Subject(s)
Air Pollutants, Occupational/poisoning , B-Lymphocytes/drug effects , Chemical Industry , Complement System Proteins/drug effects , Immunosuppressive Agents/poisoning , Lymphopenia/chemically induced , Manganese Compounds , Manganese Poisoning , Occupational Diseases/chemically induced , Sulfates/poisoning , T-Lymphocytes/drug effects , Animals , B-Lymphocytes/immunology , Complement System Proteins/analysis , Disease Models, Animal , Female , Guinea Pigs , Humans , Leukocyte Count/drug effects , Male , Rats , T-Lymphocytes/immunologyABSTRACT
Workers engaged in the production of inorganic manganese salts revealed lesions of the upper respiratory pathways (catarrhal and subatrophic rhinitis, pharyngitis, laryngitis), skin (contact and allergic dermatitis), cardiovascular disorders. They also showed changes of renal function,mineral metabolism,acid stability of erythrocytes. Activation of the B-system of immunity and allergization of the body are also observed.
Subject(s)
Chemical Industry , Health Status , Manganese/adverse effects , Occupational Exposure/adverse effects , Adult , Air Pollutants, Occupational/adverse effects , Dermatitis, Occupational/chemically induced , Dermatitis, Occupational/diagnosis , Dermatitis, Occupational/epidemiology , Female , Humans , Male , Occupational Diseases/chemically induced , Occupational Diseases/diagnosis , Occupational Diseases/epidemiology , Occupational Exposure/statistics & numerical data , Ukraine/epidemiologyABSTRACT
It was established that the major hazardous factor in nitrate, sulphate and manganese basic carbonate processing shops was the dust of the final product. Upper respiratory tract (catarrhal, subatrophic rhinitis, pharyngitis, laryngitis), skin (allergic and contact dermatitis) and cardiac disorders were specified as the predominant pathology among manganese compounds processing shop workers. Mineral exchange disorders, lowered glucose content in the blood and violation in the acid persistence of the erythrocytes were revealed through medical examinations.