Functional Outcomes and Quality of Life After Sacrum Fractures Managed by Either Operative or Conservative Approaches: A Case Series With One-Year Follow-Up.

Background Pelvic fractures caused by high-energy trauma, such as motor vehicle accidents or falls from a considerable height, commonly lead to sacral fractures. Approximately a quarter of sacral fractures are linked to neurological injury, and overlooking these fractures may result in neurological issues such as sexual dysfunction, hindered lower limb functionality, and urinary and rectal difficulties. The main goal of this study is to introduce our patient group who underwent either operative or nonoperative treatment for sacral fractures, with a follow-up period of one year, and assess their functional outcomes. Methodology This is a retrospective review of prospectively collected data from a consecutive series of patients at the Apex Trauma Centre, Sanjay Gandhi Postgraduate Institute of Medical Sciences, Lucknow. A consecutive series of 24 patients (17-55 years old) with sacral fractures treated either operatively or nonoperatively from 2018 to 2023 was studied. A total of 20 patients were available for follow-up questionnaires, and 20 patients participated in a physical examination. Time to final follow-up averaged 27.19 months (range = 12-57 months). The personal data of each patient was collected, including gender, age, comorbidities, concomitant injuries, mechanism of injury, fracture pattern/classification, surgical or nonsurgical treatment, other surgeries, length of surgery, length of hospital stays, adverse events, complications, neurologic and/or motor deficits, bowel and bladder function, and mortality. At a minimum one-year follow-up, the Majeed score, Oswestry Disability Index (ODI) questionnaire, and Gibbon's classification were assessed. Results All fractures were healed. Five patients showed neurological weakness, with three patients having only paresthesia and two patients having lower limb weakness. The mean Majeed score was 75.4, representing a moderate clinical outcome. Final ODI scores averaged 10.6, representing mild disability among patients with sacrum fractures. Overall, 40% of sacrum fractures were associated with sexual dysfunction, with 30% of females and 50% of males reporting this issue. There was no significant difference (p > 0.05) between operated and conservatively managed sacrum fractures concerning ODI scores, neurological deficit, and sexual dysfunction. Conclusions Both male and female patients with traumatic sacrum fractures experienced a significant decrease in their quality of life and sexual function at least 12 months after their surgery. Sacrum fractures are associated with an increased prevalence of sexual dysfunction and bowel/bladder incontinence. Our study findings indicate that patients with sacrum fractures experience similar functional outcomes and incidences of sexual dysfunction irrespective of whether they are managed operatively or conservatively.

Triangular Osteosynthesis as a Surgical Treatment Option for Unstable Sacral Fracture Fixation with Sacroiliac Dislocation: A Case Report.

Introduction: Sacral fractures, which can occur in young individuals following road traffic accidents or falls from a height, as well as in elderly individuals with osteoporosis after minor trauma, are considered a diverse type of fracture. The incidence of non-osteoporotic sacral fractures is estimated to be 2.1/100,000 people, whereas osteoporotic fractures are estimated to affect 1-5% of elderly individuals at risk. Triangular osteosynthesis is a relatively new fixation technique used as a surgical treatment for unstable sacral fractures. It combines transverse fixation with lumbo-pelvis distraction osteosynthesis, providing stability in different planes. The subcategory of triangular osteosynthesis encompasses spinopelvic fixation, which involves the fusion of transverse sacral alar fracture fixation (such as iliosacral screw/s and sacral plate) and unilateral lumbopelvic fixation from the pedicle of L5 to the ipsilateral posterior ilium. The utilization of this technique provides a mechanically advanced approach for stabilizing unstable sacral alar fractures with vertical shear. Once the pelvic ring injury has been reduced, lumbopelvic fixation can assist in preventing the recurrence of vertical displacement in the unstable hemipelvis. Case Report: The patient, a 29-year-old male, experienced a road traffic accident resulting from a collision involving a motorcycle. As a result of the incident, he suffered from an unstable lateral compression type 1 pelvic ring injury, accompanied by an ipsilateral sacroiliac dislocation and a vertical sacral fracture on the opposite side. Computed tomography imaging revealed a right sacroiliac dissociation, a left sacral fracture classified as AO type B1, as well as fractures in both the superior and inferior pubic rami. The pelvic ring of the patient was subjected to closed reduction and percutaneous fixation, accompanied by minimally invasive spinopelvic fixation. The surgical procedure was performed in a single session, involving the reduction and fixation of the right sacroiliac dissociation, followed by lumbopelvic fixation while in the prone position. After a 1-month follow-up, the patient demonstrated the ability to walk without experiencing pain, and the X-ray revealed a stable spinopelvic and sacroiliac fixation. Conclusion: The utilization of triangular osteosynthesis fixation provides a reliable form of fixation that enables the patient to bear complete weight at an early stage of 6 weeks while also preventing any reduction loss in vertical shear transforaminal sacral fractures.

Functional Outcomes of Anterior Cruciate Ligament Reconstruction Using Titanium Adjustable Loop Button and Poly-L-co-DL-Lactic Acid-Beta Tricalcium Phosphate (PLDLA-bTCP) Interference Screws: A Single-Center, Retrospective, Observational Study.

Background The anterior cruciate ligament (ACL) reconstruction is a standard surgery in patients with instability of the knee caused by ACL insufficiency. Several differential procedures using grafts and implants such as loops, buttons, and screws have been described. This study aimed to assess the functional outcomes of ACL reconstruction surgery using titanium adjustable loop buttons and poly-L-co-DL-lactic acid-beta tricalcium phosphate (PLDLA-bTCP) interference screws. Methodology This was a retrospective, observational, single-center, and clinical study. A total of 42 patients who underwent ACL reconstruction at a tertiary trauma center in northern India between 2018 and 2022 were recruited. Data including demographics, details of the injury, surgery, implants, and surgical outcomes were collected from the patients' medical records. Further, post-surgery details such as re-injury, adverse events, International Knee Documentation Committee (IKDC) profiles, and Lysholm knee score were recorded from the enrolled patients through a telephonic follow-up. Pain score and Tegner activity scale were used to compare the knee status before and after surgery. Results At the time of surgery, the mean age of the recruited patients was 31.1 ± 8.8 years, with a male preponderance of 93%. About 57% of patients had left knee injuries. The common symptoms were instability (67%), pain (62%), swelling (14%), and giving away (5%). During surgery, titanium adjustable loop button and PLDLA-bTCP interference screw implants were used in all patients. The mean follow-up time was 21.2 ± 14.2 months. Based on patient responses, the mean IKDC and Lysholm scores were found to be 54.02 ± 5.93 and 94.4 ± 4.73, respectively. Further, the proportion of patients reporting pain decreased from 62% before surgery to 21% after surgery. The mean Tegner score revealed a significant increase in the activity levels of the patients post-surgery compared to pre-surgery (p < 0.05). Lastly, no adverse events or re-injuries were reported in any of the patients during follow-up. Conclusions Our findings revealed a significant improvement in Tegner activity levels and pain scores after surgery. In addition, patient-reported IKDC and Lysholm scores fell under the category of good knee status and function, suggesting a satisfactory functional outcome of ACL reconstruction. Hence, titanium adjustable loop and PLDLA-bTCP interference screws may be a good choice of implants for successful ACL reconstruction surgery.

Outcome of intramedullary nail coated with antibiotic-impregnated cement in chronic osteomyelitis.

Introduction: Chronic osteomyelitis (Chr OM) may result as a sequel of acute hematogenous infection or following open fractures or orthopedic surgeries. Among various osteoarticular infections, Chr OM is one of the most challenging in terms of treatment. In the present study, we evaluate the outcome of antibiotic cement-coated nails in the treatment of chronic pyogenic osteomyelitis and also discuss the future innovations in field of antibiotic-compatible biomaterials for coating the implants. Materials and Methods: Twelve cases of Chr OM (5 hematogenous and 7 exogenous following trauma or surgery) were operated by intramedullary nail coated with antibiotic-impregnated bone cement from September 2018 to January 2021. All the cases had bacteriological confirmation of infection by deep curettage and its subsequent culture sensitivity. K nail was used in 10 cases and elastic stable intramedullary nails were used in 2 cases. Results: Out of 12 cases, 8 were male and 4 were female. The average duration of follow-up was 13 months. Infection was controlled in all the cases (two cases required repeat antibiotic-coated nailing), and there was no incidence of relapse in any case. The control of infection was assessed by clinical assessment and laboratory parameters. Conclusion: Antibiotic cement-coated nails are an effective method in local control of infection in Chr OM without any systemic side effect.

Résumé Introduction: L'ostéomyélite chronique (OM Chr) peut résulter d'une infection hématogène aiguë ou de fractures ouvertes ou chirurgies orthopédiques. Parmi les diverses infections ostéoarticulaires, Chr OM est l'une des plus difficiles en termes de traitement. Dans le présent étude, nous évaluons les résultats des ongles recouverts de ciment antibiotique dans le traitement de l'ostéomyélite pyogénique chronique et discutons également de l'avenir innovations dans le domaine des biomatériaux compatibles avec les antibiotiques pour le revêtement des implants. Matériels et méthodes: Douze cas de Chr OM (5 hématogènes et 7 exogènes à la suite d'un traumatisme ou d'une chirurgie) ont été opérés par clou centromédullaire enduit d'os imprégné d'antibiotique ciment de septembre 2018 à janvier 2021. Tous les cas ont eu une confirmation bactériologique de l'infection par curetage profond et sa sensibilité culturelle. Un clou K a été utilisé dans 10 cas et des clous centromédullaires stables élastiques ont été utilisés dans 2 cas. Résultats: Sur 12 cas, 8 étaient hommes et 4 femmes. La durée moyenne de suivi était de 13 mois. L'infection a été contrôlée dans tous les cas (deux cas ont nécessité une répétition enclouage enduit d'antibiotique), et il n'y a eu aucune incidence de rechute dans tous les cas. Le contrôle de l'infection a été évalué par une évaluation clinique et paramètres de laboratoire. Conclusion: Les ongles enduits de ciment antibiotique sont une méthode efficace dans le contrôle local de l'infection chez les Chr OM sans tout effet secondaire systémique. Mots-clés: Ciment antibiotique, ostéomyélite chronique, clous centromédullaires.

Optimization of Pesticides Spray on Crops in Agriculture using Machine Learning.

Pesticides are chemicals used to eradicate pests. Not only are they used for plant protection and livestock in agriculture, but they are also used in public areas to kill mosquitoes, cockroaches, and other pests. Approximately 95% of the pesticides produced are only used in agriculture for crop protection. Every country wants to increase crop production. To protect their crops from pests, farmers must use pesticides. Exposure to pesticides is increasing day by day, whether occupationally or environmentally. This has resulted in an increase in crop production, but it has numerous adverse effects on human health, animal health, and the environment. Farmers repeatedly use the same pesticides on their crops, which is detrimental to human health and the environment. In this research, according to authors, the repetition of pesticides in agriculture is controlled using adjuvant and machine learning algorithms. An adjuvant is a chemical agent that is inserted within the pesticide product for enhanced pesticide performance. By utilizing an algorithm for machine learning, it is no longer necessary to repeatedly spray the same pesticide over the entire crop field in order to determine which sections of the crop field still require repeated pesticide spraying. In this research, the authors predict that 72.5% of insecticides are used in India. Logical regression classification, polynomial regression, and K-nearest neighbor algorithm (KNN) are applied to detect this required field.

Clinicoradiological Outcome of Concomitant Fractures of Proximal Femur and Femoral Shaft Treated With Second-Generation Cephalomedullary Nailing.

Background The ideal modality of treatment of concomitant fractures of the hip (intertrochanteric/femoral neck) and the femoral shaft is still evolving. The aim of our retrospective study was to assess the clinicoradiological outcome of such fractures managed by closed second-generation cephalomedullary nailing. Methodology The study was conducted among skeletally mature patients presenting within one week of injury who underwent closed second-generation cephalomedullary nailing (proximal femoral nail). Those presenting beyond one week or those who had pathological fractures, incomplete follow-ups, or other modes of fixation were excluded. Functional results were evaluated according to Friedman and Wyman's clinical assessment system. Time required for fracture healing and the presence of any complications were also noted. Results A total of 10 patients with the ipsilateral hip (five intertrochanteric and five femoral neck) and femoral shaft fractures were included in the study. Associated injuries found included fractures of the ipsilateral tibia/fibula at varying levels in three patients; hand and wrist injuries in two patients; and contralateral femoral shaft fracture, ipsilateral patella, bilateral crush injury of the foot, and head and chest injury with brachial plexus injury in one patient each. Four patients were diagnosed with intra-articular knee injuries (ligamentous and meniscal injuries) postoperatively. At the final follow-up, the functional outcome results were good in four, fair in one, and poor in five patients. All femoral neck fractures united at a mean of 15.2 weeks (range: 12.0-18.0 weeks) and intertrochanteric fractures at a mean of 14.0 weeks (range: 12.0-22.0 weeks). However, there was residual varus malunion in two intertrochanteric fractures. Eight femoral shaft fractures were infra-isthmic; of these, four resulted in nonunion (two of hypertrophic and two of atrophic type) and two were found to be in the delayed union, which eventually united by 24 weeks. Conclusions Second-generation cephalomedullary nail is an acceptable, cost-effective, and minimally invasive alternative for the management of concomitant ipsilateral fractures of the hip and supra-isthmic or isthmic femoral shaft fractures. For infra-isthmic fractures, retrograde femoral nail or distal femoral plate along with a separate implant for addressing the hip fracture (either cannulated cancellous screw or dynamic hip screw, preferably in a rendezvous/overlapping manner) are better options.

Is Minimally Invasive Plating Osteosynthesis Better Than Conventional Open Plating for Humeral Shaft Fractures? A Systematic Review and Meta-Analysis of Comparative Studies.

INTRODUCTION: The aim of systematic review and meta-analysis was to find out whether minimally invasive plate osteosynthesis (MIPO) is better than open reduction and internal plate fixation (ORIF) in terms of functional outcome, achieving union (union time and incidence of non-union), intraoperative parameters (surgical duration, blood loss, and radiation exposure), and complications (iatrogenic radial nerve palsy and infection) for humeral shaft fractures. MATERIALS AND METHODS: We searched online databases (Pubmed, Embase, Scopus, and The Cochrane Library) from inception till 3rd September 2020 for articles comparing MIPO with ORIF for humeral shaft fractures. The methodological quality of randomized controlled trials (RCTs) was done by Cochrane Risk of Bias assessment tool 2 (RoB2) and of non-randomized studies (case-control and cohort studies) by Methodological Index for non-randomized studies (MINORS). Meta-analysis was performed using Review Manager 5.4 software. RESULTS: 11 studies (5 RCTs and 6 non-randomized comparative studies) involving a total of 582 patients (MIPO-290, ORIF-292) meeting our inclusion criteria were included in the study. There was no statistically significant difference in pooled analysis of functional outcome scores between MIPO and ORIF. Union time was significantly lesser (mean difference = 3.12 weeks) and incidence of non-union lower (odd's ratio = 0.27) in MIPO group. Surgical duration and intraoperative blood loss were significantly lesser in MIPO group. Iatrogenic radial nerve palsy and infection were higher in ORIF group. CONCLUSIONS: This study showed that MIPO gives similar functional outcomes as compared to ORIF but causes significantly lesser blood loss, requires lesser operative duration and has a lesser incidence of major complications. TRIAL REGISTRATION: International prospective register of systematic reviews (PROSPERO)-CRD42020208346, Date of registration 09/10/2020. SUPPLEMENTARY INFORMATION: The online version contains supplementary material available at 10.1007/s43465-021-00413-6.

How Much has COVID-19 Pandemic Affected Indian Orthopaedic Practice? Results of an Online Survey.

BACKGROUD: Coronavirus Disease 2019 (COVID-19) has spread globally affecting all strata of people including the orthopaedic surgeons of India. We have witnessed a drastic fall in the number of patients. The aim of study was to assess the extent to which the Indian orthopaedic practice has been affected by the pandemic. METHODS: We conducted an online survey amongst currently practicing Indian orthopaedic surgeons. Those currently not in practice or under training or having left clinical practice before the onset of pandemic were excluded. A total of 533 orthopaedic surgeons took part in the study amongst which, complete responses were obtained from 407 individuals. Statistical analysis was done to see the association between demographic profile of study participants and various variables of orthopaedic practice. RESULTS: There was drastic fall in all the parameters of orthopaedic practice. Over half of the practicing surgeons witnessed fall in out-patients over 90%. Most had stopped elective surgeries (64%) and even emergency ones (21%) altogether. More than 50% of doctors had their earnings reduced by > 75%. We found a statistically highly significant association of reduction in earnings with the sector, type of set-up and duration of practice. (p-value < 0.001). CONCLUSION: This study suggests that orthopaedic surgeons across all sectors in different kinds of set-ups have been affected in their out-patient and operative numbers. With regards to earnings, those working in private and running their own (individual) hospitals & clinics have been most severely affected while those in government sector and medical colleges have been affected the least.