ABSTRACT
INTRODUCTION: The prevalence of type 1 diabetes is increasing worldwide. The advent of new monitoring devices has enabled tighter glycemic control. AIM: To study the impact of glucose monitoring devices on the everyday life of young children with type 1 diabetes (T1D) and their parents. METHODS: A questionnaire was addressed to parents of children with T1D under the age of 6 years with an insulin pump treated in one of the hospitals of the ADIM network in France between January and July 2020. RESULTS: Among the 114 families included in the study, 53% of parents (26/49) woke up every night to monitor blood glucose levels when their child had flash glucose monitoring (FGM), compared with 23% (13/56) of those whose child had continuous glucose monitoring (CGM). Overall, 81% of parents (86/108) found that glucose monitoring improved their own sleep and parents whose child had CGM were significantly more likely to report improved sleep (86% vs 73%, p = 0.006). Forty-nine percent of parents (55/113) declared that they (in 87% of cases, the mother only) had reduced their working hours or stopped working following their child's T1D diagnosis. Maternal unemployment was significantly associated with the presence of siblings (p = 0.001) but not with glycemic control (p = 0,87). Ninety-eight percent of parents (105/107) think that glucose monitoring improves school integration. CONCLUSION: In these families of children with T1D, new diabetes technologies reduced the burden of care but sleep disruption remained common. Social needs evaluation, particularly of mothers, is important at initial diagnosis of T1D in children.
Subject(s)
Diabetes Mellitus, Type 1 , Child , Humans , Child, Preschool , Diabetes Mellitus, Type 1/diagnosis , Diabetes Mellitus, Type 1/drug therapy , Blood Glucose , Hypoglycemic Agents/therapeutic use , Blood Glucose Self-Monitoring , Continuous Glucose Monitoring , ParentsABSTRACT
We present the ninth case of epidermolysis bullosa acquisita (EBA) reported in children. As in most of the other childhood cases, the 7-year-old boy described herein had an acute, widespread, inflammatory vesiculobullous eruption with oral involvement. Indirect immunofluorescence on salt-split skin as well as Western immunoblot confirmed the diagnosis of EBA. The patient responded to combined prednisone and dapsone, and was maintained with dapsone alone.
Subject(s)
Epidermolysis Bullosa Acquisita/diagnosis , Administration, Oral , Adrenal Cortex Hormones/administration & dosage , Adrenal Cortex Hormones/therapeutic use , Antibodies, Antinuclear , Antimalarials/therapeutic use , Blotting, Western , Child , Child, Preschool , Dapsone/therapeutic use , Drug Therapy, Combination , Epidermolysis Bullosa Acquisita/drug therapy , Female , Humans , Immunoglobulin A/isolation & purification , Immunoglobulin M/isolation & purification , Infant , Male , Skin/chemistrySubject(s)
Acquired Immunodeficiency Syndrome/transmission , Cytomegalovirus Infections/transmission , Opportunistic Infections/transmission , Acquired Immunodeficiency Syndrome/complications , Adult , Cytomegalovirus Infections/complications , Female , Humans , Infant, Newborn , Maternal-Fetal Exchange , Opportunistic Infections/complications , PregnancySubject(s)
Acquired Immunodeficiency Syndrome/transmission , HIV-1 , Toxoplasmosis, Congenital/transmission , Adult , Female , Humans , Infant, Newborn , MaleABSTRACT
Since January 1986, the authors have examined twenty infant HIV positives. In two cases specially, some serious and precocious ophthalmic lesions have been found : an ophthalmic zona appeared at the age of three months, a cytomegalovirus retinitis diagnosed at the age of six months. From this series, the particularities of the HIV infection by maternal-fetal transmission are discussed.
