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Int J Pept Protein Res ; 22(2): 251-6, 1983 Aug.
Article in English | MEDLINE | ID: mdl-6618767

ABSTRACT

Synthesis of a series of 3-hydroxynaphthalene-2-carbonylamino acid methyl esters (II-XI) and some of their corresponding hydrazides (XII-XXI), dipeptide methyl esters (XXII-XXXV) and dipeptide hydrazides (XXXVI-XXXIX) is described. 3-Hydroxynaphthalene-2-CO-L-Tyr-N2H3 (XX) and the corresponding L-Val-L-Ala-N2H3 (XXXVI) were found to be active against a number of micro-organisms.


Subject(s)
Amino Acids/chemical synthesis , Anti-Infective Agents/chemical synthesis , Dipeptides/chemical synthesis , Naphthols/chemical synthesis , Amino Acids/pharmacology , Anti-Bacterial Agents , Bacteria/drug effects , Chemical Phenomena , Chemistry , Dipeptides/pharmacology , Fungi/drug effects , Naphthols/pharmacology
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