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1.
Sci Rep ; 14(1): 3104, 2024 02 07.
Article in English | MEDLINE | ID: mdl-38326414

ABSTRACT

Facial deformities can be caused by cancer, tumours, trauma, infections, congenital or acquired defects and may lead to alteration in basic functions such as communication, breathing, and mastication and aesthetic thereby affecting quality of life. Traditional processes for manufacturing maxillofacial prostheses involve complicated, time-consuming and tedious processes for the patient and the operator. Impression of the defect area, which is the one of the crucial step in fabrication of prosthesis, is the longest and most difficult process as it requires a long contact with the patient. The digital revolution is now changing the landscape of prosthetic production and making the impression making procedure simpler. Digital technology reduces patient chair side time by providing more accurate display data in less time (3-5 min) than traditional methods. Digital impressions eliminate the need for bulky impression materials and provide a more comfortable patient experience.


Subject(s)
Artificial Limbs , Quality of Life , Humans , Tomography, X-Ray Computed , Prosthesis Implantation , Photogrammetry/methods , Computer-Aided Design
2.
J Biomater Appl ; 38(9): 975-988, 2024 04.
Article in English | MEDLINE | ID: mdl-38423069

ABSTRACT

Cranioplasty involves the surgical reconstruction of cranial defects arising as a result of various factors, including decompressive craniectomy, cranial malformations, and brain injury due to road traffic accidents. Most of the modern decompressive craniectomies (DC) warrant a future cranioplasty surgery within 6-36 months. The conventional process of capturing the defect impression and polymethyl methacrylate (PMMA) flap fabrication results in a misfit or misalignment at the site of implantation. Equally, the intra-operative graft preparation is arduous and can result in a longer surgical time, which may compromise the functional and aesthetic outcomes. As part of a multicentric pilot clinical study, we recently conducted a cohort study on ten human subjects during 2019-2022, following the human ethics committee approvals from the participating institutes. In the current study, an important aspect of measuring the extent of bone remodelling during the time gap between decompressive craniectomy and cranioplasty was successfully evaluated. The sterilised PMMA bone flaps were implanted at the defect area during the cranioplasty surgery using titanium mini plates and screws. The mean surgery time was 90 ± 20 min, comparable to the other clinical studies on cranioplasty. No signs of intra-operative and post-operative complications, such as cerebrospinal fluid leakage, hematoma, or local and systemic infection, were clinically recorded. Importantly, aesthetic outcomes were excellent for all the patients, except in a few clinical cases, wherein the PMMA bone flap was to be carefully customized due to the remodelling of the native skull bone. The extent of physiological remodelling was evaluated by superimposing the pre-operative and post-operative CT scan data after converting the defect morphology into a 3D model. This study further establishes the safety and efficacy of a technologically better approach to fabricate patient-specific acrylic bone flaps with improved surgical outcomes. More importantly, the study outcome further demonstrates the strategy to address bone remodelling during the patient-specific implant design.


Subject(s)
Decompressive Craniectomy , Polymethyl Methacrylate , Humans , Decompressive Craniectomy/adverse effects , Decompressive Craniectomy/methods , Retrospective Studies , Skull/surgery , Skull/injuries , Bone Remodeling , Treatment Outcome
3.
Cureus ; 14(10): e30789, 2022 Oct.
Article in English | MEDLINE | ID: mdl-36457623

ABSTRACT

Dental material has emerged in the last few decades with enhanced biological properties. The prime characteristics required for dental materials are that they should be compatible with oral cavity fluids such as saliva and gingival crevicular fluids. Their functionality should be enhanced in the presence of such biological factors. Scientific advancements in exploring innovative materials have led to the possibility of achieving beneficial results by using materials that respond more dynamically to the environment in which they are placed. Currently available dental materials are improvised. Restorative materials such as smart composites, smart ceramics, compomers, resin-modified glass ionomer, amorphous calcium phosphate (ACP)-releasing pit and fissure sealants, and other smart burs and orthodontic shape memory alloys have all benefited from the usage of smart materials in dentistry.

4.
Trials ; 23(1): 1048, 2022 Dec 27.
Article in English | MEDLINE | ID: mdl-36575547

ABSTRACT

BACKGROUND: Facial mutilation and deformities can be caused by cancer, tumours, injuries, infections, and inherited or acquired deformities and has the potential to degrade one's quality of life by interfering with fundamental tasks like communication, breathing, feeding, and aesthetics. Depending on the type of defect, producing maxillofacial prostheses for the rehabilitation of patients with various defects can be challenging and complex. The prosthesis is used to replace missing or damaged parts of the cranium and face, like the nose, auricle, orbit, and surrounding tissues, as well as missing areas of soft and hard tissue, with the primary goal of increasing the patient's quality of life by rehabilitating oral functions such as speech, swallowing, and mastication. Traditional maxillofacial prosthesis impression and fabrication processes include a number of complicated steps that are costly, time-consuming, and uncomfortable for the patient. These rely on the knowledge of the maxillofacial team, dental clinicians, and maxillofacial technician. The foundation of the impression is the keystone for creating a prosthesis. However, this is the most time-consuming and difficult chair-side operation in maxillofacial prosthesis manufacturing since it requires prolonged interaction with the patient. The field of prosthesis fabrication is being transformed by the digital revolution. Digital technology allows for more accurate impression data to be gathered in less time (3 to 5 min) than traditional methods, lowering patient anxiety. Digital impressions eliminate the need for messy impression materials and provide patients with a more pleasant experience. This method bypasses the procedure of traditional gypsum model fabrication. This eliminates the disparity caused by a dimensional distortion of the impression material and gypsum setting expansion. Traditional dental impression processes leave enough room for errors, such as voids or flaws, air bubbles, or deformities, while current technology for prosthesis planning has emerged as an alternative means to improve patient acceptability and pleasure, not only because the end result is a precisely fitted restoration but also because the chair-side adjustments required are reduced. The most frequent approaches for creating 3D virtual models are the following. To begin, 3D scanning is employed, in which the subjects are scanned in three dimensions, and the point cloud data is used to create a virtual digital model. METHODS: It will be a hospital-based randomised control trial, carried out at the Department of Prosthodontics, Sharad Pawar Dental College, Sawangi (Meghe), Wardha, a part of Datta Meghe Institute of Medical Sciences (Deemed University). A total of 45 patients will be selected from the outpatient department (OPD) of the Department of Prosthodontics. All the patients will be provided written consent before their participation in the study. METHODOLOGY: 1. Patient screening will be done, and the patient will be allocated to three techniques that are the conventional manual method, photogrammetry method, and 3D scanning in a randomised manner 2. The impression of the defect will be recorded by conventional manual method, photogrammetry method, and 3D scanning 3. The defect will be modelled in three ways: first is as per the manual dimension taken on the patient, second is the organisation of photographic image taken with lab standards and third is plotting of point cloud data to generate the virtual 3D model 4. For photogrammetric prosthesis design, finite photos/images will be taken at multiple angles to model the 3D virtual design. With the use of minimum photographs, the 3D modelling can be performed by using freeware, and a mould is obtained 5. The CAD software was used to design the prosthesis, and the final negative mould can be printed using additive manufacturing 6. The mould fabricated by all three methods will be analysed by a software using reverse engineering technology Study design: Randomised control trial Duration: 2 years Sample size: 45 patients DISCUSSION: Rodrigo Salazar-Gamarra1, Rosemary Seelaus, and Jorge Vicente Lopes da Silva et al., in the year 2016, discussed, as part of a method for manufacturing face prostheses utilising a mobile device, free software, and a photo capture protocol, that 2D captures of the anatomy of a patient with a facial defect were converted into a 3D model using monoscopic photogrammetry and a mobile device. The visual and technical integrity of the resulting digital models was assessed. The technological approach and models that resulted were thoroughly explained and evaluated for technical and clinical value. Marta Revilla-León, Wael Att, and Dr Med Dent et al. (2020) used a coordinate measuring equipment which was used to assess the accuracy of complete arch implant impression processes utilising conventional, photogrammetry, and intraoral scanning. Corina Marilena Cristache and Ioana Tudor Liliana Moraru et al. in the year 2021 provided an update on defect data acquisition, editing, and design using open-source and commercially available software in digital workflow in maxillofacial prosthodontics. This research looked at randomised clinical trials, case reports, case series, technical comments, letters to the editor, and reviews involving humans that were written in English and included detailed information on data acquisition, data processing software, and maxillofacial prosthetic part design. TRIAL REGISTRATION: CTRI/2022/08/044524. Registered on September 16, 2022.


Subject(s)
Calcium Sulfate , Imaging, Three-Dimensional , Humans , Imaging, Three-Dimensional/methods , Photogrammetry/methods , Prosthesis Design , Quality of Life , Software
5.
Cureus ; 14(5): e25550, 2022 May.
Article in English | MEDLINE | ID: mdl-35783892

ABSTRACT

Understanding the root and canal anatomy is pivotal before initiating endodontic surgical procedures. Any missed canal will cause treatment failure and ultimately lead to tooth extraction in this era of tooth conservation. Mandibular second premolars have attracted researchers and clinicians for having aberrant anatomy. Variations in the number of roots or canals may not be discerned on 2D radiographs and may become apparent during treatment procedures. The occurrence of two roots in the lower second premolar has been reported in the current case. Here, in this case, the authors have described the clinical course of the patient along with the management of these two rooted mandibular second premolars.

6.
Int J Med Robot ; 16(1): e2046, 2020 Feb.
Article in English | MEDLINE | ID: mdl-31675463

ABSTRACT

OBJECTIVES: The objective of this study was to provide the generalized methodology for design and development of a customized implant and customized surgical osteotomy guide (CSOG) for precise mandibular tumor resection and placement of a customized implant in ablative tumor surgery for accurate mandibular reconstruction. METHODS: Medical imaging technique, image processing, virtual surgical planning (VSP), biomedical computer-aided design (CAD), and rapid prototyping (RP) were used to develop CSOG and customized implant. A mock surgical test and an experimental analysis were performed on the biomodel (RP assisted diseased model) to check the effectiveness of the CSOG. RESULTS: The paired t test showed the statistically significant result with the use of CSOG as compared to the without using CSOG in ablative mandibular tumor surgery. CONCLUSIONS: A mock test and an experimental analysis proved that, the precise tumor resection and customized implant placement with minimal gap between bone-implant junctions in mandibular reconstruction using CSOG.


Subject(s)
Dental Implants , Mandibular Neoplasms/surgery , Mandibular Reconstruction/methods , Osteotomy/methods , Surgery, Computer-Assisted/methods , Bone-Implant Interface , Computer-Aided Design , Humans
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