1.
Org Lett
; 16(17): 4536-9, 2014 Sep 05.
Article
in English
| MEDLINE
| ID: mdl-25141097
ABSTRACT
A class of novel thiol-activated H2S donors has been developed on the basis of the gem-dithiol template. These donors release H2S in the presence of cysteine or GSH in aqueous solutions as well as in cellular environments.
Subject(s)
Hydrogen Sulfide/chemistry , Sulfhydryl Compounds/chemistry , Toluene/analogs & derivatives , Cysteine/chemistry , Glutathione/chemistry , Molecular Structure , Toluene/chemistry
2.
Org Lett
; 15(11): 2786-9, 2013 Jun 07.
Article
in English
| MEDLINE
| ID: mdl-23697786
ABSTRACT
"Caged" gem-dithiol derivatives that release H2S upon light stimulation have been developed. This new class of H2S donors was proven, by various spectroscopic methods, to generate H2S in an aqueous/organic medium as well as in cell culture.
