Intravenous sedation in dental surgery.

A study on intravenous sedation in dental surgery was conducted comparing diazepam and fentanyl with midazolam and fentanyl. The total number of patients was one hundred and eighty patients. One hundred and twenty patients received diazepam and fentanyl, and later when midazolam was available sixty patients received this drug with fentanyl. The cardiovascular effects, the anterograde amnesia and adverse venous sequelae were investigated. Both drugs gave safe and acceptable sedation. The diazepam group had more venous sequelae. The midazolam group had better amnesia effects with no incidence of venous sequelae.