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Br J Ophthalmol ; 91(7): 905-7, 2007 Jul.
Article in English | MEDLINE | ID: mdl-17301118

ABSTRACT

AIM: To assess the accuracy of optical coherence tomography (OCT) in detecting damage to a hemifield, patients with hemifield defects confirmed on both static automated perimetry (SAP) and multifocal visual evoked potentials (mfVEP) were studied. METHODS: Eyes of 40 patients with concomitant SAP and mfVEP glaucomatous loss and 25 controls underwent OCT retinal nerve fibre layer (RNFL), mfVEP and 24-2 SAP tests. For the mfVEP and 24-2 SAP, a hemifield was defined as abnormal based upon cluster criteria. On OCT, a hemifield was considered abnormal if one of the five clock hour sectors (3 and 9 o'clock excluded) was at <1% (red) or two were at <5% (yellow). RESULTS: Seventy seven (43%) of the hemifields were abnormal on both mfVEP and SAP tests. The OCT was abnormal for 73 (95%) of these. Only 1 (1%) of the 100 hemifields of the controls was abnormal on OCT. Sensitivity/specificity (one eye per person) was 95/98%. CONCLUSIONS: The OCT RNFL test accurately detects abnormal hemifields confirmed on both subjective and objective functional tests. Identifying abnormal hemifields with a criterion of 1 red (1%) or 2 yellow (5%) clock hours may prove useful in clinical practice.


Subject(s)
Glaucoma/diagnosis , Retinal Ganglion Cells/pathology , Tomography, Optical Coherence , Aged , Evoked Potentials, Visual , Glaucoma/pathology , Glaucoma/physiopathology , Humans , Middle Aged , Nerve Fibers/pathology , Prospective Studies , Sensitivity and Specificity , Visual Field Tests/methods , Visual Fields
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