1.
Lancet
; 1(8632): 255-9, 1989 Feb 04.
Article
in English
| MEDLINE
| ID: mdl-2563420
ABSTRACT
63 patients with steroid-sensitive, biopsy-proven minimal-change nephrotic syndrome were followed for between 10 and 21 years. 2 died. All the survivors had normal renal function and blood pressure, and only 2 had a single attack. Frequent relapse was more common with young age of onset and in boys. The frequency of relapse fell rapidly over the first 4 years after diagnosis and then plateaued. Relapses continued into adult life. No definite endpoint to the disease could be defined although there was a linear relation between length of remission and risk of subsequent relapse.
Subject(s)
Nephrotic Syndrome/physiopathology , Adolescent , Adult , Age Factors , Child , Child, Preschool , Cyclophosphamide/administration & dosage , Cyclophosphamide/therapeutic use , Drug Administration Schedule , Female , Follow-Up Studies , Humans , Infant , Male , Nephrotic Syndrome/drug therapy , Prednisolone/administration & dosage , Prednisolone/therapeutic use , Prognosis , Recurrence , Remission Induction , Sex Factors
2.
Contrib Nephrol
; 67: 226-8, 1988.
Article
in English
| MEDLINE
| ID: mdl-3208531