ABSTRACT
It is studied the skin and annexes innervation of cat and Wistar rat lips with argentic impregnation and acetylcholinesterase technique. It is made evident the existence of a subepithelial plexus from where some nervous fibers leave ending in the epithelial deep stratums and nervous fibers that finish in dermis thickness forming complex ramifications and different type I and II of SETO morphotypes of nervous receptors. They aren't found typical Merckel, Meissner o Paccini mechano-receivers. The nervous terminations in the transition skin-mucous zone are like the ones found in the rest of skin epidermis. Some intraepithelial fibers have been described at level of sudoriferous and sebaceus glands and sensitive corpuscles in connexion with pilous follicles.