Predictors of Positive Treatment Outcome in People With Anorexia Nervosa Treated in a Specialized Inpatient Unit: The Role of Early Response to Treatment.

OBJECTIVE: To investigate factors which predict positive treatment outcome in inpatients with anorexia nervosa (AN), particularly the role of early treatment response. METHOD: 102 patients entering specialist inpatient treatment were assessed for eating disorder history, psychopathology, and motivation to change. Predictive factors assessed were: early treatment response defined as weight increase of at least 0.5-1 kg/week during the first 6 weeks of treatment (n=87), admission body mass index (BMI), onset age, chronicity, motivation to change, diagnosis, and previous hospitalization for AN. Positive treatment outcome was defined as achieving a BMI of 17.5 kg/m(2) within an individual time frame. RESULTS: Logistic regression indicated that patients were 18 times more likely to reach positive treatment outcome if they met the National Institute for Health and Care Excellence weight guidelines within the first 6 weeks of hospitalization. Higher admission BMI was also found to predict positive treatment outcome. DISCUSSION: Higher entry BMI and early weight gain predict positive treatment outcome in individuals receiving specialist AN inpatient treatment. Copyright © 2016 John Wiley & Sons, Ltd and Eating Disorders Association.

Clinical normative data for eating disorder examination questionnaire and eating disorder inventory for DSM-5 feeding and eating disorder classifications: a retrospective study of patients formerly diagnosed via DSM-IV.

Normative data for measures of eating disorder (ED) psychopathology provide a fundamental description of a presentation and a means to establish clinically significant change following an intervention. Clinical norms for the ED population are lacking and out of date following the publication of Diagnostic and Statistical Manual of Mental Health Disorders (DSM) 5. This study aimed to show that scores from the Eating Disorder Examination Questionnaire (EDE-q) and the Eating Disorder Inventory (EDI) differ across ED diagnosis groups and provide norm data for DSM-5 ED diagnoses. Patients (n = 932) presenting to an out-patient service over 5 years were retrospectively re-diagnosed based on DSM-5 criteria. Statistical analysis showed a significant difference on most subscale scores of the EDE-q and the EDI across diagnosis. Means, standard deviations and percentile ranks are presented by diagnosis. The norms detailed contribute to improving the accuracy with which scores are interpreted when using DSM-5 and aid with the assessment of clinically significant change following treatment.

Factores predictores del tratamiento de la bulimia nerviosa con Terapia Interpersonal / Predictors of Interpersonal Psychotherapy in patients with bulimic eating disorders

Objetivo: Determinar los factores de pronóstico del tratamiento de la bulimia nerviosa con terapia interpersonal. Diseño: 80 pacientes con el diagnostico de Bulimia Nerviosa (BN) o trastornos del comportamiento alimentario no especificados con características de BN (TCANE) fueron tratados con 16 sesiones de terapia interpersonal. Los pacientes fueron evaluados utilizando una entrevista semi-estructural (Clinical Eating Disorders Rating Instrument-CEDRIC). También completaron una batería de cuestionarios para evaluar los niveles de estima personal (Rosenberg Self-esteem Scale -RSE), la psicopatología de los trastornos de la alimentación (Eating Disorders Examination Questionnaire-EDE-Q), la función interpersonal (Inventory of Interpersonal Functioning-IIP-32) y los niveles de depresión (Beck Depression Inventory-BDI). Método: El pronóstico de interés fue definido por la variable de remisión y recuperación. Para el análisis del estudio se realizaron una serie de regresiones logísticas. Resultado: Baja estima personal, y una menor patología en la función interpersonal fueron los factores de peor pronóstico. Conclusión: Aunque la terapia interpersonal es un tratamiento efectivo para las personas que sufren de bulimia nerviosa, los pacientes con estas patologías con baja estima personal y menos problemas interpersonales deberían de ser tratados con otro tipo de terapia.

Objective: To determine predictors of treatment outcomes in patients with Bulimic Eating Disorders treated with Interpersonal Psychotherapy (IPT). Design: Following initial assessment, 80 patients with diagnoses of Bulimia Nervosa or Eating Disorders Not Otherwise Specified (EDNOS), entered treatment in the form of 16 sessions of IPT. Patients were assessed using a validated semi-structure interview (Clinical Eating Disorders Rating Instrument-CEDRIC) and completed measures of self-esteem (Rosenberg Self-esteem Scale-RSE), eating psychopathology (Eating Disorders Examination Questionnaire-EDE-Q), interpersonal functioning (Inventory of Interpersonal Functioning- IIP-32), and depression (Beck Depression Inventory-BDI). Method: Remission and recovery after 16 sessions of IPT were the two outcomes of interest. Univariate analysis and a series of backwards stepping logistic regressions were performed to determine the variables associated with remission and recovery. Result: Low self-esteem and less interpersonal problems were the main predictors of poor outcome. Conclusion: As patients with Bulimic Disorders with low levels of interpersonal problems and high levels of low self-esteem are likely to do less well with IPT, different type of treatment should be offered to them. A randomized controlled trial could explore this hypothesis in more detail.

A case series evaluation of a modified version of interpersonal psychotherapy (IPT) for the treatment of bulimic eating disorders: a pilot study.

OBJECTIVE: To determine the therapeutic outcome of a modified form of (IPT-BNm) amongst patients with Bulimia Nervosa (BN) and Eating Disorders Not Otherwise Specified (EDNOS). METHOD: Following initial assessment, 59 patients with diagnoses of BN or EDNOS entered treatment in the form of 16 sessions of IPT-BNm. At initial assessment, patients completed measures of general psychopathology (SCL-90), Self esteem (RSE), eating psychopathology (EDE-Q), interpersonal functioning (Inventory of Interpersonal Functioning; IIP-32) and depression (BDI). At the middle and end of treatment, EDE-Q, IIP-32 and BDI measures were repeated. RESULTS: By the middle of therapy, patients had made significant improvements in terms of their eating disordered cognitions and behaviours (including reductions in EDE-Q scores, bingeing and self-induced vomiting), interpersonal functioning and levels of depression. CONCLUSIONS: IPT-BNm is an effective treatment for patients with Bulimic Eating Disorders and appears to work quickly, as there were significant reductions in eating disorders symptoms within the first eight sessions of treatment.