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Rapid Commun Mass Spectrom ; 15(24): 2383-6, 2001.
Article in English | MEDLINE | ID: mdl-11746906

ABSTRACT

The effect of impurity (sodium sulfate Na2SO4; copper sulfate CuSO4; potassium ferrocyanide K4Fe(CN)6; and triammonium citrate (NH4)3C6H5O7) concentration on the positive matrix-assisted laser desorption/ionization time-of-flight (MALDI-TOF) spectra of insulin is described. 2,5-Dihydroxybenzoic acid was used as a desorption matrix. The estimated maximum concentrations of tested salts for which no insulin signal was observed were determined.


Subject(s)
Gentisates , Hypoglycemic Agents/analysis , Insulin/analysis , Drug Contamination , Hydroxybenzoates , Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization
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