversion of the noisy continuous data into a less-noisy form that resembles data from an equivalent trial-based experiment. We also show that adaptation can result from longer-than-usual stimulus exposure times during continuous experiments, even to features that the participant is not aware of. Methods for mitigating the effects of adaptation are discussed.

Eliminating brightness induction effects when measuring motion centre-surround suppression of contrast.

The perceived contrast of a central stimulus is supressed when it is embedded in a higher contrast surround, centre-surround suppression of contrast. Local brightness induction effects between the two stimulus regions have been proposed to account for conflicting results when relative grating phases were different. Here, suppression and brightness induction effects are dissociated using a centre-surround arrangement with moving gratings. Four experienced observers were involved in experiments, utilising two-interval forced-choice contrast matching tasks. The stimuli were drifting sinusoidal grating patterns with surrounds (95% contrast) differing in direction of motion and orientation relative to the 40% contrast centre grating. First a 90°-phase-offset same direction surround condition was compared to both same direction (phase aligned) and opposing direction conditions. The reduction in the suppression for the phase-offset condition suggested a reduction in brightness induction influences. Then suppression was examined when surround directions varied and where phase was either fixed or randomised. For small changes in the motion direction between centre and surround (0° to 26.6°) the amount of brightness induction varied sinusoidally with the difference in phase introduced by the direction difference. Finally, the spatial separation between the centre and surround was varied to determine the reduction of suppression and brightness induction with increasing spatial distance. We found both fit an exponential decay function, with surround suppression producing the larger range of influence. Our findings quantify both brightness induction and suppression effects and validate the use of phase randomisation to remove effects of brightness induction when evaluating surround suppression.

The induced motion effect is a high-level visual phenomenon: Psychophysical evidence.

Induced motion is the illusory motion of a target away from the direction of motion of the unattended background. If it is a result of assigning background motion to self-motion and judging target motion relative to the scene as suggested by the flow parsing hypothesis then the effect must be mediated in higher levels of the visual motion pathway where self-motion is assessed. We provide evidence for a high-level mechanism in two broad ways. Firstly, we show that the effect is insensitive to a set of low-level spatial aspects of the scene, namely, the spatial arrangement, the spatial frequency content and the orientation content of the background relative to the target. Secondly, we show that the effect is the same whether the target and background are composed of the same kind of local elements-one-dimensional (1D) or two-dimensional (2D)-or one is composed of one, and the other composed of the other. The latter finding is significant because 1D and 2D local elements are integrated by two different mechanisms so the induced motion effect is likely to be mediated in a visual motion processing area that follows the two separate integration mechanisms. Area medial superior temporal in monkeys and the equivalent in humans is suggested as a viable site. We present a simple flow-parsing-inspired model and demonstrate a good fit to our data and to data from a previous induced motion study.

The Western Australia Olfactory Memory Test: Reliability and Validity in a Sample of Older Adults.

OBJECTIVE: The Western Australia Olfactory Memory Test (WAOMT) is a newly developed test designed to meet a need for a comprehensive measure of olfactory episodic memory (OEM) for clinical and research applications. METHOD: This study aimed to establish the psychometric properties of the WAOMT in a sample of 209 community-dwelling older adults. An independent sample of 27 test-naïve participants were recruited to assess test retest reliability (between 7 and 28 days). Scale psychometric properties were examined using item response theory methods, combined samples (final N = 241). Convergent validity was assessed by comparing performance on the WAOMT with a comprehensive neuropsychological battery of domains (verbal and visual episodic memory, and odor identification), as well as other neuropsychological skills. Based on previous literature, it was predicted that the WAOMT would be positively correlated with conceptually similar cognitive domains. RESULTS: The WAOMT is a psychometrically sound test with adequate reliability properties and demonstrated convergent validity with tests of verbal and episodic memory and smell identification. Patterns of performance highlight learning and memory characteristics unique to OEM (e.g., learning curves, cued and free recall). CONCLUSION: Clinical and research implications include streamlining future versions of the WAOMT to ease patient and administrative burden, and the potential to reliably detect early neuropathological changes in healthy older adults with nonimpaired OEM abilities.

Controlled Rotation of Human Observers in a Virtual Reality Environment.

The low cost and availability of Virtual Reality (VR) systems have supported a recent acceleration of research into perception and behavior under more naturalistic, multisensory, and immersive conditions. One area of research that has particularly benefited from the use of VR systems is multisensory integration, for example, the integration of visual and vestibular cues to give rise to a sense of self-motion. For this reason, an accessible method for the controlled physical rotation of an observer in a virtual environment represents a useful innovation. This paper presents a method for automating the rotation of an office swivel chair along with a method for integrating that motion into a VR experience. Using an example experiment, it is demonstrated that the physical motion, thus produced, is integrated with the visual experience of an observer in a way consistent with expectations; high integration when the motion is congruent with the visual stimulus and low integration when the motion is incongruent.

3D animal camouflage.

Camouflage is a fundamental way for animals to avoid detection and recognition. While depth information is critical for object detection and recognition, little is known about how camouflage patterns might interfere with the mechanisms of depth perception. We reveal how many common camouflage strategies could exploit 3D visual processing mechanisms.

Visual contrast perception in visual snow syndrome reveals abnormal neural gain but not neural noise.

Visual snow syndrome is a neurological condition characterized by a persistent visual disturbance, visual snow, in conjunction with additional visual symptoms. Cortical hyperexcitability is a potential pathophysiological mechanism, which could be explained by increased gain in neural responses to visual input. Alternatively, neural noise in the visual pathway could be abnormally elevated. We assessed these two potential competing neural mechanisms in our studies of visual contrast perception. Cortical hyperexcitation also occurs in migraine, which commonly co-occurs with visual snow syndrome. Therefore, to determine whether the effect of visual snow syndrome can be distinguished from interictal migraine, we recruited four participant groups: controls, migraine alone, visual snow syndrome alone and visual snow syndrome with migraine. In the first experiment, we estimated internal noise in 20 controls, 21 migraine participants and 32 visual snow syndrome participants (16 with migraine) using a luminance increment detection task. In the second experiment, we estimated neural contrast gain in 21 controls, 22 migraine participants and 35 visual snow syndrome participants (16 with migraine) using tasks assessing sensitivity to changes in contrast from a reference. Contrast gain and sensitivity were measured for the putative parvocellular and 'on' and 'off' magnocellular pathways, respectively. We found that luminance increment thresholds and internal noise estimates were normal in both visual snow syndrome and migraine. Contrast gain measures for putative parvocellular processing and contrast sensitivity for putative off magnocellular processing were abnormally increased in visual snow syndrome, regardless of migraine status. Therefore, our results indicate that visual snow syndrome is characterized by increased neural contrast gain but not abnormal neural noise within the targeted pathways.

Lateral inhibition between banks of orientation selective channels predicts shape context effects: A tilt-illusion field.

The perceived shapes of almost circular paths are modified by concentrically placed context paths. These induced changes have previously been attributed to curvature masking. This paper shows that, instead, they can be explained by the impacts of local tilt illusions. First, the tilt-illusion was measured over the full range of orientation differences between short test and context lines and it was shown that the resulting function can be predicted by a model based on a vectorial population response of a bank of orientation selective channels, provided lateral inhibition between channels with the same orientation selectivity and adjacent receptive fields was postulated. Subsequently, it was demonstrated that, if the perceived shape of a test path were modified to accommodate the predicted local tilt-illusion, then this could account for previously reported changes in the detectability of a path sinusoidally modulated in radius. Further, we measured points of subjective vertical in test lines and points of subjective circularity in test paths when surrounded by modulated context paths. The tilt required to null the tilt-illusion approximated the maximum orientation difference from circular measured in the modulated paths at their point of subjective circularity, supporting the proposal that the illusory shape change is due to local changes in the position of the path arising from a response to local tilt illusions induced by the orientation context. An important corollary to this result is that such effects will generalize to all paths which are adjacent.

Analysis of shape uses local apparent position rather than physical position.

Objects are often identified by the shapes of their boundaries. Here, by measuring threshold amplitudes for detection of sinusoidal modulation of local position, orientation and centrifugal speed in a closed path of Gabor patches, we show that the positions of such boundaries are misperceived to accommodate local illusions of orientation context and motion induced positional bias. These two types of illusion are shown to occur independently, but the misperception of position is additive. We conclude that, in the analysis of shape, the visual system uses the apparent rather than the veridical boundary conformation.

The temporal integration windows for visual mirror symmetry.

Symmetry perception in dot patterns is tolerant to temporal delays of up to 60 ms within and between element pairs. However, it is not known how factors effecting symmetry discrimination in static patterns might affect temporal integration in dynamic patterns. One such feature is luminance polarity. Using dynamic stimuli with increasing temporal delay (SOA) between the onset of the first and second element in a symmetric pair, we investigated how four different luminance-polarity conditions affected the temporal integration of symmetric patterns. All four luminance polarity conditions showed similar upper temporal limits of approximately 60 ms. However psychophysical performance over all delay durations showed significantly higher symmetry thresholds for unmatched-polarity patterns at short delays, but also significantly less sensitivity to increasing temporal delay relative to matched-polarity patterns. These varying temporal windows are consistent with the involvement of a fast, sensitive first-order mechanism for matched-polarity patterns, and a slower, more robust second-order mechanism for unmatched-polarity patterns. Temporal integration windows for unmatched-polarity patterns were not consistent with performance expected from attentional mechanisms alone, and instead supports the involvement of second-order mechanisms that combines information from ON and OFF channels.

Using perceptual tasks to selectively measure magnocellular and parvocellular performance: Rationale and a user's guide.

The visual system uses parallel pathways to process information. However, an ongoing debate centers on the extent to which the pathways from the retina, via the Lateral Geniculate nucleus to the visual cortex, process distinct aspects of the visual scene and, if they do, can stimuli in the laboratory be used to selectively drive them. These questions are important for a number of reasons, including that some pathologies are thought to be associated with impaired functioning of one of these pathways and certain cognitive functions have been preferentially linked to specific pathways. Here we examine the two main pathways that have been the focus of this debate: the magnocellular and parvocellular pathways. Specifically, we review the results of electrophysiological and lesion studies that have investigated their properties and conclude that while there is substantial overlap in the type of information that they process, it is possible to identify aspects of visual information that are predominantly processed by either the magnocellular or parvocellular pathway. We then discuss the types of visual stimuli that can be used to preferentially drive these pathways.

Motion direction tuning in centre-surround suppression of contrast.

The perceived contrast of a central stimulus is reduced in the presence of a high contrast surround. A number of stimulus features influence the amount of suppression. A two-mechanism model has been proposed for stationary patterns involving a narrowly-tuned process, requiring very similar stimuli in the centre and surround, and a weaker, untuned or very broadly tuned process unselective for stimulus features. This study examines whether a similar model applies to the motion pathway in human participants by varying the orientation and direction of motion of the surround relative to the centre. Four experienced observers completed a two-interval forced-choice contrast matching task. The stimuli were drifting sinusoidal grating patterns with high contrast surrounds (95%) differing in direction of motion and orientation relative to the centre grating. All surround conditions produced suppression but a common orientation and direction of motion produced significantly more suppression than either opposite direction of motion conditions or orthogonal direction conditions. The tuning for motion direction differences was assessed for same and opposite directions of motion. These findings support the extension of the two-mechanism model of contrast suppression to motion direction.

Shape partitioning interacts with global shape integration.

Objects are often identified by the shape of their profiles but complex objects are often comprised of multiple articulated components. It has been proposed that complex objects are decomposed and recognized by their component parts. This study exploits the proposition that the visual system decomposes objects at matched deep concavities on their boundaries. Rapid decreases in thresholds for detection of sinusoidal deformation of a circle's radius with number of cycles of modulation shows that shape information is integrated around radial frequency (RF) patterns. Here we merge RF patterns to form composite patterns with concavities and show that integration around the RF patterns is disrupted if the concavities are shallow but preserved if they are deep, consistent with their decomposition at matched deep concavities. Geon theory identifies complex patterns through a structural description of viewpoint invariant primitives known as geons. Geons are defined by properties on their boundaries that co-occur in a non-accidental manner across viewpoint changes rather than by reconciling metric properties such as curvature with viewpoint specific templates. Similarly, shapes of RF patterns are defined by the positions of curvature features on their boundaries. We argue that RF patterns provide flexible stimuli that might be used to study geons.

A new visual illusion of aspect-ratio context.

Perception of local properties of the visual field is influenced by aftereffects of adaptation. The tilt aftereffect describes repulsion of the perceived orientation of a line from the orientation of an adapting line. Analogous effects of spatial context are often called illusions. Repulsion of the perceived orientation of a grating from the orientation of a surrounding grating is referred to as the tilt illusion. In the same manner, the size aftereffect and Ebbinghaus illusion form a complementary pair of temporal and spatial context effects of size. Here we report psychophysical evidence for a previously unknown aspect-ratio illusion which causes the perceived aspect-ratio of a rectangle to be repelled from the aspect-ratio of rectangles surrounding it. This illusion provides a spatial analogue to the aspect-ratio aftereffect.

Relating excitatory and inhibitory neurochemicals to visual perception: A magnetic resonance study of occipital cortex between migraine events.

Certain perceptual measures have been proposed as indirect assays of brain neurochemical status in people with migraine. One such measure is binocular rivalry, however, previous studies have not measured rivalry characteristics and brain neurochemistry together in people with migraine. This study compared spectroscopy-measured levels of GABA and Glx (glutamine and glutamate complex) in visual cortex between 16 people with migraine and 16 non-headache controls, and assessed whether the concentration of these neurochemicals explains, at least partially, inter-individual variability in binocular rivalry perceptual measures. Mean Glx level was significantly reduced in migraineurs relative to controls, whereas mean occipital GABA levels were similar between groups. Neither GABA levels, nor Glx levels correlated with rivalry percept duration. Our results thus suggest that the previously suggested relationship between rivalry percept duration and GABAergic inhibitory neurotransmitter concentration in visual cortex is not strong enough to enable rivalry percept duration to be reliably assumed to be a surrogate for GABA concentration, at least in the context of healthy individuals and those that experience migraine.

Phase specific shape aftereffects explained by the tilt aftereffect.

Aftereffects of adaptation are frequently used to infer mechanisms of human visual perception. Commonly, the properties of stimuli are repelled from properties of the adaptor. For example, in the tilt aftereffect a line is repelled in orientation from a previously experienced line. Perceived orientation is predicted by the centroid of the responses of a population of mechanisms individually tuned to limited ranges of orientation but collectively sensitive to the whole possible range. Aftereffects are also predictable if the mechanisms are allowed to adapt. Adaptation across radial frequency patterns, patterns deformed from circular by a sinusoidal modulation of radius, causes repulsive aftereffects, sensitive to the relative amplitudes and orientations of the patterns. Here we show that these shape aftereffects can be accounted for by the application of local tilt aftereffects around the shape contour. We suggest that fields of tilt aftereffects might provide a general mechanism for exaggerating the perceptual difference between successively experienced stimuli, making them more discriminable. If the human visual system does indeed exploit this possibility, then the conclusions often made by studies assuming adaptation within mechanisms sensitive to the shape of stimuli will need to be reconsidered. (PsycINFO Database Record (c) 2019 APA, all rights reserved).