ABSTRACT
A group of patients with a patch-test positive to nickel sulphate, was selected within a population suffering from pseudo-allergic chronic cutaneous manifestations. On the ground of the results of dietary restriction and oral challenge, the Authors reach the conclusion that the intolerance to nickel salts is to be considered in these patients the mayor factor in the development of skin disorders.
Subject(s)
Food Hypersensitivity/etiology , Nickel/adverse effects , Skin Diseases/chemically induced , Adolescent , Adult , Female , Food Hypersensitivity/diagnosis , Food Hypersensitivity/diet therapy , Humans , Male , Middle Aged , Skin TestsABSTRACT
The rate of the irritable bowel syndrome (IBS) and the follow-up of its symptoms on diet and in therapy with disodium cromoglycate have been studied in a group of patients suffering from mainly extra-digestive symptoms related to food intolerance. Following our observation, we can draw the conclusion that food additives intolerance may be a major factor in the pathogenesis of IBS.