[Morphological characteristic of tissues, surrounding prosthesis in patients, suffering cutaneo-prosthetic fistulas and paraprosthetic hernias].

While application of the net prostheses in surgery of anterior abdominal wall hernias (AAWH) the complications are noted, such as the prosthesis cyst development, the net wrinkling, migration and separation with the hernia recurrence. Morphological investigation of tissues were conducted in regions of cutaneo-prosthetic fistulas and hernial gates, formatted by the prosthesis edge, in 22 patients, operated for AAWH, in 6 of them cutaneo-prosthetic fistulas were observed. Morphological changes in region of prosthesis, taking part in the hernial defect development, as well as in the wrinkled part of the prosthesis, were characterized by pronounced inflammation, development of rude cicatrices and infiltration of tissues. While durable existence of cutaneo-prosthetic fistulas the prosthesis degradation and destruction occurs as well as the breaks and cracks; on sites of the tissue, surrounding the prosthesis, the microorganisms and fungi vegetations may evolve, trusting its secondary infectioning.

[Scanning electron microscopy of resected ureters in children with ureterohydronephrosis].

Using scanning electron microscopy, various portions of the ureter in reflux and obstructive ureterohydronephrosis in children were evaluated. In the first case, architectonics of the distal portions is preserved, while in the second case connective tissue is proliferated. Differences in the structure of proximal and distal portions in both forms of ureterohydronephrosis consist in inflammatory changes and violation of the integrity of the epithelial lining, edema and infiltration of the underlying layers, especially the inner muscle layer of the distal portion. The wall of the ureter in proximal part is much thinner, especially the muscular and mucous layers.

[Possibility of the liver ultrastructure recovery in intoxication with heavy metals salts].

Experimental studies helped to reveal ultrastructural changes in hepatocytes, caused by prolonged exposure to heavy metals salts taken in combination and ratios characteristic to soil contents near Almalyk mining and smelting enterprise. The authors demonstrated possibility of liver structural recovery via enterosorption with additional antioxidant therapy.

Effect of laser irradiation of donor blood on erythrocyte shape.

Changes in erythrocyte shape in donor blood during storage and after irradiation with He-Ne laser and infrared laser were studied by scanning electron microscopy, thick drop express-method, and morphometry. It was found that laser irradiation delayed the appearance of erythrocytes of pathological shapes (echinocytes, stomatocytes, etc.) in the blood; He-Ne laser produced a more pronounced effect.

[Surgical treatment of septicopyemic form of acute hematogenous osteomyelitis in children].

The results of treatment of 175 children with a septicopyemic form of acute hematogenous osteomyelitis were analyzed. A method of surgical treatment using an original device for osteopuncture and intraosseous infusions was introduced in the clinic with regard to the results of studying morphological features of changes in the contents of the intramedullary canal. This surgical strategy allowed shortening the period of hospital treatment, reduction of the number of complications and avoidance of lethal outcomes of children with the septicopyemic form of the disease.

[Effect of instrumental blood reinfusion on clinical parameters and morphology of erythrocytes during aortocoronary bypass grafting].

Erythrocytic morphological changes were studied in 48 patients with coronary heart disease (CHD) at the stages of coronary artery bypass grafting, in whom intraoperative continuous apparatus (CATS, Fresenius, Germany) reinfusion of lost autoblood was used. The patients with CHD were found to have a significant erythrocytic morphological transformation with the oxygen status compensated by the preserved nonpathological forms of erythrocytes. Intraoperatively stable tissue oxygen delivery and rapid blood loss compensation during coronary artery bypass grafting could be provided by continuous reinfusion of lost autoblood that contained valuable erythrocytes after apparatus elimination of disrupted and degenerative forms.

Scanning electron microscopy of seminiferous tubules and spermatozoa of rats under conditions of thermal exposure.

Convoluted seminiferous tubules and spermatozoa of albino rats under conditions of thermal exposure were studied by scanning electron microscopy. Exposure at 40 degrees C (in a thermostat) for 1 h caused significant changes in spatial structure of the tubules and spermatozoa. The tubular lumens acquired an irregular shape. The integrity of the spermatid layer was disrupted. The spermatozoon heads were deformed, the tails became bifurcated and convoluted. The appearance of erythrocytes on the spermatid surface attested to impairment of the blood-testis barrier.

Healing of bone fractures of rat shin and some immunological indices during magnetic laser therapy and osteosynthesis by the ilizarov method.

The effect of magnetic and laser therapy on healing of bone fractures and blood levels of T and B lymphocytes was studied in rats during osteosynthesis by the Ilizarov method. Laser therapy induced changes in cells attesting to stimulation of reparative processes and normalization of immunological parameters.

[Ultrastructure of the hematoencephalic barrier in subarachnoid hemorrhage and effect of phenobarbital]. / Ul'trastruktura gematoéntsefalicheskogo bar'era pri subarakhnoidal'nom krovoizliianii i deistvii fenobarbitala.

Electron and light microscopies were used to study capillary and astrocytic structural changes by modelling subarachnoid hemorrhage (SAH) and by using oral phenobarbital. The ultrastructural changes determining hydropic disorders and brain edema were found to achieve its maximum on day 3 after SAH. They were manifested by the lamination of the basement membrane, edema of cytoplasm and processes of astrocytes, their cytoplasmic structural depletion. Day 7 was marked by the recovery of impaired structures that became normal by day 14. Phenobarbital could accelerate elimination of hydropic changes. The recovery observed on day 7 was similar to that on day 14 without phenobarbital.

[Prophylaxis of recurrent multiple echinococcosis of the liver in children]. / Profilaktika retsidiva mnozhestvennogo ékhinokokkoza pecheni u detei.

The article presents an experience with treatment of 47 children aged from 3 to 14 with multiple echinococcosis of the liver. The authors have made a comparative analysis of the antiparasitic remedies and of a wide spectrum bactericidal solution of Betadin. The results of microscopic, histological and electron microscopic investigations have shown Betadin to be highly effective and harmless for the intraoperative prophylactics of recurrent echinococcosis. It is expedient to use Betadin for multiple echinococcal lesion of the liver in children.

[The causes of incompetence of the duodenal stump and gastroenteric anastomosis and the means for its prevention in the surgery of duodenal ulcers]. / Prichiny nesostoiatel'nosti kul'ti dvenadtsatiperstnoi kishki i gastroénteroanastomoza i puti ee preduprezhdeniia v khirurgii duodenal'nykh iazv.

Causes of the incompetence of stump sutures in resection of the stomach observed in 90 out of 3479 patients with chronic duodenal ulcers were analyzed. Most patients were found to have a combination of general and local factors. Among the local factors the leading one was appearance of a large inflammatory infiltration around the "active" ulcers. The endoscopic autohemoapplication to the ulcer included in the complex of preoperative preparation of the patients reduced the frequency of incompetence of sutures from 2.58% to 1.33%.

[The morphological changes in the lung after its dissection with a CO2 laser and a plasma scalpel in an experiment]. / Morfologicheskie izmeneniia legkogo posle rassecheniia ego s pomoshch'iu CO2-lazera i plazmennogo skal'pelia v éksperimente.

An advantage of the laser scalpel over the plasma scalpel was shown in experiments in animals (60 observation). On the 3rd-5th days after cutting with a laser the inflammation symptoms subside and on the 7th day there appear fine fibrous connective tissue since the operation with the plasma scalpel is followed by the formation of the fine fibrous connective tissue as late as on the 10th-14th days, the inflammatory reaction being observed up to the 30th day.

[Morphologic features of mucosa and secretory activity of the stomach in patients with duodenal ulcers in obesity]. / Osobennosti morfologii slizisto i obolochki i sekretornaia aktivnost' zheludka u bol'nykh s duodenal'nymi iazvami pri ozhirenii.

Gastric mucosa of obese patients with duodenal ulcer was investigated by means of light and electron microscopy and morphometrically. The comparison of the morphological findings and data on gastric secretion shows that overall volume of functional structures of the parietal and peptic cells providing secretion is smaller in duodenal ulcer patients with obesity than in non-obese patients. Elevated gastric secretion in these patients is maintained by hyperfunction of the corresponding structures.

[Effect of total laser irradiation on migration of mature cells in rat bone marrow]. / Vliianie obshchego oblucheniia lazerom na migratsiiu zrelykh kletok kostnogo mozga krys.

In experiment on 50 white Wistar male rats, total laser radiation was assessed as regards its effect on bone marrow structure and cells migration into the blood and small intestinal mucosa. The unit "ILGI-101" was used on the basis of copper laser for a single radiation procedure. As shown by light and electron microscopy, morphometry, copper laser single total irradiation causes material changes in the bone marrow and peripheral blood of rats. These were most pronounced 1 hour after the irradiation and depended on the cell migration into the small intestinal stroma. 24 hours after the procedure morphological structure of intestinal bone marrow showed a tendency to normalization.