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1.
Vasc Endovascular Surg ; 58(2): 230-234, 2024 Feb.
Article in English | MEDLINE | ID: mdl-37646258

ABSTRACT

An otherwise healthy 9-month-old infant was treated for a true aneurysm of the proximal brachial artery. The swelling was first noted at seven months of age. An ultrasound scan showed a 2 cm × 2 cm aneurysm of the left brachial artery at the level of the mid-upper arm. Whole-body magnetic resonance angiography (MRA) confirmed this was a true aneurysm of the brachial artery; there was good distal runoff and no other aneurysms elsewhere. Vasculitis screen was negative. Surgical excision of the aneurysm and reconstruction of the brachial artery was performed with a reversed cephalic vein graft. The patient made an uneventful recovery and was discharged home. We present an overview of the workup report and emphasise that a multi-disciplinary team approach is imperative for assessing and managing this rare condition.


Subject(s)
Aneurysm , Brachial Artery , Infant , Humans , Brachial Artery/diagnostic imaging , Brachial Artery/surgery , Treatment Outcome , Aneurysm/diagnostic imaging , Aneurysm/surgery , Arm , Upper Extremity
2.
J Hand Surg Eur Vol ; 49(4): 483-489, 2024 Apr.
Article in English | MEDLINE | ID: mdl-37747700

ABSTRACT

We evaluated the management of supracondylar paediatric fractures at our institution over a 10-year period in this retrospective cohort study. In total, 762 children with a supracondylar fracture were treated. The mean age of injury was 5.2 years. The incidence of documented nerve and/or vascular injury was 8.3%. A total of 26 patients had early plastic surgeon involvement; of these, 25 had an open exploration. Eight patients required vein grafting for brachial artery reconstruction for intimal tears. There was one nerve rupture requiring repair and 12 children underwent neurolysis. There were 17 late referrals to the plastic surgery service, of which three were explored (two neurolysis, one neuroma resection and sural nerve grafting). In all cases of nerve injury, the deficit took 7.9 months to recover, indicating a more significant injury than neurapraxia. Early exploration of supracondylar fractures allows direct visualization of the extent of neurovascular injury and immediate intervention.Level of evidence: IV.


Subject(s)
Humeral Fractures , Peripheral Nerve Injuries , Vascular System Injuries , Humans , Child , Child, Preschool , Humeral Fractures/surgery , Retrospective Studies , Vascular Surgical Procedures/adverse effects
3.
J Hand Surg Eur Vol ; : 17531934231196421, 2023 Sep 11.
Article in English | MEDLINE | ID: mdl-37694876

ABSTRACT

The present study analyses the relationships between deprivation and obstetric brachial plexus palsy (OBPP). A retrospective observational study was conducted of infants with OBPP seen between 2008 and 2020 (n = 321). The index of multiple deprivation (IMD) was used to assign an IMD rank to patients based on birth postcode and the relationship with OBPP was analysed, including deprivation, gestational diabetes, age at referral and at first assessment. Quintile-based analysis demonstrated over-representation of patients from more deprived neighbourhoods (n = 109, 39%) living in the top 20% most deprived neighbourhoods. A total of 48 (15%) mothers had diabetes and 98 (31%) infants underwent surgical brachial plexus exploration (a marker of disease severity). Neither diabetes, age at referral nor age at first assessment were associated with IMD score. This suggests that neighbourhood deprivation is associated with OBPP, though the mechanisms are unclear. Further studies in this area may enable targeted health intervention for more deprived maternal and infant groups.Level of evidence: III.

4.
J Hand Surg Am ; 48(3): 236-244, 2023 03.
Article in English | MEDLINE | ID: mdl-36623945

ABSTRACT

PURPOSE: Restoration of elbow flexion is an important goal in the treatment of patients with traumatic brachial plexus injury. Numerous studies have described various nerve transfers for neurotization of the musculocutaneous nerve (or its motor branches); however, there is uncertainty over the effectiveness of each method. The aim of this study was to summarize the published evidence in adults with traumatic brachial plexus injury. METHODS: Medline, Embase, medRxiv, and bioRxiv were systematically searched from inception to April 12, 2021. We included studies that reported the outcomes of nerve transfers for the restoration of elbow flexion in adults. The primary outcome was elbow flexion of grade 4 (M4) or higher on the British Medical Research Council scale. Data were pooled using random-effects meta-analyses, and heterogeneity was explored using metaregression. Confidence intervals (CIs) were generated to the 95% level. RESULTS: We included 64 articles, which described 13 different nerve transfers. There were 1,335 adults, of whom 813 (61%) had partial and 522 (39%) had pan-plexus injuries. Overall, 75% of the patients with partial brachial plexus injuries achieved ≥M4 (CI, 69%-80%), and the choice of donor nerve was associated with clinically meaningful differences in the outcome. Of the patients with pan-plexus injuries, 45% achieved ≥M4 (CI, 31%-60%), and overall, each month delay from the time of injury to reconstruction reduced the probability of achieving ≥M4 by 7% (CI, 1%-12%). CONCLUSIONS: The choice of donor nerve affects the chance of attaining a British Medical Research Council score of ≥4 in upper-trunk reconstruction. For patients with pan-plexus injuries, delay in neurotization may be detrimental to motor outcomes. TYPE OF STUDY/LEVEL OF EVIDENCE: Therapeutic IV.


Subject(s)
Brachial Plexus Neuropathies , Brachial Plexus , Elbow Joint , Nerve Transfer , Humans , Adult , Nerve Transfer/methods , Elbow , Brachial Plexus/injuries , Elbow Joint/surgery , Musculocutaneous Nerve/surgery , Brachial Plexus Neuropathies/surgery , Range of Motion, Articular/physiology , Treatment Outcome , Recovery of Function/physiology
5.
J Hand Surg Eur Vol ; 46(7): 725-730, 2021 09.
Article in English | MEDLINE | ID: mdl-33611983

ABSTRACT

The incidence of brachial plexus injuries in anterior shoulder dislocation remains relatively uncommon. A retrospective study was conducted to observe the natural neurological recovery of patients following these injuries over a 2-year period. Muscle power according to the Medical Research Council scale and sensation were measured from presentation to discharge. In 28 patients, the power grade of proximal muscles supplied by nine injured nerves failed to improve over a median follow-up of 5 months. There was no statistically significant improvement in sensation over a median follow-up of 6 months. Poorer recovery in muscle power score was related to advancing age, whereby every decade increased the risk by approximately 30%. Anterior shoulder dislocation with a plexus injury carries a risk of permanent nerve injury. Patients should be referred for specialist nerve assessment leading to rehabilitation and timely early nerve reconstruction, if indicated.Level of evidence: IV.


Subject(s)
Brachial Plexus Neuropathies , Brachial Plexus , Nerve Transfer , Shoulder Dislocation , Brachial Plexus Neuropathies/etiology , Brachial Plexus Neuropathies/surgery , Humans , Neurosurgical Procedures , Retrospective Studies , Shoulder Dislocation/etiology , Shoulder Dislocation/surgery , Treatment Outcome
6.
J Craniofac Surg ; 32(1): e43-e45, 2021.
Article in English | MEDLINE | ID: mdl-32833811

ABSTRACT

BACKGROUND: Herein, the author report a severe case of large facial mixed germ line tumor associated with neuronal migration disorder, polymicrogyria, and corpus callosum agenesis. This specific association has not been reported as yet. METHOD: A 33-year-old primiparous woman at 38th week, delivered 3820 g male baby, via Cesarian section. Postpartum profuse bleeding was noticed from a large, ulcerative, 7 cm exophytic left facial mass, which was controlled nonoperatively. The treatment included surgical excision and 560 g of large facial tumor. Histology results revealed mixed germ line tumor with grade 3, immature teratoma. RESULTS: Four months postoperatively the teratoma recurred in the buccal, tonsillar, and parapharyngeal areas. Fourteen months following the initial surgical excision the patient died from airway obstruction. CONCLUSION: Due to poor initial prognosis further treatment of the facial malignancy was not feasible. However, initial, early postnatal, excisional surgery provided a prolonged and better quality of life for the patient and family.


Subject(s)
Agenesis of Corpus Callosum , Polymicrogyria , Teratoma , Adult , Agenesis of Corpus Callosum/etiology , Corpus Callosum , Female , Humans , Male , Neoplasm Recurrence, Local , Polymicrogyria/etiology , Pregnancy , Quality of Life , Teratoma/complications , Teratoma/surgery
8.
J Hand Surg Am ; 43(4): 386.e1-386.e7, 2018 04.
Article in English | MEDLINE | ID: mdl-29169721

ABSTRACT

PURPOSE: In our experience, and from the personal report of others, children with obstetrical brachial plexus palsy appear to lose some of their initially recovered active range of motion over the time in both operated and nonsurgical patients. This study investigates whether such a diminution of active movement occurs over time. METHODS: We performed a retrospective analysis of data from our obstetrical brachial plexus clinic. Between 1991 and 2000, 139 patients with a minimum follow-up of 10 years were included in the study. Patients were divided into a nonsurgical group (n = 42) and a group who underwent either primary or secondary brachial plexus reconstruction or both (n = 97). Fifteen joint movements were assessed at 2, 4 to 6, and 9 to 11 years of age and at later final follow-up using the Active Movement Scale. Repeated measures analysis using age at each visit as the repeated measures covariate was undertaken. RESULTS: Active movement scores were not diminished when patients were evaluated at the 10-year follow-up visit. CONCLUSIONS: The suggested loss of active range of motion over time is not demonstrated at 10-year follow-up. TYPE OF STUDY/LEVEL OF EVIDENCE: Prognostic III.


Subject(s)
Brachial Plexus Neuropathies/physiopathology , Brachial Plexus/injuries , Joints/physiopathology , Range of Motion, Articular/physiology , Upper Extremity/physiopathology , Birth Injuries/physiopathology , Brachial Plexus/physiopathology , Brachial Plexus Neuropathies/therapy , Child , Child, Preschool , Follow-Up Studies , Humans , Joints/surgery , Orthopedic Procedures , Retrospective Studies , Upper Extremity/surgery
9.
Surgeon ; 14(3): 129-35, 2016 Jun.
Article in English | MEDLINE | ID: mdl-25261278

ABSTRACT

UNLABELLED: Soft tissue sarcomas are a rare group of mesenchymal tumours the treatment of which poses oncological and reconstructive challenges. Limb-salvage surgery aims to balance adequate excision margins for disease control and preservation of important structures to retain function. Reported here is the review of the Hull Plastic surgery sarcoma service over a twelve year period. METHOD: We performed a review of the Hull sarcoma database over a twelve year period between 1997 and 2009. Demographic data, tumour grade, operative details complications and outcomes were recorded. RESULTS: The database contained a total of 435 patients with a diagnosis of sarcoma. 110 were treated at the Plastic Surgery department over a period of 12 years between 1997 and 2009. The patients treated in our department consisted of 67 males and 43 females (median age 70 years). The most common histological type was leiomyosarcoma (n = 23). Distribution of anatomical sites affected were head and neck (n = 15), upper limb (n = 17), lower limb (n = 56), trunk (n = 22). Large tumours (greater than 8 cm) n = 30, deep tumours n = 48, and high grade (Trojani 3) n = 33. Patients were treated with surgical excision and postoperative radiotherapy in the high grade groups (2 and 3). A range of reconstructive procedures were required from skin grafting, functional muscle transfer and free flap reconstruction. Nine patients developed regional recurrence, six patients had grade 3 tumours. Three were not resectable. Fourteen patients developed distant metastases, seven had grade 3 tumours, six underwent chemotherapy, two were treated palliatively. There were twenty deaths in this group, of which sixteen were sarcoma related. Deaths in the high risk groups was seven (high grade), nine (deep tumours) and eight (tumour size >8 cm). There were six survivors from eleven in the group with all three of these risk factors. CONCLUSION: This study summarises the management of sarcoma form one unit over a twelve year period and lends further evidence to the fact that the principles of limb-salvage surgery are applicable to a wide range of tumour-types and grades, to all patient age groups and anatomical sites with good functional results and that local and free flap reconstruction provides wound cover robust enough to withstand courses of radiotherapy. Early recurrence of high-grade disease and the development of metastasis carry a worse prognosis, especially if adjuvant therapy cannot be given. LEVEL OF EVIDENCE: 4.


Subject(s)
Sarcoma/pathology , Sarcoma/surgery , Adult , Aged , Aged, 80 and over , Combined Modality Therapy , Female , Humans , Limb Salvage , Male , Middle Aged , Plastic Surgery Procedures , Retrospective Studies , Sarcoma/mortality , Treatment Outcome , Young Adult
10.
Plast Reconstr Surg ; 135(2): 397e-400e, 2015 Feb.
Article in English | MEDLINE | ID: mdl-25626824

ABSTRACT

Corneal anesthesia is a debilitating condition which can ultimately lead to blindness from repetitive corneal injury and scarring. We have developed a minimally invasive technique for corneal re-innervation that we have used with excellent results in ten eyes. This article and accompanying video describes the relevant anatomy and demonstrates the technique in detail.


Subject(s)
Cornea/innervation , Corneal Diseases/surgery , Hypesthesia/surgery , Nerve Transfer/methods , Ophthalmic Nerve/surgery , Sural Nerve/transplantation , Adult , Child , Corneal Diseases/congenital , Corneal Diseases/etiology , Corneal Diseases/physiopathology , Corneal Injuries/complications , Eye Pain/etiology , Humans , Hypesthesia/congenital , Hypesthesia/etiology , Hypesthesia/physiopathology , Minimally Invasive Surgical Procedures , Nerve Regeneration , Ophthalmic Nerve/physiology , Pain, Postoperative/etiology , Transplantation, Heterotopic
11.
Pediatr Neurol ; 51(3): 453-6, 2014 Sep.
Article in English | MEDLINE | ID: mdl-25160554

ABSTRACT

BACKGROUND: Thoracic outlet syndrome is rare in children but may have serious consequences. Compression of the neurovascular structures at the thoracic outlet by anomalous soft tissues or cervical ribs may cause neurological deficits in the upper limb and venous or arterial insufficiency. PATIENTS: The symptoms and signs of this condition are well documented, but we describe two patients with an atypical presentation. We review similar published cases where delay in diagnosis resulted in cerebrovascular catastrophe. Our patients presented with relatively nonspecific central nervous system symptoms and were found to have thoracic outlet compression. Both were treated by surgical decompression of the thoracic outlet, and the symptoms completely resolved with no long-lasting neurological consequences. CONCLUSIONS: We highlight the importance of these rare cases because of the risk of stroke and discuss the theory behind the pathological process.


Subject(s)
Thoracic Outlet Syndrome/pathology , Thromboembolism/pathology , Adolescent , Cerebral Angiography , Child , Diagnosis, Differential , Female , Humans , Male , Thoracic Outlet Syndrome/diagnosis , Thoracic Outlet Syndrome/surgery , Thromboembolism/diagnosis , Thromboembolism/surgery
12.
JAMA Ophthalmol ; 132(11): 1289-95, 2014 Nov.
Article in English | MEDLINE | ID: mdl-25010775

ABSTRACT

IMPORTANCE: Corneal anesthesia is recalcitrant to conventional treatment and can lead to permanent visual loss. OBJECTIVE: To assess the outcomes of a novel sensory reconstructive technique for the treatment of corneal anesthesia. DESIGN, SETTING, AND PARTICIPANTS: This prospective study evaluating a new technique was conducted at a tertiary referral center. Four eyes in 3 patients with corneal anesthesia underwent nerve transfers with nerve grafting to restore corneal sensation. Corneal sensory reconstruction was performed using a segment of the medial cutaneous branch of the sural nerve. Two patients with unilateral trigeminal nerve anesthesia-one following basal skull fracture and another following large posterior fossa tumor resection-underwent corneal sensory reconstruction using the contralateral supratrochlear nerve as the donor sensory nerve. One patient with a history of cerebellar hypoplasia and bilateral congenital corneal anesthesia underwent bilateral corneal sensory reconstruction using the respective ipsilateral supratrochlear nerves as the sensory donor nerves. Corneal anesthesia was evaluated preoperatively and postoperatively in the center of the cornea and in 4 corneal quadrants using a Cochet-Bonnet esthesiometer (Luneau). Complications of the procedure were also documented. MAIN OUTCOMES AND MEASURES: Esthesiometry scores. RESULTS: All eyes had prior complications of corneal anesthesia and had no measurable corneal sensation in the affected eye(s) preoperatively. Two patients-one with cerebellar hypoplasia and the other with posterior fossa tumor resection-had markedly improved corneal sensation 6 months postsurgery (3 eyes; mean [SD] central esthesiometry, 55 [5] mm). A third patient with a history of basal skull fracture underwent unilateral corneal neurotization and recovered 15-mm esthesiometry score centrally after 7.5 months of follow-up. None of the operated on eyes have developed corneal anesthesia-related complications since reconstruction. CONCLUSIONS AND RELEVANCE: Corneal sensory reconstruction provides corneal sensation in previously anesthetic corneas. This can be achieved with minimal morbidity using sural nerve grafts, which surgeons commonly use to reconstruct nerve gaps elsewhere. This multidisciplinary approach restores an ocular defense mechanism and may enable subsequent corneal transplant in these patients.


Subject(s)
Cornea/physiology , Corneal Diseases/surgery , Hypesthesia/surgery , Nerve Transfer , Ophthalmic Nerve/surgery , Sural Nerve/transplantation , Trochlear Nerve/transplantation , Adolescent , Child , Cornea/innervation , Corneal Diseases/physiopathology , Female , Humans , Hypesthesia/physiopathology , Male , Neurosurgical Procedures , Ophthalmologic Surgical Procedures , Prospective Studies
20.
Plast Reconstr Surg ; 117(7): 2212-8, 2006 Jun.
Article in English | MEDLINE | ID: mdl-16772919

ABSTRACT

BACKGROUND: The purpose of this article is to identify factors that make hands look youthful or old and to assess whether altering any of these factors could influence the perceived age of the patient. METHODS: A questionnaire showing digital images of female hands of different ages was administered. Some images were altered digitally to remove veins, blemishes, or wrinkles. Makeup and jewelry were added to others. A total of 93 questionnaires were completed. Statistical analysis of results with chi-square test was performed. RESULTS: Wrinkles, veins, prominent joints, thin skin, deformity, and spots characterized old hands. Fullness, lack of veins, and lack of wrinkles characterized young hands. Images with veins removed looked younger than the originals, and this was statistically significant in all cases. Images with added makeup and jewelry were also felt to look younger, but this was not statistically significant. Alterations to images of very elderly hands did not make them look younger. CONCLUSIONS: The authors have established factors that characterize the age of hands and established that hands with less visible veins, in general, look younger. Previous articles have claimed that fat grafting reduces the visibility of veins.


Subject(s)
Aging , Hand , Visual Perception , Adolescent , Adult , Age Factors , Aged , Aged, 80 and over , Cosmetic Techniques , Female , Hand/blood supply , Hand Joints , Humans , Image Processing, Computer-Assisted , Male , Middle Aged , Photography , Rejuvenation , Skin , Subcutaneous Tissue , Surveys and Questionnaires , Veins
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